AU2002214007A1 - Substituted 3.4-dihydro-pyrimido(1,2-A)pyrimidines and 3.4-dihydropyrazino(1,2-A)pyrimidines - Google Patents

Substituted 3.4-dihydro-pyrimido(1,2-A)pyrimidines and 3.4-dihydropyrazino(1,2-A)pyrimidines

Info

Publication number: AU2002214007A1
Authority: AU; Australia
Prior art keywords: pyrimidines; dihydropyrazino; pyrimido; dihydro; substituted
Prior art date: 2000-10-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2002214007A

Inventor

Matthias Gerlach

Utz-Peter Jagusch

Corinna Maul

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Gruenenthal GmbH

Original Assignee

Gruenenthal GmbH

Chemie Gruenenthal GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-13

Filing date

2001-10-10

Publication date

2002-04-22

2001-10-10 Application filed by Gruenenthal GmbH, Chemie Gruenenthal GmbH filed Critical Gruenenthal GmbH

2002-04-22 Publication of AU2002214007A1 publication Critical patent/AU2002214007A1/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AU2002214007A 2000-10-13 2001-10-10 Substituted 3.4-dihydro-pyrimido(1,2-A)pyrimidines and 3.4-dihydropyrazino(1,2-A)pyrimidines Abandoned AU2002214007A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE10050661A DE10050661A1 (en)	2000-10-13	2000-10-13	New substituted 3,4-dihydro-pyrimido(1,2-a)pyrimidine and 3,4-dihydro-pyrazino(1,2-a)pyrimidine derivatives useful for the treatment of pain, urinary incontinence, pruritis, tinnitus and diarrhea
DE10050661		2000-10-13
PCT/EP2001/011702 WO2002030934A1 (en)	2000-10-13	2001-10-10	Substituted 3.4-dihydro-pyrimido[1,2-a]pyrimidines and 3.4-dihydropyrazino[1,2-a]pyrimidines

Publications (1)

Publication Number	Publication Date
AU2002214007A1 true AU2002214007A1 (en)	2002-04-22

Family

ID=7659596

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2002214007A Abandoned AU2002214007A1 (en)	2000-10-13	2001-10-10	Substituted 3.4-dihydro-pyrimido(1,2-A)pyrimidines and 3.4-dihydropyrazino(1,2-A)pyrimidines

Country Status (25)

Country	Link
US (1)	US7226924B2 (en)
EP (1)	EP1325010B1 (en)
JP (1)	JP2004511485A (en)
KR (1)	KR20030036923A (en)
CN (1)	CN1243753C (en)
AR (1)	AR035496A1 (en)
AT (1)	ATE294180T1 (en)
AU (1)	AU2002214007A1 (en)
BR (1)	BR0114735A (en)
CA (1)	CA2425685A1 (en)
DE (2)	DE10050661A1 (en)
EC (1)	ECSP034554A (en)
ES (1)	ES2239168T3 (en)
HU (1)	HUP0302606A3 (en)
IL (1)	IL155379A0 (en)
MX (1)	MXPA03003199A (en)
NO (1)	NO20031588L (en)
NZ (1)	NZ525651A (en)
PE (1)	PE20020477A1 (en)
PL (1)	PL361777A1 (en)
PT (1)	PT1325010E (en)
RU (1)	RU2003113965A (en)
SK (1)	SK4152003A3 (en)
WO (1)	WO2002030934A1 (en)
ZA (1)	ZA200303634B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2006065703A1 (en)	2004-12-13	2006-06-22	Sunesis Pharmaceuticals, Inc.	Pyrido pyrimidinones, dihydro pyrimido pyrimidinones and pteridinones useful as raf kinase inhibitors
US20070155738A1 (en)	2005-05-20	2007-07-05	Alantos Pharmaceuticals, Inc.	Heterobicyclic metalloprotease inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3558618A (en) *	1968-04-01	1971-01-26	Dow Chemical Co	Novel 4h-pyrazino(1,2-a)pyrimidine-4-ones
GB1347493A (en) *	1971-02-11	1974-02-27	Aspro Nicholas Ltd	Benzazine derivatives
HU178910B (en) *	1977-08-19	1982-07-28	Chinoin Gyogyszer Es Vegyeszet	Process for preparing 2,3-disubstituted-4-oxo-4h-pyrido/1,2-a/-pyrimidines
JP2668259B2 (en) *	1988-02-18	1997-10-27	塩野義製薬株式会社	Heterocyclic compounds and anti-ulcer agents
FI94531C (en) *	1990-03-13	1995-09-25	Ime Intermed Enterpris Sa	Process for Preparing Pharmaceutically Active 1,3,4,6,7,8-Hexahydro-2H-Pyrimido (1,2-a) Pyrimidine Derivatives
IT1263804B (en) *	1993-01-22	1996-09-03	Luso Farmaco Inst	PYRIMIDINONIC DERIVATIVES MELT WITH NITROGEN HETEROCYCLES ACTIVATED IN II ANTAGONIST
CA2206080A1 (en) *	1995-09-28	1997-04-03	Otsuka Pharmaceutical Factory, Inc.	Analgesic composition_of pryazolo{1,5-a}pyrimidine derivatives

