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AU2002241664A1 - Use of matrix metalloproteinase peptide substrate to lower the rate of extracellular matrix turnover - Google Patents

Use of matrix metalloproteinase peptide substrate to lower the rate of extracellular matrix turnover

Info

Publication number
AU2002241664A1
AU2002241664A1 AU2002241664A AU2002241664A AU2002241664A1 AU 2002241664 A1 AU2002241664 A1 AU 2002241664A1 AU 2002241664 A AU2002241664 A AU 2002241664A AU 2002241664 A AU2002241664 A AU 2002241664A AU 2002241664 A1 AU2002241664 A1 AU 2002241664A1
Authority
AU
Australia
Prior art keywords
rate
peptide substrate
turnover
matrix
extracellular matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002241664A
Other languages
English (en)
Inventor
Kevin P. Mcgrath
Stephen Quirk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kimberly Clark Worldwide Inc
Original Assignee
Kimberly Clark Worldwide Inc
Kimberly Clark Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kimberly Clark Worldwide Inc, Kimberly Clark Corp filed Critical Kimberly Clark Worldwide Inc
Publication of AU2002241664A1 publication Critical patent/AU2002241664A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2002241664A 2000-12-29 2001-12-21 Use of matrix metalloproteinase peptide substrate to lower the rate of extracellular matrix turnover Abandoned AU2002241664A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75307800A 2000-12-29 2000-12-29
US09/753,078 2000-12-29
PCT/US2001/049272 WO2002053172A2 (fr) 2000-12-29 2001-12-21 Utilisation de substrats peptidiques de metalloproteases matricielles pour reduire la vitesse du renouvellement de la matrice extracellulaire

Publications (1)

Publication Number Publication Date
AU2002241664A1 true AU2002241664A1 (en) 2002-07-16

Family

ID=25029062

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002241664A Abandoned AU2002241664A1 (en) 2000-12-29 2001-12-21 Use of matrix metalloproteinase peptide substrate to lower the rate of extracellular matrix turnover

Country Status (2)

Country Link
AU (1) AU2002241664A1 (fr)
WO (1) WO2002053172A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003299187A1 (en) * 2002-10-01 2004-04-23 Johnson And Johnson Medical Limited Controlled release therapeutic wound dressings
DE102005007468A1 (de) * 2005-02-16 2006-08-31 Beiersdorf Ag Kovalent gebundene Wirkkomplexe, aus denen Stress-aktivierbare Hautenzyme einen Wirkstoff freisetzen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4466919A (en) * 1982-12-16 1984-08-21 Monsanto Company Peptide substrates for mammalian collagenase
FR2546164B1 (fr) * 1983-05-16 1987-07-17 Centre Nat Rech Scient Nouveaux derives de peptides, leur preparation et leur application comme inhibiteurs de l'elastase
US5612194A (en) * 1989-06-23 1997-03-18 Trustees Of The University Of Pennsylvania Methods of producing effective recombinant serine protease inhibitors and uses of these inhibitors
US5618790A (en) * 1990-10-05 1997-04-08 Queen's University At Kingston Protease mediated drug delivery system
US5534496A (en) * 1992-07-07 1996-07-09 University Of Southern California Methods and compositions to enhance epithelial drug transport
US6413530B1 (en) * 1999-04-21 2002-07-02 University Of Florida Research Foundation, Inc. Pesticidal peptides
WO2001046220A2 (fr) * 1999-12-22 2001-06-28 Polymun Scientific Immunbiologische Forschung Gmbh Oligopeptides bioactifs
WO2002038108A2 (fr) * 2000-11-03 2002-05-16 The J. David Gladstone Institutes Procedes de traitement des maladies liees a l'apolipoproteine e

Also Published As

Publication number Publication date
WO2002053172A2 (fr) 2002-07-11
WO2002053172A3 (fr) 2004-02-26

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase