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AU2001231901A1 - Cell and tissue culture device with controlled culture fluid circulation - Google Patents

Cell and tissue culture device with controlled culture fluid circulation

Info

Publication number
AU2001231901A1
AU2001231901A1 AU2001231901A AU3190101A AU2001231901A1 AU 2001231901 A1 AU2001231901 A1 AU 2001231901A1 AU 2001231901 A AU2001231901 A AU 2001231901A AU 3190101 A AU3190101 A AU 3190101A AU 2001231901 A1 AU2001231901 A1 AU 2001231901A1
Authority
AU
Australia
Prior art keywords
gas
culture
cell
chamber
fluid circulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001231901A
Inventor
Leila-Ouassila Sarem Damerdji
Farzin Sarem
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU2001231901A1 publication Critical patent/AU2001231901A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/38—Caps; Covers; Plugs; Pouring means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/14—Pressurized fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Immunology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

A cell and tissue culture device comprises a closed pressurization circuit (2) able to deliver a selected gas under a selected pressure, at least a culture chamber (6) accommodating means (13) for supporting at least a deformable membrane (14) forming in chamber (6) an interface between first (17) and second (16) portions with variable complementary volumes, wherein the first portion (17) is configured for receiving cells and/or tissues to be grown for being supplied with culture fluid by a first tank (8), and said second portion (16) is configured for being supplied with gas by the pressurization circuit (2) and for discharging at least a portion of this gas. In addition, it comprises control means (3,4) capable of determining, according to selected criteria relating to the type of culture to be achieved, the gas to be fed into the second portion (16), its pressure and the time for feeding in this gas, and of controlling access to the first and second portions of the chamber (6) so as to control together the shape of the membrane (14), the culture fluid supply and the flow of this fluid in the first portion.
AU2001231901A 2000-01-17 2001-01-15 Cell and tissue culture device with controlled culture fluid circulation Abandoned AU2001231901A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0000547A FR2803852B1 (en) 2000-01-17 2000-01-17 CELL AND TISSUE CULTURE DEVICE WITH CONTROLLED CULTURE FLUID CIRCULATION
FR0000547 2000-01-17
PCT/FR2001/000122 WO2001053451A1 (en) 2000-01-17 2001-01-15 Cell and tissue culture device with controlled culture fluid circulation

Publications (1)

Publication Number Publication Date
AU2001231901A1 true AU2001231901A1 (en) 2001-07-31

Family

ID=8845987

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001231901A Abandoned AU2001231901A1 (en) 2000-01-17 2001-01-15 Cell and tissue culture device with controlled culture fluid circulation

Country Status (8)

Country Link
US (1) US6576458B1 (en)
EP (1) EP1250417B1 (en)
AT (1) ATE262583T1 (en)
AU (1) AU2001231901A1 (en)
CA (1) CA2397600A1 (en)
DE (1) DE60102447T2 (en)
FR (1) FR2803852B1 (en)
WO (1) WO2001053451A1 (en)