2000
- 2000-10-13 DE DE10050661A patent/DE10050661A1/en not_active Withdrawn
2001
- 2001-10-09 AR ARP010104730A patent/AR035496A1/en not_active Application Discontinuation
- 2001-10-10 AT AT01982417T patent/ATE294180T1/en active
- 2001-10-10 MX MXPA03003199A patent/MXPA03003199A/en active IP Right Grant
- 2001-10-10 IL IL15537901A patent/IL155379A0/en unknown
- 2001-10-10 SK SK415-2003A patent/SK4152003A3/en unknown
- 2001-10-10 NZ NZ525651A patent/NZ525651A/en unknown
- 2001-10-10 EP EP01982417A patent/EP1325010B1/en not_active Expired - Lifetime
- 2001-10-10 CN CNB018171591A patent/CN1243753C/en not_active Expired - Fee Related
- 2001-10-10 PT PT01982417T patent/PT1325010E/en unknown
- 2001-10-10 DE DE50106048T patent/DE50106048D1/en not_active Expired - Lifetime
- 2001-10-10 WO PCT/EP2001/011702 patent/WO2002030934A1/en not_active Ceased
- 2001-10-10 ES ES01982417T patent/ES2239168T3/en not_active Expired - Lifetime
- 2001-10-10 CA CA002425685A patent/CA2425685A1/en not_active Abandoned
- 2001-10-10 AU AU2002214007A patent/AU2002214007A1/en not_active Abandoned
- 2001-10-10 RU RU2003113965/04A patent/RU2003113965A/en not_active Application Discontinuation
- 2001-10-10 PL PL01361777A patent/PL361777A1/en not_active Application Discontinuation
- 2001-10-10 HU HU0302606A patent/HUP0302606A3/en unknown
- 2001-10-10 BR BR0114735-8A patent/BR0114735A/en not_active IP Right Cessation
- 2001-10-10 JP JP2002534320A patent/JP2004511485A/en not_active Withdrawn
- 2001-10-10 KR KR10-2003-7005149A patent/KR20030036923A/en not_active Withdrawn
- 2001-10-12 PE PE2001001013A patent/PE20020477A1/en not_active Application Discontinuation
2003
- 2003-04-08 NO NO20031588A patent/NO20031588L/en unknown
- 2003-04-09 US US10/409,614 patent/US7226924B2/en not_active Expired - Fee Related
- 2003-04-11 EC EC2003004554A patent/ECSP034554A/en unknown
- 2003-05-12 ZA ZA200303634A patent/ZA200303634B/en unknown

Also Published As

Publication number	Publication date
ATE294180T1 (en)	2005-05-15
CN1243753C (en)	2006-03-01
PE20020477A1 (en)	2002-06-29
NO20031588D0 (en)	2003-04-08
PL361777A1 (en)	2004-10-04
MXPA03003199A (en)	2004-03-18
BR0114735A (en)	2003-10-14
EP1325010A1 (en)	2003-07-09
WO2002030934A1 (en)	2002-04-18
IL155379A0 (en)	2003-11-23
JP2004511485A (en)	2004-04-15
NZ525651A (en)	2004-10-29
PT1325010E (en)	2005-08-31
ZA200303634B (en)	2004-08-12
US20030220322A1 (en)	2003-11-27
HUP0302606A3 (en)	2007-03-28
ECSP034554A (en)	2003-05-26
KR20030036923A (en)	2003-05-09
NO20031588L (en)	2003-04-08
DE10050661A1 (en)	2002-04-18
RU2003113965A (en)	2004-12-10
CA2425685A1 (en)	2003-04-11
ES2239168T3 (en)	2005-09-16
DE50106048D1 (en)	2005-06-02
CN1469879A (en)	2004-01-21
HUP0302606A2 (en)	2004-07-28
US7226924B2 (en)	2007-06-05
SK4152003A3 (en)	2003-10-07
EP1325010B1 (en)	2005-04-27
AR035496A1 (en)	2004-06-02
HK1056558A1 (en)	2004-02-20

Publication	Publication Date	Title
ZA200207676B (en)	2003-09-25	Imidazopyrimidine derivatives and triazolopyrimidine derivatives.
IL210398A0 (en)	2011-03-31	Novel triazolo (4, 5 - d) pyrimidine
PH12000002783B1 (en)	2006-02-21	Pyrazolo[4,3-D] pyrimidine derivatives.
AU4163197A (en)	1998-03-19	Nonclassical pyrrolo{2,3-d}pyrimidine antifolates
ZA200205097B (en)	2004-01-26	N-(5,7-dimethoxy[1,2,4]triazolo[1,5-A]pyrimidin-2-yl) arylsulfonamide compounds and their use as herbicides.
SI1430057T1 (en)	2006-02-28	Substituted 2-pyridinyl-6,7,8,9-tetrahydropyrimido 1,2-a)pyrimidin-4-one and 7-pyridinyl-2,3-dihydroimidazo 1,2-a)pyrimidin-5(1h)one derivatives
AU2002231676A1 (en)	2002-07-01	Triazolopyrimidines
AU2001250376A1 (en)	2001-09-24	Dihydroimidazo(2,1-b)thiazole and dihydro-5h-thiazolo(3,2-a)pyrimidines as antidepressant agents
AU1224902A (en)	2002-03-13	2-pyridinyl-6,7,8,9-tetrahydropyrimido(1,2-a)pyrimidin-4-one and 7-pyridinyl-2,3-dihydroimidazo(1,2-a)pyrimidin-5(1H)one derivatives
MXPA00007634A (en)	2003-09-10	NOVEL TRIAZOLO(4,5-d.
PL353366A1 (en)	2003-11-17	Pyrazolo[4,3-d]pyrimidines
MXPA03004498A (en)	2003-09-05	Use of pyrazolo[4,3-d]pyrimidines.
MXPA03004907A (en)	2003-09-05	Use of pyrazolo[4,3-d]pyrimidines.
AU2002214007A1 (en)	2002-04-22	Substituted 3.4-dihydro-pyrimido(1,2-A)pyrimidines and 3.4-dihydropyrazino(1,2-A)pyrimidines
AU2002210526A1 (en)	2002-06-27	Substituted 3.4-dihydro-pyrido[1,2-A]pyrimidines
AU2002222344A1 (en)	2002-07-08	Triazolopyrimidines
AU2003274993A1 (en)	2004-05-04	Pyrrolo(1,2-b)pyridazine compounds and their uses
SI1325010T1 (en)	2005-10-31	Substituted 3.4-dihydro-pyrimido (1,2-a)pyrimidines and 3.4-dihydropyrazino (1,2-a)pyrimidines
PL361915A1 (en)	2004-10-04	Substituted 3.4-dihydro-pyrido[1,2-a]pyrimidines
AU2001285905A1 (en)	2002-03-13	6,7-dihydro-pyrrolo(3,4-b)pyridin-5-ones with an anticonvulsive action and methods for producing the same
AU2002325550A1 (en)	2003-03-18	(1,2,4)triazolo(1,5-a)pyrimidine derivative
AU2001282124A1 (en)	2002-03-13	2,5-dihydro-pyrazolo(3,4-D)pyrimidin-4-ones with an anticonvulsive action and methods for producing the same
SI1210349T1 (en)	2003-06-30	PYRAZOLO 4,3-d)PYRIMIDINES
GC0000099A (en)	2005-06-29	Pyrazolo Ä1,5-BÜ pyridazine derivatives.
AU2002244935A1 (en)	2002-10-15	8-thiazolyl(1,2,4)triazolo(1,5-c)pyrimidine derivative

Legal Events

Date	Code	Title	Description
2008-05-08	MK4	Application lapsed section 142(2)(d) - no continuation fee paid for the application