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AU2001228854A1 - Alkali metal salt of thiazolidine-2,4-dione derivative - Google Patents

Alkali metal salt of thiazolidine-2,4-dione derivative

Info

Publication number
AU2001228854A1
AU2001228854A1 AU2001228854A AU2885401A AU2001228854A1 AU 2001228854 A1 AU2001228854 A1 AU 2001228854A1 AU 2001228854 A AU2001228854 A AU 2001228854A AU 2885401 A AU2885401 A AU 2885401A AU 2001228854 A1 AU2001228854 A1 AU 2001228854A1
Authority
AU
Australia
Prior art keywords
alkali metal
metal salt
thiazolidine
dione derivative
krp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001228854A
Inventor
Michiro Ohnoda
Kazuo Orita
Noriyuki Yoshida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Publication of AU2001228854A1 publication Critical patent/AU2001228854A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Cosmetics (AREA)

Abstract

The invention provides alkali metal salt of 5-Ä(2,4-dioxothiazolidin-5-yl)methylÜ-2-methoxy-N-ÄÄ4-(trifluoromethyl) phenylÜmethylÜbenzamide and its hydrate. A method has been found, wherein, upon preparing KRP-297, the alkali metal salt of KRP-297 and its hydrate are formed in the reaction system and, after separation and purification, they are freed again from salt, thereby KRP-297 can be advantageously purified industrially for preparation.
AU2001228854A 2000-02-01 2001-01-30 Alkali metal salt of thiazolidine-2,4-dione derivative Abandoned AU2001228854A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000023610 2000-02-01
JP2000-23610 2000-02-01
PCT/JP2001/000598 WO2001057007A1 (en) 2000-02-01 2001-01-30 Alkali metal salt of thiazolidine-2,4-dione derivative

Publications (1)

Publication Number Publication Date
AU2001228854A1 true AU2001228854A1 (en) 2001-08-14

Family

ID=18549739

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001228854A Abandoned AU2001228854A1 (en) 2000-02-01 2001-01-30 Alkali metal salt of thiazolidine-2,4-dione derivative

Country Status (8)

Country Link
US (1) US6818776B2 (en)
EP (1) EP1253145B1 (en)
AT (1) ATE340168T1 (en)
AU (1) AU2001228854A1 (en)
CA (1) CA2401276A1 (en)
DE (1) DE60123213T2 (en)
TW (1) TWI235153B (en)
WO (1) WO2001057007A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1874752A (en) * 2003-11-04 2006-12-06 宝洁公司 Personal cleaning compositions
CA2563063C (en) 2004-04-27 2014-06-03 Wyeth Purification of progesterone receptor modulators

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0742286B2 (en) 1985-08-28 1995-05-10 三共株式会社 Thiazolidine derivative
JPH04270273A (en) 1991-02-25 1992-09-25 Kyorin Pharmaceut Co Ltd Thiazolidine-2,4-dione derivatives and their salts and their production method
JP3053490B2 (en) 1991-02-25 2000-06-19 杏林製薬株式会社 Thiazolidine-2,4-dione derivative, salt thereof and production method
NO302519B1 (en) 1991-12-26 1998-03-16 Sankyo Co Thiazolidine compounds containing a quinone group, and pharmaceutical composition
JP3929512B2 (en) 1995-06-02 2007-06-13 杏林製薬株式会社 N-substituted dioxothiazolidylbenzamide derivative and process for producing the same
JP3144624B2 (en) * 1995-06-02 2001-03-12 杏林製薬株式会社 N-benzyldioxothiazolidylbenzamide derivative and method for producing the same
ID19540A (en) 1997-01-22 1998-07-23 Hoffmann La Roche METHOD OF MAKING BENZOFENON DECREASES
AU4882801A (en) 2000-04-25 2001-11-07 Kyorin Pharmaceutical Co. Ltd. Novel stable crystal of thiazolidinedione derivative and process for producing the same

Also Published As

Publication number Publication date
DE60123213T2 (en) 2007-10-18
ATE340168T1 (en) 2006-10-15
CA2401276A1 (en) 2001-08-09
EP1253145B1 (en) 2006-09-20
US20030013749A1 (en) 2003-01-16
EP1253145A4 (en) 2003-03-26
TWI235153B (en) 2005-07-01
EP1253145A1 (en) 2002-10-30
US6818776B2 (en) 2004-11-16
DE60123213D1 (en) 2006-11-02
WO2001057007A1 (en) 2001-08-09

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