AU2001298029A1 - Derivatives of the (3s, 4ar, 6s, 8ar) 6-phenylamino-1, 2, 3, 4, 4a, 5, 6, 7, 8, 8a-decahydro isoquinoline-3-carboxylic acid as excitatory amino acid receptor antagonists for the treatment of neurological disorders and neurodegenerative diseases - Google Patents
Derivatives of the (3s, 4ar, 6s, 8ar) 6-phenylamino-1, 2, 3, 4, 4a, 5, 6, 7, 8, 8a-decahydro isoquinoline-3-carboxylic acid as excitatory amino acid receptor antagonists for the treatment of neurological disorders and neurodegenerative diseasesInfo
- Publication number
- AU2001298029A1 AU2001298029A1 AU2001298029A AU2001298029A AU2001298029A1 AU 2001298029 A1 AU2001298029 A1 AU 2001298029A1 AU 2001298029 A AU2001298029 A AU 2001298029A AU 2001298029 A AU2001298029 A AU 2001298029A AU 2001298029 A1 AU2001298029 A1 AU 2001298029A1
- Authority
- AU
- Australia
- Prior art keywords
- phenylamino
- derivatives
- treatment
- receptor antagonists
- neurodegenerative diseases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- SJNYWIUSVOXVTH-NEBZKDRISA-N C1(=CC=CC=C1)N[C@@H]1C[C@@H]2C[C@H](NC[C@@H]2CC1)C(=O)O Chemical compound C1(=CC=CC=C1)N[C@@H]1C[C@@H]2C[C@H](NC[C@@H]2CC1)C(=O)O SJNYWIUSVOXVTH-NEBZKDRISA-N 0.000 title 1
- 229940123511 Excitatory amino acid receptor antagonist Drugs 0.000 title 1
- 208000012902 Nervous system disease Diseases 0.000 title 1
- 208000025966 Neurological disease Diseases 0.000 title 1
- 230000004770 neurodegeneration Effects 0.000 title 1
- 208000015122 neurodegenerative disease Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01500003 | 2001-01-05 | ||
| EP01500003.7 | 2001-01-05 | ||
| PCT/US2001/045858 WO2003024934A2 (en) | 2001-01-05 | 2001-12-19 | Derivatives of the (3s, 4ar, 6s, 8ar) 6-phenylamino-1, 2, 3, 4, 4a, 5, 6, 7, 8, 8a-decahydro isoquinoline-3-carboxylic acid as excitatory amino acid receptor antagonists for the treatment of neurological disorders and neurodegenerative diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001298029A1 true AU2001298029A1 (en) | 2003-04-01 |
Family
ID=8183455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001298029A Abandoned AU2001298029A1 (en) | 2001-01-05 | 2001-12-19 | Derivatives of the (3s, 4ar, 6s, 8ar) 6-phenylamino-1, 2, 3, 4, 4a, 5, 6, 7, 8, 8a-decahydro isoquinoline-3-carboxylic acid as excitatory amino acid receptor antagonists for the treatment of neurological disorders and neurodegenerative diseases |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1351689A2 (en) |
| AU (1) | AU2001298029A1 (en) |
| WO (1) | WO2003024934A2 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003091243A1 (en) | 2002-04-26 | 2003-11-06 | Eli Lilly And Company | Ester derivatives of a decahydroisoquinoline-3-carboxylic acid as analgestics |
| JP5238506B2 (en) * | 2005-10-06 | 2013-07-17 | エグゼリクシス， インコーポレイテッド | Pyridopyrimidinone inhibitors of PIM-1 and / or PIM-3 |
-
2001
- 2001-12-19 EP EP01274482A patent/EP1351689A2/en not_active Withdrawn
- 2001-12-19 WO PCT/US2001/045858 patent/WO2003024934A2/en not_active Ceased
- 2001-12-19 AU AU2001298029A patent/AU2001298029A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003024934A2 (en) | 2003-03-27 |
| EP1351689A2 (en) | 2003-10-15 |
| WO2003024934A3 (en) | 2003-07-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |