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AU2002211370A1 - Inhibition of tgf-beta and uses thereof - Google Patents

Inhibition of tgf-beta and uses thereof

Info

Publication number
AU2002211370A1
AU2002211370A1 AU2002211370A AU1137002A AU2002211370A1 AU 2002211370 A1 AU2002211370 A1 AU 2002211370A1 AU 2002211370 A AU2002211370 A AU 2002211370A AU 1137002 A AU1137002 A AU 1137002A AU 2002211370 A1 AU2002211370 A1 AU 2002211370A1
Authority
AU
Australia
Prior art keywords
tgf
inhibition
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002211370A
Other languages
English (en)
Inventor
James M Mason
Siamak Tabibzadeh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Feinstein Institutes for Medical Research
Original Assignee
North Shore Long Island Jewish Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by North Shore Long Island Jewish Research Institute filed Critical North Shore Long Island Jewish Research Institute
Publication of AU2002211370A1 publication Critical patent/AU2002211370A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1841—Transforming growth factor [TGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2002211370A 2000-10-05 2001-10-03 Inhibition of tgf-beta and uses thereof Abandoned AU2002211370A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/679,971 2000-10-05
US09/679,971 US6649588B1 (en) 2000-10-05 2000-10-05 Inhibition of TGF-β and uses thereof
PCT/US2001/030872 WO2002029105A1 (fr) 2000-10-05 2001-10-03 Inhibition du tgf-$g(b) et utilisations associees

Publications (1)

Publication Number Publication Date
AU2002211370A1 true AU2002211370A1 (en) 2002-04-15

Family

ID=24729125

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002211370A Abandoned AU2002211370A1 (en) 2000-10-05 2001-10-03 Inhibition of tgf-beta and uses thereof

Country Status (3)

Country Link
US (1) US6649588B1 (fr)
AU (1) AU2002211370A1 (fr)
WO (1) WO2002029105A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294662B1 (en) 1996-08-27 2001-09-25 University Of South Florida Nucleic acids encoding an endometrial bleeding associated factor (ebaf)
US6683156B1 (en) * 1996-08-27 2004-01-27 University Of South Florida Method for diagnosing selected adenocarcinomas
US8106001B2 (en) * 1996-08-27 2012-01-31 University Of South Florida Diagnostic markers of human female infertility
US7211644B1 (en) * 1996-08-27 2007-05-01 University Of South Florida Diagnostic markers of human female infertility
US20060099576A1 (en) * 2000-12-14 2006-05-11 Siamak Tabibzadeh Method for diagnosing a pre-neoplastic or neoplastic lesion in transitional epithelial cells
AU2003297460A1 (en) * 2002-12-19 2004-07-14 Scios, Inc. TREATMENT OF OBESITY AND ASSOCIATED CONDITIONS WITH TGF-Beta INHIBITORS
JP5110877B2 (ja) * 2003-06-02 2012-12-26 ワイス・エルエルシー 神経筋障害を処置するための、コルチコステロイドと組み合わせたミオスタチン（ｇｄｆ８）インヒビターの使用
US20090042780A1 (en) * 2004-05-20 2009-02-12 Acceleron Pharma Inc Modified TGF-Beta Superfamily Polypeptides and Related Methods
EP1899369A2 (fr) * 2005-07-01 2008-03-19 Acceleron Pharma Inc. Gene lefty, derives du gene lefty et leurs utilisations
EP1992360A4 (fr) * 2006-02-01 2010-02-17 Univ Tokyo Utilisation en association d'un inhibiteur de signal tgf-beta et d'un agent antitumeur
US8106004B2 (en) * 2006-07-28 2012-01-31 Children's Memorial Hospital Methods of inhibiting tumor cell aggressiveness using the microenvironment of human embryonic stem cells
US7666423B2 (en) * 2006-07-28 2010-02-23 Children's Memorial Hospital Methods of inhibiting tumor cell aggressiveness using the microenvironment of human embryonic stem cells
WO2009029656A1 (fr) * 2007-08-27 2009-03-05 Auxagen, Inc. Procédés d'inhibition de tgf-β
WO2010033507A1 (fr) * 2008-09-16 2010-03-25 St. Louis University Procédé d'amélioration de signalisation tgf-bêta
BR112021011898A2 (pt) * 2018-12-20 2021-09-08 Chong Kun Dang Pharmaceutical Corp. Proteína de fusão compreendendo variantes de proteína lefty a humana e uso da mesma

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981483A (en) 1994-05-04 1999-11-09 Mount Sinai Hospital Corporation Compositions comprising modulators of cytokines of the TGF-β superfamily
US5916751A (en) 1996-08-27 1999-06-29 University Of South Florida Method for the diagnosis of selected adenocarcinomas

Also Published As

Publication number Publication date
WO2002029105A9 (fr) 2003-02-13
WO2002029105A1 (fr) 2002-04-11
US6649588B1 (en) 2003-11-18

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