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AU2002228912A1 - Short peptides from the "a-region" of protein kinases which selectively modulate protein kinase activity - Google Patents

Short peptides from the "a-region" of protein kinases which selectively modulate protein kinase activity

Info

Publication number
AU2002228912A1
AU2002228912A1 AU2002228912A AU2891202A AU2002228912A1 AU 2002228912 A1 AU2002228912 A1 AU 2002228912A1 AU 2002228912 A AU2002228912 A AU 2002228912A AU 2891202 A AU2891202 A AU 2891202A AU 2002228912 A1 AU2002228912 A1 AU 2002228912A1
Authority
AU
Australia
Prior art keywords
region
kinase activity
short peptides
selectively modulate
protein kinase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002228912A
Other languages
English (en)
Inventor
Shmuel Ben-Sasson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yissum Research Development Co of Hebrew University of Jerusalem
Boston Childrens Hospital
Original Assignee
Yissum Research Development Co of Hebrew University of Jerusalem
Boston Childrens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Research Development Co of Hebrew University of Jerusalem, Boston Childrens Hospital filed Critical Yissum Research Development Co of Hebrew University of Jerusalem
Publication of AU2002228912A1 publication Critical patent/AU2002228912A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2002228912A 2000-12-11 2001-12-11 Short peptides from the "a-region" of protein kinases which selectively modulate protein kinase activity Abandoned AU2002228912A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/734,520 2000-12-11
US09/734,520 US20020115173A1 (en) 2000-12-11 2000-12-11 Short peptides from the 'A-region' of protein kinases which selectively modulate protein kinase activity
PCT/US2001/047443 WO2002048336A2 (fr) 2000-12-11 2001-12-11 Peptides courts provenant de la 'region a' des proteines kinases modulant de maniere selective l'activite des proteines kinases

Publications (1)

Publication Number Publication Date
AU2002228912A1 true AU2002228912A1 (en) 2002-06-24

Family

ID=24952020

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002228912A Abandoned AU2002228912A1 (en) 2000-12-11 2001-12-11 Short peptides from the "a-region" of protein kinases which selectively modulate protein kinase activity

Country Status (3)

Country Link
US (2) US20020115173A1 (fr)
AU (1) AU2002228912A1 (fr)
WO (1) WO2002048336A2 (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI329105B (en) * 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
US20030219846A1 (en) * 2002-02-28 2003-11-27 Pfizer Inc. Assay for activity of the ActRIIB kinase
EP1651671A2 (fr) 2003-07-30 2006-05-03 University Of Pittsburgh Of The Commonwealth System Of Higher Education Agonistes d'epitope de cellule t epha2 t et utilisations correspondantes
ES2421139T3 (es) 2003-07-30 2013-08-29 Rigel Pharmaceuticals, Inc. Compuestos de 2,4-pirimidindiamina para su uso en el tratamiento o la prevención de enfermedades autoinmunitarias
US7485297B2 (en) * 2003-08-12 2009-02-03 Dyax Corp. Method of inhibition of vascular development using an antibody
CA2535171A1 (fr) * 2003-08-12 2005-03-03 Dyax Corp. Ligands se fixant au tie 1
US7871610B2 (en) * 2003-08-12 2011-01-18 Dyax Corp. Antibodies to Tie1 ectodomain
CN1956994B (zh) * 2004-03-31 2012-09-05 特许技术开发株式会社 上皮系细胞增殖促进剂
US8158586B2 (en) 2005-04-11 2012-04-17 Pharmagap Inc. Inhibitors of protein kinases and uses thereof
US7491732B2 (en) 2005-06-08 2009-02-17 Rigel Pharmaceuticals, Inc. Compositions and methods for inhibition of the JAK pathway
US20070203161A1 (en) * 2006-02-24 2007-08-30 Rigel Pharmaceuticals, Inc. Compositions and methods for inhibition of the jak pathway
WO2007098507A2 (fr) 2006-02-24 2007-08-30 Rigel Pharmaceuticals, Inc. Compositions et méthodes destinées à l'inhibition de la voie jak
WO2008089070A2 (fr) * 2007-01-12 2008-07-24 Dyax Corp. Polythérapie pour le traitement du cancer
MX2010008926A (es) 2008-02-15 2011-02-23 Rigel Pharmaceuticals Inc Compuestos de pirimidin-2-amina y su uso como inhibidores de jak cinasas.
NZ589315A (en) 2008-04-16 2012-11-30 Portola Pharm Inc 2,6-diamino-pyrimidin-5-yl-carboxamides as Spleen tryosine kinase (syk) or Janus kinase (JAK) inhibitors
US8138339B2 (en) 2008-04-16 2012-03-20 Portola Pharmaceuticals, Inc. Inhibitors of protein kinases
NZ588830A (en) 2008-04-22 2012-11-30 Portola Pharm Inc Inhibitors of protein kinases
US9102625B2 (en) 2010-11-01 2015-08-11 Portola Pharmaceuticals, Inc. Nicotinamides as JAK kinase modulators
US9067988B2 (en) 2010-12-01 2015-06-30 Alderbio Holdings Llc Methods of preventing or treating pain using anti-NGF antibodies
US9539324B2 (en) 2010-12-01 2017-01-10 Alderbio Holdings, Llc Methods of preventing inflammation and treating pain using anti-NGF compositions
NZ611076A (en) 2010-12-01 2015-09-25 Alderbio Holdings Llc Anti-ngf compositions and use thereof
US9884909B2 (en) 2010-12-01 2018-02-06 Alderbio Holdings Llc Anti-NGF compositions and use thereof
US9078878B2 (en) 2010-12-01 2015-07-14 Alderbio Holdings Llc Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75
US11214610B2 (en) 2010-12-01 2022-01-04 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
WO2012087943A2 (fr) * 2010-12-20 2012-06-28 The Regents Of The University Of Michigan Inhibiteurs de l'interaction de liaison entre le récepteur du facteur de croissance épidermique et la protéine de choc thermique 90
EP2782579B1 (fr) 2011-11-23 2019-01-02 Portola Pharmaceuticals, Inc. Inhibiteurs de de la pyrazine kinase
US9676756B2 (en) 2012-10-08 2017-06-13 Portola Pharmaceuticals, Inc. Substituted pyrimidinyl kinase inhibitors
CN115443150A (zh) 2019-12-17 2022-12-06 德克萨斯大学系统董事会 新型ddr1抗体和其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6174993B1 (en) * 1997-05-21 2001-01-16 The Children's Medical Center Corp. Short peptides which selectively modulate the activity of serine/threonine kinases
US6723694B1 (en) * 1997-05-21 2004-04-20 The Children's Medical Center Corp. Short peptides which selectively modulate intracellular signalling
AU6059099A (en) * 1998-09-25 2000-04-17 Children's Medical Center Corporation Short peptides which selectively modulate the activity of protein kinases
GB9902696D0 (en) * 1999-02-09 1999-03-31 Medical Res Council Screening methods

Also Published As

Publication number Publication date
US20020137141A1 (en) 2002-09-26
WO2002048336A2 (fr) 2002-06-20
US20020115173A1 (en) 2002-08-22
WO2002048336A3 (fr) 2003-03-13

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