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EP1421173A2 (en) * 2001-08-30 2004-05-26 Arbomedics GmbH Method and device for the in vitro cultivation of cells
DE10249903B4 (en) * 2002-10-22 2007-10-11 Cytonet Gmbh & Co. Kg Mechanical bioreactor
DE10307487A1 (en) * 2003-02-21 2004-09-09 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Methods and devices for the injury-free movement of a probe through biological cell material
WO2006124672A2 (en) * 2005-05-12 2006-11-23 University Of Alabama In Huntsville Apparatus and method for incubating cell cultures
US9637715B2 (en) 2005-07-07 2017-05-02 Emd Millipore Corporation Cell culture and invasion assay method and system
US9354156B2 (en) 2007-02-08 2016-05-31 Emd Millipore Corporation Microfluidic particle analysis method, device and system
US9388374B2 (en) 2005-07-07 2016-07-12 Emd Millipore Corporation Microfluidic cell culture systems
US8257964B2 (en) * 2006-01-04 2012-09-04 Cell ASIC Microwell cell-culture device and fabrication method
WO2007008609A2 (en) 2005-07-07 2007-01-18 The Regents Of The University Of California Methods and apparatus for cell culture array
US7745209B2 (en) * 2005-07-26 2010-06-29 Corning Incorporated Multilayered cell culture apparatus
US7745210B2 (en) * 2006-06-30 2010-06-29 Corning Incorporated Fluid flow diverter for cell culture vessel
FR2906258B1 (en) * 2006-09-22 2008-12-19 Maco Pharma Sa METHOD FOR RENEWING A BIOLOGICAL MEDIUM IN WHICH CELLS ARE IN SUSPENSION
US7897379B2 (en) * 2007-02-26 2011-03-01 Corning Incorporated Device and method for reducing bubble formation in cell culture
US9309491B2 (en) 2007-05-29 2016-04-12 Corning Incorporated Cell culture apparatus for co-culture of cells
EP2245453B1 (en) 2008-01-03 2016-10-05 EMD Millipore Corporation Microfluidic cell culture array system for automated assays and methods of operation
DE602008002545D1 (en) * 2008-02-01 2010-10-28 Eppendorf Ag Culture plate with flap for side ventilation
JP5666131B2 (en) * 2008-02-22 2015-02-12 コバレントマテリアル株式会社 Cell culture module
AT506826B1 (en) * 2008-05-23 2010-03-15 Greiner Bio One Gmbh BIOREACTOR AND METHOD FOR CULTURING CELLS AND FABRICS
US20120276622A1 (en) * 2009-05-08 2012-11-01 Chang Gung University Apparatus and method for high-throughput micro-cell culture with mechanical stimulation
KR101131303B1 (en) * 2009-06-08 2012-03-30 한국과학기술원 Device and system for culturing cells and method of culturing cells using the same
TW201111501A (en) * 2009-09-29 2011-04-01 Univ Chang Gung High throughput cell culture system capable of providing mechanical force pressing stimulation
DE102009057698A1 (en) * 2009-12-03 2011-06-09 Martin-Luther-Universität Halle-Wittenberg Two-chamber culture system with elastic, porous membrane for uniaxial mechanical stimulation of epithelial cells and epithelial cell aggregates for the testing of endogenous and exogenous factors
US9353342B2 (en) 2010-01-21 2016-05-31 Emd Millipore Corporation Cell culture and gradient migration assay methods and devices
KR101075032B1 (en) * 2010-02-26 2011-10-21 한국과학기술원 Cell cultivation device and cell cultivation apparatus comprising the same
US9388379B2 (en) 2011-02-25 2016-07-12 Empire Technology Development Llc Dynamically alterable cell support
US10526572B2 (en) 2011-04-01 2020-01-07 EMD Millipore Corporaticn Cell culture and invasion assay method and system
GB201108165D0 (en) * 2011-05-16 2011-06-29 Kirkstall Ltd Bioreactor chamber and method
WO2013082612A1 (en) 2011-12-03 2013-06-06 Emd Millipore Corporation Micro-incubation systems for microfluidic cell culture and methods
SG11201502926TA (en) 2012-10-26 2015-05-28 Massachusetts Inst Technology Humidity control in chemical reactors
CN104870629A (en) * 2012-10-26 2015-08-26 麻省理工学院 Control of carbon dioxide levels and pH in small volume reactors
US10479973B2 (en) 2013-08-23 2019-11-19 Massachuesetts Institute Of Technology Small volume bioreactors with substantially constant working volumes and associated systems and methods
DE102014001615B3 (en) * 2014-02-10 2015-05-28 Yoen Ok Roth Device for the cultivation of adherent cells
CN106148178B (en) * 2015-04-02 2019-10-29 复旦大学附属华山医院 A kind of culture systems and its construction method of the static killing curve for anti-anaerobic agent
EP3998335A3 (en) 2015-05-08 2022-07-27 Biomagnetic Solutions LLC Apparatus and method for immunomagnetic cell separation
CN106281998B (en) * 2015-05-29 2020-04-24 复旦大学附属华山医院 Anaerobic in-vitro dynamic pharmacokinetics/pharmacodynamics model system and construction method
US10227556B2 (en) 2015-09-04 2019-03-12 Wayne State University Cell culture devices for biomimetic and pathomimetic cell cultures
WO2018149795A1 (en) * 2017-02-15 2018-08-23 Ifom - Fondazione Istituto Firc Di Oncologia Molecolare Cell stretching device
US11413378B2 (en) * 2018-05-08 2022-08-16 Biomagnetic Solutions Llc Rigid chamber for cell separation from a flexible disposable bag
CN109810900B (en) * 2019-03-12 2024-01-12 华道(上海)生物医药有限公司 Totally-enclosed cell culture gas control system
FR3143627B1 (en) * 2022-12-15 2024-11-01 Commissariat Energie Atomique Cell culture device with mechanical stimulation function
US12397296B2 (en) * 2024-02-07 2025-08-26 Flow Health Services Incorporated Systems and methods for motile sperm determination

Family Cites Families (4)

* Cited by examiner, † Cited by third party
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US4647539A (en) * 1985-05-24 1987-03-03 Endotronics, Inc. Method and apparatus for growing cells in vitro
FR2690926B1 (en) * 1992-05-06 1995-08-04 Lvmh Rech VARIABLE VOLUME REACTOR DEVICE AND CELL CULTURE METHOD.
DE4437717C1 (en) * 1994-10-21 1996-07-04 Helbing & Partner Main fermenter for producing biogas and process for producing biogas and digestate
US6037141A (en) * 1998-06-04 2000-03-14 Banes; Albert J. Culture compression device

Also Published As

Publication number Publication date
FR2803852B1 (en) 2004-11-05
EP1250417B1 (en) 2004-03-24
WO2001053451A1 (en) 2001-07-26
DE60102447T2 (en) 2005-03-03
FR2803852A1 (en) 2001-07-20
EP1250417A1 (en) 2002-10-23
ATE262583T1 (en) 2004-04-15
DE60102447D1 (en) 2004-04-29
CA2397600A1 (en) 2001-07-26
US6576458B1 (en) 2003-06-10

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