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AU2001289063A1 - Novel thio derivatives of sordarin as antifungal agents - Google Patents

Novel thio derivatives of sordarin as antifungal agents

Info

Publication number
AU2001289063A1
AU2001289063A1 AU2001289063A AU8906301A AU2001289063A1 AU 2001289063 A1 AU2001289063 A1 AU 2001289063A1 AU 2001289063 A AU2001289063 A AU 2001289063A AU 8906301 A AU8906301 A AU 8906301A AU 2001289063 A1 AU2001289063 A1 AU 2001289063A1
Authority
AU
Australia
Prior art keywords
sordarin
antifungal agents
thio derivatives
novel thio
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001289063A
Inventor
Neelakantan Balasubramanian
Xuhua Du
Michael Serrano-Wu
Denis R. St. Laurent
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of AU2001289063A1 publication Critical patent/AU2001289063A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/44Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/55Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/56Ring systems containing bridged rings
    • C07C2603/86Ring systems containing bridged rings containing four rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2001289063A 2000-09-15 2001-09-14 Novel thio derivatives of sordarin as antifungal agents Abandoned AU2001289063A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23276200P 2000-09-15 2000-09-15
US60232762 2000-09-15
PCT/US2001/028604 WO2002022567A1 (en) 2000-09-15 2001-09-14 Novel thio derivatives of sordarin as antifungal agents

Publications (1)

Publication Number Publication Date
AU2001289063A1 true AU2001289063A1 (en) 2002-03-26

Family

ID=22874466

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001289063A Abandoned AU2001289063A1 (en) 2000-09-15 2001-09-14 Novel thio derivatives of sordarin as antifungal agents

Country Status (3)

Country Link
US (1) US6436930B1 (en)
AU (1) AU2001289063A1 (en)
WO (1) WO2002022567A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8337481B2 (en) 2005-01-25 2012-12-25 Patrick Slater Method for treating otitis externa

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK88496A3 (en) * 1994-11-08 1997-04-09 Glaxo Wellcome Sa Cyclic derivatives, manufacturing process thereof, pharmaceutical compositions containing them and their use antifungal sordaridin derivatives
EP0711783A1 (en) * 1994-11-08 1996-05-15 Glaxo, S.A. Antifungal Sordarin derivatives
US6040463A (en) * 1996-10-07 2000-03-21 Merck & Co., Inc. Sordarin derivatives
EP0929217B1 (en) * 1996-10-07 2004-03-03 Merck & Co., Inc. Sordarin derivatives

Also Published As

Publication number Publication date
WO2002022567A8 (en) 2002-06-20
WO2002022567A1 (en) 2002-03-21
US6436930B1 (en) 2002-08-20
US20020035073A1 (en) 2002-03-21

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