|
ATE396266T1
(en)
*
|
2000-07-28 |
2008-06-15 |
Ulrich Wissenbach |
TRP8 CANCER MARKER
|
|
AU2002336574A1
(en)
*
|
2001-09-17 |
2003-04-01 |
Millennium Pharmaceuticals, Inc. |
Methods of using 5433, a human calcium channel family member
|
|
US7452675B2
(en)
*
|
2002-01-25 |
2008-11-18 |
The Queen's Medical Center |
Methods of screening for TRPM4b modulators
|
|
WO2003087158A2
(en)
*
|
2002-04-16 |
2003-10-23 |
Bayer Healthcare Ag |
Regulation of human transient receptor potential channel
|
|
EP1578371A4
(en)
*
|
2002-08-19 |
2009-05-20 |
Genentech Inc |
Compositions and methods for the diagnosis and treatment of tumor
|
|
CN104998273A
(en)
|
2003-11-06 |
2015-10-28 |
西雅图基因公司 |
Monomethylvaline compounds capable of coupling to ligands
|
|
CA2567520A1
(en)
|
2004-06-01 |
2005-12-15 |
Genentech, Inc. |
Maytansinoid-antibody conjugates
|
|
US20100111856A1
(en)
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
|
EP3088004B1
(en)
|
2004-09-23 |
2018-03-28 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
|
US8148083B2
(en)
*
|
2006-05-25 |
2012-04-03 |
The Queen's Medical Center |
Methods of screening for TRPM4 modulators of insulin secretion
|
|
US8638228B2
(en)
|
2007-02-02 |
2014-01-28 |
Hartford Fire Insurance Company |
Systems and methods for sensor-enhanced recovery evaluation
|
|
CA2809819A1
(en)
|
2009-09-09 |
2011-03-17 |
Centrose, Llc |
Extracellular targeted drug conjugates
|
|
HRP20130953T1
(en)
|
2010-04-15 |
2013-11-22 |
Spirogen Sàrl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
CA2799540A1
(en)
|
2010-06-08 |
2011-12-15 |
Genentech, Inc. |
Cysteine engineered antibodies and conjugates
|
|
EP2640727B1
(en)
|
2010-11-17 |
2015-05-13 |
Genentech, Inc. |
Alaninyl maytansinol antibody conjugates
|
|
MX2013013054A
(en)
|
2011-05-12 |
2014-02-20 |
Genentech Inc |
Multiple reaction monitoring lc-ms/ms method to detect therapeutic antibodies in animal samples using framework signature peptides.
|
|
PL2750713T3
(en)
|
2011-10-14 |
2016-03-31 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
WO2013130093A1
(en)
|
2012-03-02 |
2013-09-06 |
Genentech, Inc. |
Biomarkers for treatment with anti-tubulin chemotherapeutic compounds
|
|
DK2839860T3
(en)
|
2012-10-12 |
2019-06-17 |
Medimmune Ltd |
Pyrrolobenzodiazepines and their conjugates
|
|
MX364329B
(en)
|
2012-10-12 |
2019-04-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates.
|
|
PL2906251T3
(en)
|
2012-10-12 |
2018-02-28 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-anti-cd22 antibody conjugates
|
|
ES2680153T3
(en)
|
2012-10-12 |
2018-09-04 |
Adc Therapeutics Sa |
Anti-PSMA-pyrrolobenzodiazepine antibody conjugates
|
|
WO2014057119A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
|
WO2014057120A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
|
DK2906253T3
(en)
|
2012-10-12 |
2018-10-22 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine anti-PSMA antibody conjugates
|
|
EA031585B1
(en)
|
2012-12-21 |
2019-01-31 |
Медимьюн Лимитед |
Pyrrolobenzodiazepines and conjugates thereof
|
|
CN105246894A
(en)
|
2012-12-21 |
2016-01-13 |
斯皮罗根有限公司 |
Asymmetric pyrrolobenzodiazepine dimers for the treatment of proliferative and autoimmune diseases
|
|
NZ710745A
(en)
|
2013-03-13 |
2019-03-29 |
Genentech Inc |
Pyrrolobenzodiazepines and conjugates thereof
|
|
ES2687439T3
(en)
|
2013-03-13 |
2018-10-25 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
CN105142674B
(en)
|
2013-03-13 |
2018-11-13 |
麦迪穆有限责任公司 |
Pyrrolobenzodiazepines and their conjugates
|
|
BR112016002829A2
(en)
|
2013-08-12 |
2017-09-19 |
Genentech Inc |
COMPOUND AND PROCESS FOR PREPARING ANTIBODY-DRUG CONJUGATE COMPOUND, PHARMACEUTICAL COMPOSITION, CANCER TREATMENT METHOD, CANCER TREATMENT KIT, DRUG LINKER INTERMEDIATE, CBI DIMER DRUG MOUNT AND COMPOUND
|
|
US9956299B2
(en)
|
2013-10-11 |
2018-05-01 |
Medimmune Limited |
Pyrrolobenzodiazepine—antibody conjugates
|
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
US10010624B2
(en)
|
2013-10-11 |
2018-07-03 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
US9950078B2
(en)
|
2013-10-11 |
2018-04-24 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
MX371092B
(en)
|
2013-12-16 |
2020-01-16 |
Genentech Inc |
Peptidomimetic compounds and antibody-drug conjugates thereof.
|
|
JP6980384B2
(en)
|
2013-12-16 |
2021-12-15 |
ジェネンテック, インコーポレイテッド |
1- (Chloromethyl) -2,3-dihydro-1H-benzo [E] indole dimer antibody-drug conjugate compound, and methods of use and treatment
|
|
CN107106700B
(en)
|
2013-12-16 |
2020-10-30 |
基因泰克公司 |
Peptidomimetic compounds and antibody-drug conjugates thereof
|
|
CN106687141A
(en)
|
2014-09-10 |
2017-05-17 |
麦迪穆有限责任公司 |
Pyrrolobenzodiazepines and conjugates thereof
|
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
JP6622293B2
(en)
|
2014-09-12 |
2019-12-18 |
ジェネンテック, インコーポレイテッド |
Anthracycline disulfide intermediates, antibody-drug conjugates, and methods
|
|
EP3388449A3
(en)
|
2014-09-12 |
2018-10-24 |
F. Hoffmann-La Roche AG |
Cysteine engineered antibodies and conjugates
|
|
KR20170067771A
(en)
|
2014-09-17 |
2017-06-16 |
제넨테크, 인크. |
Pyrrolobenzodiazepines and antibody disulfide conjugates thereof
|
|
CN107148285B
(en)
|
2014-11-25 |
2022-01-04 |
Adc治疗股份有限公司 |
Pyrrolobenzodiazepine-antibody conjugates
|
|
AU2015358532C1
(en)
|
2014-12-03 |
2020-10-29 |
Genentech, Inc. |
Quaternary amine compounds and antibody-drug conjugates thereof
|
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
|
MA43345A
(en)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
PYRROLOBENZODIAZEPINE ANTIBODY-DRUG CONJUGATES AND METHODS OF USE
|
|
MA43354A
(en)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
CONJUGATE DRUG CONJUGATES WITH CLOUDY DISULPHIDE
|
|
MA45326A
(en)
|
2015-10-20 |
2018-08-29 |
Genentech Inc |
CALICHEAMICIN-ANTIBODY-DRUG CONJUGATES AND METHODS OF USE
|
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
CN108700598A
(en)
|
2016-03-25 |
2018-10-23 |
豪夫迈·罗氏有限公司 |
The drug of the total antibody of multichannel and antibody conjugate quantifies measuring method
|
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
CN109152843A
(en)
|
2016-05-20 |
2019-01-04 |
豪夫迈·罗氏有限公司 |
PROTAC antibody conjugates and methods of using the same
|
|
CN109313200B
(en)
|
2016-05-27 |
2022-10-04 |
豪夫迈·罗氏有限公司 |
Bioanalytical methods for characterizing site-specific antibody-drug conjugates
|
|
US10639378B2
(en)
|
2016-06-06 |
2020-05-05 |
Genentech, Inc. |
Silvestrol antibody-drug conjugates and methods of use
|
|
CN109689111B
(en)
|
2016-08-11 |
2024-04-05 |
基因泰克公司 |
Pyrrolobenzodiazepine prodrugs and antibody conjugates thereof
|
|
EP3522933B1
(en)
|
2016-10-05 |
2021-12-15 |
F. Hoffmann-La Roche AG |
Methods for preparing antibody drug conjugates
|
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
|
BR112019016373B1
(en)
|
2017-02-08 |
2022-01-25 |
Medimmune Limited |
Antibody-drug conjugate that binds to axl, composition and pharmaceutical composition comprising the same and therapeutic use of said conjugate
|
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
|
ES2926144T3
(en)
|
2017-04-18 |
2022-10-24 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
|
JP7408396B2
(en)
|
2017-04-20 |
2024-01-05 |
アーデーセー セラピューティクス ソシエテ アノニム |
combination therapy
|
|
PL3638373T3
(en)
|
2017-06-14 |
2025-04-14 |
Adc Therapeutics Sa |
Dosing regimens for anti-CD19 ADC administration
|
|
EP3668874B1
(en)
|
2017-08-18 |
2021-12-22 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
|
US10301319B2
(en)
|
2017-09-20 |
2019-05-28 |
Ph Pharma Co., Ltd. |
Thailanstatin analogs
|
|
GB201803342D0
(en)
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
GB201814281D0
(en)
|
2018-09-03 |
2018-10-17 |
Femtogenix Ltd |
Cytotoxic agents
|
|
CN113056287A
(en)
|
2018-10-24 |
2021-06-29 |
豪夫迈·罗氏有限公司 |
Conjugated chemical degradation inducers and methods of use
|
|
JP2022513198A
(en)
|
2018-12-10 |
2022-02-07 |
ジェネンテック, インコーポレイテッド |
Photocrosslinkable peptide for site-specific conjugation to Fc-containing proteins
|
|
GB201901197D0
(en)
|
2019-01-29 |
2019-03-20 |
Femtogenix Ltd |
G-A Crosslinking cytotoxic agents
|
|
MX2021010477A
(en)
|
2019-03-15 |
2021-10-01 |
Medimmune Ltd |
Azetidobenzodiazepine dimers and conjugates comprising them for use in the treatment of cancer.
|
|
JP2024541058A
(en)
|
2021-11-03 |
2024-11-06 |
ハンジョウ ディーエーシー バイオテック シーオー.,エルティディ. |
Specific conjugation of antibodies
|
|
TW202432187A
(en)
|
2022-12-23 |
2024-08-16 |
美商建南德克公司 |
Cereblon degrader conjugates, and uses thereof
|
|
WO2024220546A2
(en)
|
2023-04-17 |
2024-10-24 |
Peak Bio, Inc. |
Antibodies and antibody-drug conjugates and methods of use and synthetic processes and intermediates
|