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AU2001286636A1 - Method for assaying the activity of lysosomal enzymes - Google Patents

Method for assaying the activity of lysosomal enzymes

Info

Publication number
AU2001286636A1
AU2001286636A1 AU2001286636A AU8663601A AU2001286636A1 AU 2001286636 A1 AU2001286636 A1 AU 2001286636A1 AU 2001286636 A AU2001286636 A AU 2001286636A AU 8663601 A AU8663601 A AU 8663601A AU 2001286636 A1 AU2001286636 A1 AU 2001286636A1
Authority
AU
Australia
Prior art keywords
assaying
activity
lysosomal enzymes
lysosomal
enzymes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001286636A
Inventor
Nestor A Chamoles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lysometrix Corp
Original Assignee
Lysometrix Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lysometrix Corp filed Critical Lysometrix Corp
Publication of AU2001286636A1 publication Critical patent/AU2001286636A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2001286636A 2000-08-25 2001-08-24 Method for assaying the activity of lysosomal enzymes Abandoned AU2001286636A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22757300P 2000-08-25 2000-08-25
US60/227,573 2000-08-25
US60227573 2000-08-25
PCT/US2001/026259 WO2002018539A2 (en) 2000-08-25 2001-08-24 Method for assaying the activity of lysosomal enzymes

Publications (1)

Publication Number Publication Date
AU2001286636A1 true AU2001286636A1 (en) 2002-03-13

Family

ID=22853625

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001286636A Abandoned AU2001286636A1 (en) 2000-08-25 2001-08-24 Method for assaying the activity of lysosomal enzymes

Country Status (4)

Country Link
US (2) US7563591B2 (en)
AR (1) AR034413A1 (en)
AU (1) AU2001286636A1 (en)
WO (1) WO2002018539A2 (en)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4606712B2 (en) 2003-01-08 2011-01-05 マサチューセッツ インスティテュート オブ テクノロジー 2-O sulfatase compositions and related methods
US7645873B2 (en) 2003-03-20 2010-01-12 The Scripps Research Institute 6″-amino-6″-deoxygalactosylceramides
JP2006335644A (en) * 2005-05-31 2006-12-14 Gifu Univ Endo α-galactosaminidase highly sensitive substrate, method for producing the same, and method of using the same
PT2056842E (en) 2006-04-07 2013-01-24 Univ Chicago Modified-galactosyl ceramide for the treatment of cancerous diseases
WO2008055225A2 (en) * 2006-10-31 2008-05-08 Musc Foundation For Research Development Systems and methods for in vivo measurement of interstitial biological activity, processes and/or compositions
AU2008205410B2 (en) 2007-01-05 2013-10-10 Massachusetts Institute Of Technology Compositions of and methods of using sulfatases from flavobacterium heparinum
US8440392B2 (en) 2007-03-22 2013-05-14 Advanced Liquid Logic Inc. Method of conducting a droplet based enzymatic assay
US8202686B2 (en) 2007-03-22 2012-06-19 Advanced Liquid Logic, Inc. Enzyme assays for a droplet actuator
US8093062B2 (en) 2007-03-22 2012-01-10 Theodore Winger Enzymatic assays using umbelliferone substrates with cyclodextrins in droplets in oil
US8916164B2 (en) * 2007-08-29 2014-12-23 Abivax Methods of enhancing adjuvaticity of vaccine compositions
EP2058011A1 (en) * 2007-11-07 2009-05-13 Wittycell Nkt cell activating gycolipids covalently bound antigens and/or drug
EP2060252A1 (en) * 2007-11-19 2009-05-20 Wittycell New formulation of galactosylceramide derivatives
BRPI0820960B8 (en) * 2007-12-05 2021-05-25 Abivax composition, pharmaceutical composition, and use of the composition
CA2739765A1 (en) * 2008-10-08 2010-04-15 Vincent Serra Vaccine composition for use against influenza
PL2470199T3 (en) 2009-08-28 2019-11-29 Icahn School Med Mount Sinai Dose escalation enzyme replacement therapy for treating acid sphingomyelinase deficiency
MX2010009791A (en) * 2009-09-03 2011-03-17 Kraft Foods Global Brands Llc Method for processing whole muscle meat.
US8536148B2 (en) 2009-09-04 2013-09-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Disabling autophagy as a treatment for lysosomal storage diseases
US8685749B2 (en) 2009-12-02 2014-04-01 Whatman International Limited Methods and systems for processing samples on porous substrates
EP2516669B1 (en) 2009-12-21 2016-10-12 Advanced Liquid Logic, Inc. Enzyme assays on a droplet actuator
WO2012027612A1 (en) * 2010-08-25 2012-03-01 Michael Gelb Mass spectrometric compositions and methods for lysosomal storage disease screening
US9513253B2 (en) 2011-07-11 2016-12-06 Advanced Liquid Logic, Inc. Droplet actuators and techniques for droplet-based enzymatic assays
CN103487414A (en) * 2012-06-14 2014-01-01 北京和信非凡生物技术有限公司 Method, substrate and reagents for alpha-L-iduronidase activity detection
CN102967571A (en) * 2012-12-24 2013-03-13 北京利德曼生化股份有限公司 Liquid single reagent for detecting alpha-L-fucosidase and preparation method thereof
SI3004896T1 (en) 2013-06-07 2020-01-31 Genzyme Corporation Marker for acid sphingomyelinase disorders and uses thereof
KR102279042B1 (en) * 2013-09-05 2021-07-20 유니버시티 오브 워싱턴 Reagents and methods for screening mps i, ii, iiia, iiib, iva, vi, and vii
CA2938498A1 (en) 2014-02-18 2015-08-27 Shire Human Genetic Therapies, Inc. Substrate clearance assays for lysosomal enzymes
US9575064B2 (en) * 2014-09-02 2017-02-21 Perkinelmer Health Sciences, Inc. Methods relating to testing for lysosomal storage disorders
EP3233128A4 (en) * 2014-12-18 2018-05-23 GE Healthcare UK Limited Analyte detection on a solid support by nucleic acid amplification coupled to an immunoassay
CN105486853A (en) * 2015-12-22 2016-04-13 山东博科生物产业有限公司 Alpha-L-fucosidase colorimetric method detection kit
AU2017206687B2 (en) 2016-01-14 2021-12-23 Jamlet MONASELIDZE Differential scanning microcalorimeter device for detecting disease and monitoring therapeutic efficacy
CN106282231B (en) * 2016-09-06 2020-01-03 陕西慧康生物科技有限责任公司 Construction method and application of mucopolysaccharide storage disease type II animal model
CN107014934B (en) * 2017-04-14 2020-12-08 广州金域医学检验中心有限公司 Urine organic acid filter paper quality control product and preparation method thereof
US20220348981A1 (en) * 2019-09-23 2022-11-03 University Of Washington Assay of arylsulfatase a enzymatic activity in dried blood spots by mass spectrometry and fluorometry
CN111678755B (en) * 2020-05-21 2023-09-19 桂林优利特医疗电子有限公司 Tubular quality control object for urine component analyzer and preparation method thereof
CN112301093A (en) * 2020-11-05 2021-02-02 诺道中科(北京)生物科技有限公司 Detection kit for activity of beta-glucocerebrosidase
CN112176026A (en) * 2020-11-06 2021-01-05 诺道中科(北京)生物科技有限公司 Detection kit for alpha-galactosidase activity

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5281522A (en) * 1988-09-15 1994-01-25 Adeza Biomedical Corporation Reagents and kits for determination of fetal fibronectin in a vaginal sample
US5089392A (en) * 1990-03-30 1992-02-18 The United States Of America As Represented By Of The Department Of Health And Human Services Fluorogenic substrates for measurement of lysosomal enzyme activities within intact cells
ATE221203T1 (en) 1992-03-04 2002-08-15 Abbott Lab DETERMINATION OF GLYCOSYLATED HEMOGLOBIN BY ATTENUATION OF FLUORESCENCE
CA2147887A1 (en) * 1992-10-30 1994-05-11 James W. Dennis Method for measuring glycosyltransferase activity
US5538857A (en) 1994-06-01 1996-07-23 Isolab, Inc. Assay for enzyme activity from a red blood sample using a direct microfluorometric assay
US5830912A (en) * 1996-11-15 1998-11-03 Molecular Probes, Inc. Derivatives of 6,8-difluoro-7-hydroxycoumarin

Also Published As

Publication number Publication date
WO2002018539A3 (en) 2002-07-18
US7563591B2 (en) 2009-07-21
US20090325206A1 (en) 2009-12-31
AR034413A1 (en) 2004-02-25
WO2002018539A2 (en) 2002-03-07
US20040166554A1 (en) 2004-08-26

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