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AU2001228478A1 - Method for the simplified production of (3-chloro-4-fluoro-phenyl)-7-(3-morpholino-4-yl-propoxy)-6-nitro-quinazoline-4-yl)-amine or (3-chloro-4-fluoro-phenyl)-(7-(3-morpholino-4-yl-propoxy)-6-amino-quinazoline-4-yl)-amine. - Google Patents

Method for the simplified production of (3-chloro-4-fluoro-phenyl)-7-(3-morpholino-4-yl-propoxy)-6-nitro-quinazoline-4-yl)-amine or (3-chloro-4-fluoro-phenyl)-(7-(3-morpholino-4-yl-propoxy)-6-amino-quinazoline-4-yl)-amine.

Info

Publication number
AU2001228478A1
AU2001228478A1 AU2001228478A AU2847801A AU2001228478A1 AU 2001228478 A1 AU2001228478 A1 AU 2001228478A1 AU 2001228478 A AU2001228478 A AU 2001228478A AU 2847801 A AU2847801 A AU 2847801A AU 2001228478 A1 AU2001228478 A1 AU 2001228478A1
Authority
AU
Australia
Prior art keywords
quinazoline
morpholino
propoxy
fluoro
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001228478A
Inventor
Dr. Hubert Barth
Simon Schneider
Klaus Steiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Goedecke GmbH
Original Assignee
Goedecke GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goedecke GmbH filed Critical Goedecke GmbH
Publication of AU2001228478A1 publication Critical patent/AU2001228478A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AU2001228478A 2000-02-26 2001-01-23 Method for the simplified production of (3-chloro-4-fluoro-phenyl)-7-(3-morpholino-4-yl-propoxy)-6-nitro-quinazoline-4-yl)-amine or (3-chloro-4-fluoro-phenyl)-(7-(3-morpholino-4-yl-propoxy)-6-amino-quinazoline-4-yl)-amine. Abandoned AU2001228478A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10009267A DE10009267A1 (en) 2000-02-26 2000-02-26 Process for the simple preparation of (3-chloro-4-fluorophenyl) - [7- (3-morpholin-4-yl-propoxy) -6-nitro-quinazolin-4-yl] -amine or (3-chloro -4-fluorophenyl) - [7- (3-morpholin-4-yl-propoxy) -6-amino-quinazolin-4-yl] amine
DE10009267.5 2000-02-26
PCT/EP2001/000695 WO2001062743A2 (en) 2000-02-26 2001-01-23 Method for the simplified production of (3-chloro-4-fluoro-phenyl)-[7-(3-morpholino-4-yl-propoxy)-6-nitro-quinazoline-4-yl]-amine or (3-chloro-4-fluoro-phenyl)-[7-(3-morpholino-4-yl-propoxy)-6-amino-quinazoline-4-yl]-amine

Publications (1)

Publication Number Publication Date
AU2001228478A1 true AU2001228478A1 (en) 2001-09-03

Family

ID=7632648

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001228478A Abandoned AU2001228478A1 (en) 2000-02-26 2001-01-23 Method for the simplified production of (3-chloro-4-fluoro-phenyl)-7-(3-morpholino-4-yl-propoxy)-6-nitro-quinazoline-4-yl)-amine or (3-chloro-4-fluoro-phenyl)-(7-(3-morpholino-4-yl-propoxy)-6-amino-quinazoline-4-yl)-amine.

Country Status (31)

Country Link
US (1) US20030050313A1 (en)
EP (1) EP1265874B1 (en)
JP (1) JP2003524006A (en)
KR (1) KR20030011773A (en)
CN (1) CN1171877C (en)
AR (1) AR027377A1 (en)
AT (1) ATE296810T1 (en)
AU (1) AU2001228478A1 (en)
BR (1) BR0108695A (en)
CA (1) CA2401171A1 (en)
CO (1) CO5280058A1 (en)
DE (2) DE10009267A1 (en)
EA (1) EA005213B1 (en)
EG (1) EG23221A (en)
ES (1) ES2240483T3 (en)
GT (1) GT200100025A (en)
HK (1) HK1054551B (en)
HU (1) HUP0204510A3 (en)
IL (1) IL151206A0 (en)
MX (1) MXPA02008301A (en)
MY (1) MY133846A (en)
PA (1) PA8512701A1 (en)
PE (1) PE20011073A1 (en)
PL (1) PL357774A1 (en)
PT (1) PT1265874E (en)
SV (1) SV2002000320A (en)
TN (1) TNSN01031A1 (en)
UY (1) UY26594A1 (en)
WO (1) WO2001062743A2 (en)
YU (1) YU62502A (en)
ZA (1) ZA200206107B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20040945A1 (en) * 2003-02-05 2004-12-14 Warner Lambert Co PREPARATION OF SUBSTITUTED QUINAZOLINES
WO2006081741A1 (en) * 2005-02-05 2006-08-10 Piaoyang Sun Quinazoline compounds or their medical salts and preparation and medical usage thereof
JP5250901B2 (en) * 2007-02-23 2013-07-31 学校法人慶應義塾 Anilinoquinazoline compounds and uses thereof
US7829574B2 (en) 2008-05-09 2010-11-09 Hutchison Medipharma Enterprises Limited Substituted quinazoline compounds and their use in treating angiogenesis-related diseases
CN105399688A (en) * 2015-12-02 2016-03-16 西南科技大学 Gefitinib preparation method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2174250T5 (en) * 1996-04-12 2010-04-21 Warner-Lambert Company Llc IRREVERSIBLE THYROSINE KINASE INHIBITORS.

Also Published As

Publication number Publication date
PL357774A1 (en) 2004-07-26
CO5280058A1 (en) 2003-05-30
MXPA02008301A (en) 2004-05-14
EA005213B1 (en) 2004-12-30
CN1406232A (en) 2003-03-26
PA8512701A1 (en) 2002-02-21
DE50106391D1 (en) 2005-07-07
ES2240483T3 (en) 2005-10-16
US20030050313A1 (en) 2003-03-13
CN1171877C (en) 2004-10-20
ZA200206107B (en) 2003-07-31
HK1054551A1 (en) 2003-12-05
CA2401171A1 (en) 2001-08-30
EG23221A (en) 2004-08-31
KR20030011773A (en) 2003-02-11
IL151206A0 (en) 2003-04-10
HUP0204510A2 (en) 2003-05-28
GT200100025A (en) 2003-09-22
UY26594A1 (en) 2001-09-28
WO2001062743A3 (en) 2002-03-14
AR027377A1 (en) 2003-03-26
EP1265874A2 (en) 2002-12-18
BR0108695A (en) 2002-12-10
PT1265874E (en) 2005-08-31
EP1265874B1 (en) 2005-06-01
MY133846A (en) 2007-11-30
TNSN01031A1 (en) 2005-11-10
SV2002000320A (en) 2002-06-07
ATE296810T1 (en) 2005-06-15
HUP0204510A3 (en) 2003-07-28
JP2003524006A (en) 2003-08-12
EA200200885A1 (en) 2003-02-27
PE20011073A1 (en) 2001-12-16
YU62502A (en) 2005-03-15
WO2001062743A2 (en) 2001-08-30
HK1054551B (en) 2005-06-03
DE10009267A1 (en) 2001-08-30

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