AU2001231287A1 - Pyrrolo-isoquinoline and tetrahydropyrrolo-isoquinoline derivatives and their use as mediators of the 5-ht7 receptor - Google Patents
Pyrrolo-isoquinoline and tetrahydropyrrolo-isoquinoline derivatives and their use as mediators of the 5-ht7 receptorInfo
- Publication number
- AU2001231287A1 AU2001231287A1 AU2001231287A AU3128701A AU2001231287A1 AU 2001231287 A1 AU2001231287 A1 AU 2001231287A1 AU 2001231287 A AU2001231287 A AU 2001231287A AU 3128701 A AU3128701 A AU 3128701A AU 2001231287 A1 AU2001231287 A1 AU 2001231287A1
- Authority
- AU
- Australia
- Prior art keywords
- isoquinoline
- tetrahydropyrrolo
- pyrrolo
- mediators
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- WQTFWIYWEHVZHH-UHFFFAOYSA-N 2,3,4,7-tetrahydro-1h-pyrrolo[2,3-h]isoquinoline Chemical class C1=C2NC=CC2=C2CNCCC2=C1 WQTFWIYWEHVZHH-UHFFFAOYSA-N 0.000 title 1
- 108091005436 5-HT7 receptors Proteins 0.000 title 1
- HVMRAWQBXLQUGB-UHFFFAOYSA-N 7H-pyrrolo[2,3-h]isoquinoline Chemical compound C1=NC=C2C(C=CN3)=C3C=CC2=C1 HVMRAWQBXLQUGB-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Nutrition Science (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49737900A | 2000-02-04 | 2000-02-04 | |
| US09497379 | 2000-02-04 | ||
| PCT/US2001/003430 WO2001057039A1 (en) | 2000-02-04 | 2001-02-02 | Pyrrolo-isoquinoline and tetrahydropyrrolo-isoquinoline derivatives and their use as mediators of the 5-ht7 receptor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001231287A1 true AU2001231287A1 (en) | 2001-08-14 |
Family
ID=23976619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001231287A Abandoned AU2001231287A1 (en) | 2000-02-04 | 2001-02-02 | Pyrrolo-isoquinoline and tetrahydropyrrolo-isoquinoline derivatives and their use as mediators of the 5-ht7 receptor |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1252161A1 (en) |
| JP (1) | JP2003522178A (en) |
| CN (1) | CN1168728C (en) |
| AU (1) | AU2001231287A1 (en) |
| BR (1) | BR0108007A (en) |
| CA (1) | CA2399545A1 (en) |
| MX (1) | MXPA02007521A (en) |
| WO (1) | WO2001057039A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004283196B2 (en) | 2003-09-17 | 2011-08-25 | Janssen Pharmaceutica, N.V. | Fused heterocyclic compounds |
| US7598255B2 (en) | 2005-08-04 | 2009-10-06 | Janssen Pharmaceutica Nv | Pyrimidine compounds as serotonin receptor modulators |
| WO2007053353A2 (en) * | 2005-10-28 | 2007-05-10 | Wyeth | Pyrrolo[2,3-f] and [3,2-f]isoquinolinone derivatives as 5-hydroxytryptamine-6 ligands |
| EP2676954A1 (en) * | 2012-06-19 | 2013-12-25 | Laboratorios del Dr. Esteve S.A. | Heterocyclyl-substituted-phenyl derivatives as vasodilators |
-
2001
- 2001-02-02 CA CA002399545A patent/CA2399545A1/en not_active Abandoned
- 2001-02-02 WO PCT/US2001/003430 patent/WO2001057039A1/en not_active Ceased
- 2001-02-02 BR BR0108007-5A patent/BR0108007A/en not_active IP Right Cessation
- 2001-02-02 JP JP2001557871A patent/JP2003522178A/en active Pending
- 2001-02-02 MX MXPA02007521A patent/MXPA02007521A/en not_active Application Discontinuation
- 2001-02-02 EP EP01903486A patent/EP1252161A1/en not_active Withdrawn
- 2001-02-02 AU AU2001231287A patent/AU2001231287A1/en not_active Abandoned
- 2001-02-02 CN CNB018044328A patent/CN1168728C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1168728C (en) | 2004-09-29 |
| WO2001057039A1 (en) | 2001-08-09 |
| CN1396921A (en) | 2003-02-12 |
| CA2399545A1 (en) | 2001-08-09 |
| BR0108007A (en) | 2002-10-29 |
| MXPA02007521A (en) | 2002-12-13 |
| EP1252161A1 (en) | 2002-10-30 |
| JP2003522178A (en) | 2003-07-22 |
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