AU2002228798A1 - Transgenic mice containing perk protein kinase gene disruptions - Google Patents
Transgenic mice containing perk protein kinase gene disruptionsInfo
- Publication number
- AU2002228798A1 AU2002228798A1 AU2002228798A AU2879802A AU2002228798A1 AU 2002228798 A1 AU2002228798 A1 AU 2002228798A1 AU 2002228798 A AU2002228798 A AU 2002228798A AU 2879802 A AU2879802 A AU 2879802A AU 2002228798 A1 AU2002228798 A1 AU 2002228798A1
- Authority
- AU
- Australia
- Prior art keywords
- protein kinase
- transgenic mice
- kinase gene
- mice containing
- gene disruptions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 101150086096 Eif2ak3 gene Proteins 0.000 title 1
- 241000699660 Mus musculus Species 0.000 title 1
- 238000011830 transgenic mouse model Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/072—Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/20—Animal model comprising regulated expression system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Environmental Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biodiversity & Conservation Biology (AREA)
- Biochemistry (AREA)
- Animal Husbandry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24667600P | 2000-11-07 | 2000-11-07 | |
| US60/246,676 | 2000-11-07 | ||
| US31101801P | 2001-08-08 | 2001-08-08 | |
| US60/311,018 | 2001-08-08 | ||
| US32476501P | 2001-09-24 | 2001-09-24 | |
| US60/324,765 | 2001-09-24 | ||
| US32614801P | 2001-09-28 | 2001-09-28 | |
| US60/326,148 | 2001-09-28 | ||
| PCT/US2001/046457 WO2002037957A2 (en) | 2000-11-07 | 2001-11-07 | Transgenic mice containing perk protein kinase gene disruptions |
| US10/005,983 US20020116730A1 (en) | 2000-11-07 | 2001-11-07 | Transgenic mice containing PERK protein kinase gene disruptions |
| US10/005,983 | 2001-11-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2002228798A1 true AU2002228798A1 (en) | 2002-05-21 |
Family
ID=27533146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002228798A Abandoned AU2002228798A1 (en) | 2000-11-07 | 2001-11-07 | Transgenic mice containing perk protein kinase gene disruptions |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US20020116730A1 (en) |
| AU (1) | AU2002228798A1 (en) |
| WO (1) | WO2002037957A2 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7884260B2 (en) * | 2005-06-14 | 2011-02-08 | University Of Chicago | Cell-based screen for agents useful for reducing neuronal demyelination or promoting neuronal remyelination |
| US8053627B2 (en) * | 2005-06-14 | 2011-11-08 | University Of Chicago | Methods for treating demyelination disorders |
| US7423194B2 (en) * | 2005-06-14 | 2008-09-09 | University Of Chicago | Animal models for demyelination disorders |
| WO2011146748A1 (en) * | 2010-05-21 | 2011-11-24 | New York University | Method of treating cancer by inhibition of protein kinase-like endoplasmic reticulum protein kinase |
-
2001
- 2001-11-07 US US10/005,983 patent/US20020116730A1/en not_active Abandoned
- 2001-11-07 WO PCT/US2001/046457 patent/WO2002037957A2/en not_active Ceased
- 2001-11-07 AU AU2002228798A patent/AU2002228798A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20020116730A1 (en) | 2002-08-22 |
| WO2002037957A2 (en) | 2002-05-16 |
| WO2002037957A3 (en) | 2003-07-24 |
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