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AU2001295206A1 - Substituted caprolactam carbonates and ethers and their use as anti-tumor agents - Google Patents

Substituted caprolactam carbonates and ethers and their use as anti-tumor agents

Info

Publication number
AU2001295206A1
AU2001295206A1 AU2001295206A AU9520601A AU2001295206A1 AU 2001295206 A1 AU2001295206 A1 AU 2001295206A1 AU 2001295206 A AU2001295206 A AU 2001295206A AU 9520601 A AU9520601 A AU 9520601A AU 2001295206 A1 AU2001295206 A1 AU 2001295206A1
Authority
AU
Australia
Prior art keywords
ethers
tumor agents
compounds
substituted caprolactam
carbonates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001295206A
Inventor
Kenneth Walter Bair
Frederick Ray Kinder Jr.
Richard William Versace
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of AU2001295206A1 publication Critical patent/AU2001295206A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12Nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

The present invention relates to certain substituted caporlactam carbonate and ether compounds of following formula (I): pharmaceutical compositions containing said compounds, the use of said compounds in treating tumors and to a process for making said compounds.
AU2001295206A 2000-05-11 2001-05-09 Substituted caprolactam carbonates and ethers and their use as anti-tumor agents Abandoned AU2001295206A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56866700A 2000-05-11 2000-05-11
US09/568667 2000-05-11
PCT/EP2001/005263 WO2001085697A1 (en) 2000-05-11 2001-05-09 Substituted caprolactam carbonates and ethers and their use as anti-tumor agents

Publications (1)

Publication Number Publication Date
AU2001295206A1 true AU2001295206A1 (en) 2001-11-20

Family

ID=24272224

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001295206A Abandoned AU2001295206A1 (en) 2000-05-11 2001-05-09 Substituted caprolactam carbonates and ethers and their use as anti-tumor agents

Country Status (11)

Country Link
EP (1) EP1282604B1 (en)
JP (1) JP2003532711A (en)
CN (1) CN1191237C (en)
AT (1) ATE383341T1 (en)
AU (1) AU2001295206A1 (en)
BR (1) BR0110641A (en)
CA (1) CA2405892C (en)
DE (1) DE60132324T2 (en)
ES (1) ES2299515T3 (en)
PT (1) PT1282604E (en)
WO (1) WO2001085697A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0412843A (en) * 2003-07-25 2006-09-26 Novartis Ag substituted lactams and their use as anticancer agents
DE10349669B3 (en) * 2003-10-24 2005-05-25 Aventis Pharma Deutschland Gmbh Bengamide derivatives, process for their preparation and their use
US7153846B2 (en) 2003-10-24 2006-12-26 Sanofi-Aventis Deutschland Gmbh Bengamide derivatives, process for preparing them, and their use
FR2878528B1 (en) * 2004-11-29 2008-05-16 Aventis Pharma Sa 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDES, PREPARATION THEREOF, COMPOSITIONS CONTAINING SAME AND USE THEREOF
FR2878525B1 (en) 2004-11-29 2007-02-23 Aventis Pharma Sa BENGAMIDES HAVING SUBSTITUTED CAPROLACTAM CYCLE, PREPARATION METHOD, COMPOSITIONS CONTAINING SAME AND USE THEREOF
FR2901554B1 (en) * 2006-05-24 2011-04-01 Sanofi Aventis 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDE-BENZAZEPINE, PREPARATION THEREOF, COMPOSITIONS CONTAINING SAME AND USE THEREOF
FR2901556A1 (en) 2006-05-24 2007-11-30 Sanofi Aventis Sa 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDE DERIVATIVES, THEIR PREPARATION, COMPOSITIONS CONTAINING SAME AND USE THEREOF
FR2901555A1 (en) 2006-05-24 2007-11-30 Sanofi Aventis Sa 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDE-BENZOTHIAZEPINE, THEIR PREPARATION, COMPOSITIONS CONTAINING SAME AND USE THEREOF

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4831135A (en) * 1986-06-18 1989-05-16 The Regents Of The University Of California Bengamide anthelmintics
GB9411841D0 (en) * 1994-06-14 1994-08-03 Pharma Mar Sa New antitumoral compounds from jaspis sponge
CO5140099A1 (en) * 1998-11-17 2002-03-22 Novartis Ag CERTAIN SUBSTITUTED CAPROLACTAMAS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND ITS USE IN TUMORS TREATMENT

Also Published As

Publication number Publication date
DE60132324T2 (en) 2008-12-24
CA2405892C (en) 2009-07-07
JP2003532711A (en) 2003-11-05
BR0110641A (en) 2003-03-18
DE60132324D1 (en) 2008-02-21
ATE383341T1 (en) 2008-01-15
CN1429213A (en) 2003-07-09
EP1282604B1 (en) 2008-01-09
CA2405892A1 (en) 2001-11-15
EP1282604A1 (en) 2003-02-12
CN1191237C (en) 2005-03-02
PT1282604E (en) 2008-04-11
WO2001085697A1 (en) 2001-11-15
ES2299515T3 (en) 2008-06-01

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