AU2001237633A1 - Method of identifying modulators of presenilin - Google Patents
Method of identifying modulators of presenilinInfo
- Publication number
- AU2001237633A1 AU2001237633A1 AU2001237633A AU3763301A AU2001237633A1 AU 2001237633 A1 AU2001237633 A1 AU 2001237633A1 AU 2001237633 A AU2001237633 A AU 2001237633A AU 3763301 A AU3763301 A AU 3763301A AU 2001237633 A1 AU2001237633 A1 AU 2001237633A1
- Authority
- AU
- Australia
- Prior art keywords
- presenilin
- identifying modulators
- modulators
- identifying
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 102000015499 Presenilins Human genes 0.000 title 1
- 108010050254 Presenilins Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Neurology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Neurosurgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0005894.1A GB0005894D0 (en) | 2000-03-10 | 2000-03-10 | Assay |
| GB0005894 | 2000-03-10 | ||
| PCT/GB2001/001057 WO2001067109A1 (en) | 2000-03-10 | 2001-03-09 | Method of identifying modulators of presenilin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001237633A1 true AU2001237633A1 (en) | 2001-09-17 |
Family
ID=9887438
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001237633A Abandoned AU2001237633A1 (en) | 2000-03-10 | 2001-03-09 | Method of identifying modulators of presenilin |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20030113811A1 (en) |
| EP (1) | EP1259821A1 (en) |
| AU (1) | AU2001237633A1 (en) |
| GB (1) | GB0005894D0 (en) |
| WO (1) | WO2001067109A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6929919B2 (en) | 2000-09-01 | 2005-08-16 | The Governing Council Of The University Of Toronto | Proteins related to schizophrenia and uses thereof |
| GB0024086D0 (en) * | 2000-10-02 | 2000-11-15 | Inpharmatica Ltd | Proteinase |
| ES2300852T3 (en) * | 2004-01-29 | 2008-06-16 | Cellzome Ag | TREATMENT OF NEUROGENERATIVE DISEASES THROUGH THE USE OF GPR49. |
| US7851228B2 (en) | 2006-03-31 | 2010-12-14 | The Regents Of The University Of California | Methods for screening agents that modulate presenilin activity and A-β production |
| US8129334B2 (en) | 2006-03-31 | 2012-03-06 | The Regents Of The University Of California | Methods and compositions for treating neurodegenerative disorders and Alzheimer'S disease and improving normal memory |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9608657D0 (en) * | 1996-04-26 | 1996-07-03 | Smithkline Beecham Plc | Novel treatment |
| AU3650600A (en) * | 1999-04-01 | 2000-10-23 | Governing Council Of The University Of Toronto, The | A presenilin associated membrane protein and uses thereof |
-
2000
- 2000-03-10 GB GBGB0005894.1A patent/GB0005894D0/en not_active Ceased
-
2001
- 2001-03-09 US US10/221,254 patent/US20030113811A1/en not_active Abandoned
- 2001-03-09 EP EP01910050A patent/EP1259821A1/en not_active Withdrawn
- 2001-03-09 AU AU2001237633A patent/AU2001237633A1/en not_active Abandoned
- 2001-03-09 WO PCT/GB2001/001057 patent/WO2001067109A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20030113811A1 (en) | 2003-06-19 |
| WO2001067109A1 (en) | 2001-09-13 |
| GB0005894D0 (en) | 2000-05-03 |
| EP1259821A1 (en) | 2002-11-27 |
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