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AU2002348151A1 - Viral vector production methods and compositions - Google Patents

Viral vector production methods and compositions

Info

Publication number
AU2002348151A1
AU2002348151A1 AU2002348151A AU2002348151A AU2002348151A1 AU 2002348151 A1 AU2002348151 A1 AU 2002348151A1 AU 2002348151 A AU2002348151 A AU 2002348151A AU 2002348151 A AU2002348151 A AU 2002348151A AU 2002348151 A1 AU2002348151 A1 AU 2002348151A1
Authority
AU
Australia
Prior art keywords
compositions
viral vector
production methods
vector production
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002348151A
Inventor
Chad Atwell
Sami Cardak
Miguel E. Carrion
Megan Fitzpatrick
Brenk K. Harris
Christon Hill
Shoupeng Lai
Lee-Cheng Liu
Alena Lizonova
Stephen Morris
Perry Newton
Lu Qin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genvec Inc
Original Assignee
Genvec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genvec Inc filed Critical Genvec Inc
Publication of AU2002348151A1 publication Critical patent/AU2002348151A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351—Methods of production or purification of viral material

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2002348151A 2001-11-05 2002-10-31 Viral vector production methods and compositions Abandoned AU2002348151A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US33287301P 2001-11-05 2001-11-05
US60/332,873 2001-11-05
US33212001P 2001-11-13 2001-11-13
US60/332,120 2001-11-13
PCT/US2002/035049 WO2003039459A2 (en) 2001-11-05 2002-10-31 Viral vector production methods and compositions

Publications (1)

Publication Number Publication Date
AU2002348151A1 true AU2002348151A1 (en) 2003-05-19

Family

ID=26988068

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002348151A Abandoned AU2002348151A1 (en) 2001-11-05 2002-10-31 Viral vector production methods and compositions

Country Status (2)

Country Link
AU (1) AU2002348151A1 (en)
WO (1) WO2003039459A2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007016250A1 (en) * 2005-07-28 2007-02-08 Genvec, Inc. Method of purifying protein
HUE072183T2 (en) 2009-05-02 2025-10-28 Genzyme Corp Gene therapy for neurodegenerative diseases
JP6009357B2 (en) * 2010-01-12 2016-10-19 バスキュラー バイオジェニックス リミテッド Method for producing adenovirus vector and virus preparation produced thereby
US20140315294A1 (en) * 2011-11-24 2014-10-23 Genethon Scalable lentiviral vector production system compatible with industrial pharmaceutical applications
KR102015933B1 (en) * 2012-04-08 2019-08-29 인벤트프라이즈 엘엘씨 Systems and methods of virus propagation in cell culture for vaccine manufacture
EP3460049A1 (en) 2013-02-22 2019-03-27 Genzyme Corporation Microcarrier perfusion culturing methods and uses thereof
AU2014218723B2 (en) 2013-02-22 2019-12-05 Genzyme Corporation Microcarrier perfusion culturing methods and uses thereof
BR112015022292A2 (en) * 2013-03-15 2017-07-18 Childrens Hospital Philadelphia scalable manufacturing process for producing recombinant lentiviral vectors in a serum free suspension cell culture system
CA2920191C (en) * 2013-07-18 2022-03-01 Children's Hospital Medical Center Methods of improving titer in transfection-based production systems using eukaryotic cells
CN106232800B (en) 2014-03-25 2020-07-03 泰尔茂比司特公司 Passive replacement of media
TWI743024B (en) 2014-06-06 2021-10-21 美商健臻公司 Perfusion culturing methods and uses thereof
TWI776235B (en) 2014-06-09 2022-09-01 美商健臻公司 Seed train processes and uses thereof
US11306341B2 (en) 2014-12-22 2022-04-19 Genzyme Corporation Methods of culturing a mammalian cell
EP3054007A1 (en) 2015-02-09 2016-08-10 Institut National De La Sante Et De La Recherche Medicale (Inserm) Recombinant adeno-associated virus particle purification comprising an immuno-affinity purification step
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
CN109415696A (en) 2016-05-25 2019-03-01 泰尔茂比司特公司 Cell amplification
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11000561B2 (en) * 2016-11-04 2021-05-11 Takeda Pharmaceutical Company Limited Adeno-associated virus purification methods
WO2018184028A2 (en) 2017-03-31 2018-10-04 Terumo Bct, Inc. Cell expansion
KR102643016B1 (en) * 2017-04-10 2024-02-29 에피센트알엑스, 인코포레이티드 Method for producing recombinant virus
US11603527B2 (en) * 2017-12-27 2023-03-14 Global Life Sciences Solutions Usa Llc Method and kit for viral vector isolation
CN110317832B (en) * 2018-03-28 2022-07-05 西比曼生物科技（香港）有限公司 Method for preparing purified preparation of recombinant lentiviral vector on GMP scale
CN110317791A (en) 2018-03-29 2019-10-11 西比曼生物科技（香港）有限公司 The method of GMP grades of serum free suspension cell large-scale production slow virus
CN116590346B (en) * 2020-09-15 2024-05-14 上海药明巨诺生物医药研发有限公司 Lentiviral vector purification method
JP2023547618A (en) 2020-10-23 2023-11-13 オロジー バイオサーヴィシズ、インク． Method for infecting cells with viruses
KR20230170728A (en) * 2021-04-14 2023-12-19 젠자임 코포레이션 Perfusion culture method of mammalian cells

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997008298A1 (en) * 1995-08-30 1997-03-06 Genzyme Corporation Chromatographic purification of adenovirus and aav
EP1707631A3 (en) * 1996-11-20 2006-12-27 Introgen Therapeutics, Inc. An improved method for the production and purification of adenoviral vectors
US6261823B1 (en) * 1996-12-13 2001-07-17 Schering Corporation Methods for purifying viruses
US6303362B1 (en) * 1998-11-19 2001-10-16 The Board Of Trustees Of The Leland Stanford Junior University Adenoviral vector and methods for making and using the same
US6168941B1 (en) * 2000-04-07 2001-01-02 Genvec, Inc. Method of producing adenoviral vector stocks

Also Published As

Publication number Publication date
WO2003039459A3 (en) 2003-11-20
WO2003039459A2 (en) 2003-05-15

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase