AU2001285765A1 - Medium chain fatty acids applicable as antimicrobial agents - Google Patents
Medium chain fatty acids applicable as antimicrobial agentsInfo
- Publication number
- AU2001285765A1 AU2001285765A1 AU2001285765A AU8576501A AU2001285765A1 AU 2001285765 A1 AU2001285765 A1 AU 2001285765A1 AU 2001285765 A AU2001285765 A AU 2001285765A AU 8576501 A AU8576501 A AU 8576501A AU 2001285765 A1 AU2001285765 A1 AU 2001285765A1
- Authority
- AU
- Australia
- Prior art keywords
- acid
- fatty acids
- chain fatty
- medium chain
- antimicrobial agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 150000004667 medium chain fatty acids Chemical class 0.000 title abstract 6
- 239000004599 antimicrobial Substances 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 12
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 abstract 6
- 239000000203 mixture Substances 0.000 abstract 3
- 239000000839 emulsion Substances 0.000 abstract 2
- MNWFXJYAOYHMED-UHFFFAOYSA-N heptanoic acid group Chemical group C(CCCCCC)(=O)O MNWFXJYAOYHMED-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 238000011109 contamination Methods 0.000 abstract 1
- 239000006052 feed supplement Substances 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 239000003053 toxin Substances 0.000 abstract 1
- 231100000765 toxin Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
- A23B2/00—Preservation of foods or foodstuffs, in general
- A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
- A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
- A23B2/729—Organic compounds; Microorganisms; Enzymes
- A23B2/742—Organic compounds containing oxygen
- A23B2/754—Organic compounds containing oxygen containing carboxyl groups
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
- A23B2/00—Preservation of foods or foodstuffs, in general
- A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
- A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
- A23B2/729—Organic compounds; Microorganisms; Enzymes
- A23B2/742—Organic compounds containing oxygen
- A23B2/75—Organic compounds containing oxygen with doubly-bound oxygen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
- A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Birds (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pest Control & Pesticides (AREA)
- Nutrition Science (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Mycology (AREA)
- Environmental Sciences (AREA)
- Epidemiology (AREA)
- Fodder In General (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Feed For Specific Animals (AREA)
Abstract
The present invention relates to the use of one or more C6-C10 medium chain fatty acids (MCFA), salts, derivatives or mixtures or emulsions thereof for the inhibition of microbial contamination, growth and the subsequent toxin production. The MCFA are chosen from the group consisting of caproic (C6) acid, heptanoic (C7) acid, caprylic (C8) acid, nonanoic (C9) acid and capric (C10) acid. The invention further relates to a feed composition for an animal comprising a feed supplement containing one or more medium chain fatty acids (MCFA) chosen from the group consisting of caproic (C6) acid, heptanoic (C7) acid, caprylic (C8) acid, nonanoic (C9) acid and capric (C10) acid, preferably caprylic (C8) acid, and capric (C10) acid, salts, derivatives or mixtures or emulsions thereof.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00870137 | 2000-06-20 | ||
| EP00870137 | 2000-06-20 | ||
| PCT/EP2001/006973 WO2001097799A1 (en) | 2000-06-20 | 2001-06-20 | Medium chain fatty acids applicable as antimicrobial agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001285765A1 true AU2001285765A1 (en) | 2002-01-02 |
Family
ID=8175769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001285765A Abandoned AU2001285765A1 (en) | 2000-06-20 | 2001-06-20 | Medium chain fatty acids applicable as antimicrobial agents |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20030176500A1 (en) |
| EP (1) | EP1294371B2 (en) |
| JP (1) | JP5259905B2 (en) |
| KR (1) | KR20030025933A (en) |
| CN (1) | CN100348183C (en) |
| AT (1) | ATE284687T1 (en) |
| AU (1) | AU2001285765A1 (en) |
| CA (1) | CA2407896A1 (en) |
| DE (1) | DE60107846T3 (en) |
| DK (1) | DK1294371T4 (en) |
| ES (1) | ES2234877T5 (en) |
| PT (1) | PT1294371E (en) |
| WO (1) | WO2001097799A1 (en) |
Families Citing this family (67)
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|---|---|---|---|---|
| US6616942B1 (en) | 1999-03-29 | 2003-09-09 | Soft Gel Technologies, Inc. | Coenzyme Q10 formulation and process methodology for soft gel capsules manufacturing |
| FR2810547B1 (en) * | 2000-06-22 | 2004-01-30 | Pasteur Institut | USE OF C2-C10 ACIDS FOR THE PREVENTION OF NEGATIVE GRAM BACTERIA INFECTIONS |
| CA2444463C (en) * | 2001-04-18 | 2012-03-20 | Prometic Biosciences Inc. | Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors |
| JP2003160486A (en) * | 2001-09-17 | 2003-06-03 | Lion Corp | Oral hair restorer and food and drink containing the hair restorer |
| EP1314358A1 (en) * | 2001-11-21 | 2003-05-28 | N.V. Seghers Nutrition Sciences | Antimicrobial composition for animals |
| AU2003900927A0 (en) * | 2003-02-28 | 2003-03-13 | Biodiem Ltd | Growth promotion method |
| AT502601A1 (en) * | 2003-03-11 | 2007-04-15 | Tulln Zuckerforschung Gmbh | METHOD FOR PRODUCING SUGAR OR SUGAR-CONTAINING PRODUCTS FROM SUGAR-CONTAINING VEGETABLE RAW MATERIALS |
| US7658959B2 (en) * | 2003-06-12 | 2010-02-09 | Cargill, Incorporated | Antimicrobial salt solutions for food safety applications |
| US7883732B2 (en) * | 2003-06-12 | 2011-02-08 | Cargill, Incorporated | Antimicrobial salt solutions for cheese processing applications |
| US7090882B2 (en) * | 2003-06-12 | 2006-08-15 | Cargill, Incorporated | Antimicrobial salt solutions for food safety applications |
| US7588696B2 (en) * | 2003-06-12 | 2009-09-15 | Cargill, Incorporated | Antimicrobial water softener salt and solutions |
| US20080089877A1 (en) * | 2003-08-14 | 2008-04-17 | Udell Ronald G | Super Absorption Coenzyme Q10 |
| US8124072B2 (en) * | 2003-09-29 | 2012-02-28 | Soft Gel Technologies, Inc. | Solubilized CoQ-10 |
| AU2004277951B2 (en) | 2003-09-29 | 2010-11-11 | Soft Gel Technologies, Inc. | Solubilized CoQ-10 |
| ES2523018T3 (en) * | 2004-06-30 | 2014-11-20 | Nutrition Sciences N.V./S.A. | Medium chain fatty acids applicable as anti-microbial agents |
| JP4657653B2 (en) * | 2004-08-24 | 2011-03-23 | 曽田香料株式会社 | Body temperature raising agent |
| DE102004046603A1 (en) * | 2004-09-25 | 2006-03-30 | Goldschmidt Gmbh | Agent for treating microorganisms e.g. mycobacteria and viruses, and for preparing food preservatives and cosmetic formulation, comprises mixture of fatty acid ester of polyol and salts of short chain monocarboxylic acid |
| JP4523519B2 (en) * | 2005-08-22 | 2010-08-11 | 上野製薬株式会社 | Degradation inhibitor for fruits and vegetables and method for inhibiting degradation |
| US8486472B2 (en) * | 2006-01-18 | 2013-07-16 | Cargill, Incorporated | Antimicrobial salt solutions for food safety applications |
| JP5050195B2 (en) * | 2006-02-14 | 2012-10-17 | 国立大学法人 岡山大学 | Neuronal differentiation inducer |
| US8691843B2 (en) | 2006-07-12 | 2014-04-08 | Novus International, Inc. | Antioxidant combinations for use in ruminant feed rations |
| CN101594849A (en) * | 2006-11-17 | 2009-12-02 | 诺华丝国际股份有限公司 | Matrix-embedded compositions with organic acids and fatty acids |
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| CA2593701A1 (en) * | 2007-07-13 | 2009-01-13 | Martin Clement | Free fatty acids for interfering with growth of fusarium graminearum |
| PT2299998T (en) | 2007-11-02 | 2018-04-02 | Prometic Pharma Smt Ltd | Medium-chain length fatty acids and glycerides as nephroprotection agents |
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| EP2215913A1 (en) | 2009-01-23 | 2010-08-11 | Nutreco Nederland B.V. | Animal feed additive and animal feed comprising alkyl esters of medium chain fatty acids, and their use in animal feed |
| HUE028283T2 (en) | 2009-08-06 | 2016-12-28 | Anitox Corp | Water and food preservatives |
| EP2301368A1 (en) * | 2009-09-08 | 2011-03-30 | Mars, Incorporated | Composition for prevention against spoilage by microorganisms and uses and products related thereto |
| BE1019290A5 (en) | 2010-04-14 | 2012-05-08 | Nutrition Sciences Nv Sa | FOOD SUPPLEMENT INCLUDING OLIGOSACCHARIDES AND MEDIUM CHAIN FATTY ACIDS. |
| UA111166C2 (en) | 2010-08-27 | 2016-04-11 | Анітокс Корпорейшн | COMPOSITION AGAINST SALMONELLA TYPHIMURIUM AND METHOD OF ANIMAL FEED PROCESSING |
| WO2013003946A1 (en) * | 2011-07-04 | 2013-01-10 | Contech Enterprises Inc. | Compositions and methods for attracting and stimulating feeding by mice and rats |
| JP2014534967A (en) | 2011-10-20 | 2014-12-25 | アニトックス コーポレーション | Antimicrobial formulation containing pelargonic acid |
| CN102488088A (en) * | 2011-11-14 | 2012-06-13 | 龙岩新奥生物科技有限公司 | Medium-chain fatty glyceride and application thereof in microcapsules |
| HUE053434T2 (en) | 2011-11-30 | 2021-06-28 | Anitox Corp | An antimicrobial mixture of aldehydes, organic acids and esters of organic acids |
| CN110075310A (en) * | 2011-12-20 | 2019-08-02 | 维奥姆治疗有限公司 | For treating the local fluid composition of fungal infection |
| EP2636307B1 (en) | 2012-03-07 | 2015-01-07 | Cargill, Incorporated | The method for production of antimicrobial compostion containing free fatty acids |
| CN104427869A (en) * | 2012-07-06 | 2015-03-18 | 诺维信公司 | Liquid enzyme composition and method for enzyme recovery |
| BR112014029846A2 (en) * | 2012-07-06 | 2017-06-27 | Novozymes As | microbial host cell inactivation method in a fermentation broth |
| RU2630906C2 (en) | 2012-09-13 | 2017-09-14 | Спесиалите Пет Фуд | Application of fat compositions to preserve improved palatability of animals feed for a long time |
| EP3649870A1 (en) * | 2013-10-09 | 2020-05-13 | Nutrition Sciences N.V. | Composition of medium-chain fatty acids and feed supplemented with composition |
| BE1021007B1 (en) | 2013-10-09 | 2014-12-11 | Nutrition Sciences N.V. | COMPOSITION AND FOOD INCLUDING MEDIUM-LONG FATTY ACID CHAIN |
| HUE050907T2 (en) * | 2013-11-13 | 2021-01-28 | Hankkija Oy | Feed supplement containing resin acids |
| US20150305372A1 (en) * | 2014-04-28 | 2015-10-29 | Basf Se | Feed intake of ruminants using green fodder flavors |
| CN104041669B (en) * | 2014-05-23 | 2017-06-23 | 广州英赛特生物技术有限公司 | Capric acid zinc as animal feed additive application |
| EP3220744A4 (en) | 2014-11-19 | 2018-08-01 | Kansas State University Research Foundation | Chemical mitigants in animal feed and feed ingredients |
| WO2016129100A1 (en) * | 2015-02-13 | 2016-08-18 | 油化産業株式会社 | Agent for increasing useful bacteria in animal intestines, and method for improving intestinal environment in livestock in which said agent is used |
| TWI663919B (en) * | 2015-02-16 | 2019-07-01 | 日商油化產業股份有限公司 | Increasing agent for useful bacteria in animal intestines and livestock intestinal environment improvement method using the same |
| CN105410365B (en) * | 2015-12-17 | 2019-06-11 | 浙江大学 | A kind of feed additive that can replace antibiotics and its application |
| CN105724779A (en) * | 2016-02-23 | 2016-07-06 | 广州英赛特生物技术有限公司 | Compound feeding composition and application of compound feeding composition in preparation of animal feed additive |
| CN105746908B (en) * | 2016-02-23 | 2018-08-28 | 广州英赛特生物技术有限公司 | Application of the myristic acid derivative in preparing animal growth promoting agent |
| SE539766C2 (en) * | 2016-05-20 | 2017-11-21 | Perstorp Ab | Animal feed additive effective as broad-spectrum preservative |
| EP3562467B2 (en) | 2016-12-27 | 2023-09-06 | Unilever Global IP Limited | An antimicrobial composition |
| EP3681310B1 (en) * | 2017-09-13 | 2025-02-12 | Rrip, Llc | Compositions and methods for antimicrobial and immune boosting activity |
| CN109503384A (en) * | 2017-09-15 | 2019-03-22 | 魏雪涛 | Gallate-fumaric acid derivatives and its application in terms of beasts, birds and aquatic products animal |
| KR102610200B1 (en) * | 2018-02-12 | 2023-12-06 | 고려대학교 산학협력단 | Antimicrobial composition comprising benzoyl derivatives group and medium chain fatty acid |
| CN109511811A (en) * | 2019-01-29 | 2019-03-26 | 潍坊加易加生物科技有限公司 | One kind is for anti-Short-Chain Fatty Acids essential oil formulation and preparation method thereof and its application |
| CN110122667B (en) * | 2019-05-30 | 2023-06-23 | 河南正通化工有限公司 | Feed antibacterial agent and preparation method thereof |
| CN111011634A (en) * | 2019-12-31 | 2020-04-17 | 广东汇海农牧科技集团有限公司 | Pig feed additive for preventing diarrhea of weaned piglets and pig feed |
| US12234496B1 (en) | 2020-07-22 | 2025-02-25 | Bioveritas, Llc | Systems and processes for obtaining natural preservatives and nutritional supplements |
| KR102442047B1 (en) * | 2020-09-10 | 2022-09-08 | 서울대학교산학협력단 | Fatty acid glyceride compound containing sulfate and amine group, production method and use thereof |
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-
2001
- 2001-06-20 CN CNB018114091A patent/CN100348183C/en not_active Expired - Lifetime
- 2001-06-20 EP EP01965011A patent/EP1294371B2/en not_active Expired - Lifetime
- 2001-06-20 WO PCT/EP2001/006973 patent/WO2001097799A1/en not_active Ceased
- 2001-06-20 AT AT01965011T patent/ATE284687T1/en active
- 2001-06-20 ES ES01965011T patent/ES2234877T5/en not_active Expired - Lifetime
- 2001-06-20 JP JP2002503284A patent/JP5259905B2/en not_active Expired - Fee Related
- 2001-06-20 CA CA002407896A patent/CA2407896A1/en not_active Abandoned
- 2001-06-20 US US10/311,413 patent/US20030176500A1/en not_active Abandoned
- 2001-06-20 AU AU2001285765A patent/AU2001285765A1/en not_active Abandoned
- 2001-06-20 PT PT01965011T patent/PT1294371E/en unknown
- 2001-06-20 DE DE60107846T patent/DE60107846T3/en not_active Expired - Lifetime
- 2001-06-20 KR KR1020027017257A patent/KR20030025933A/en not_active Withdrawn
- 2001-06-20 DK DK01965011.8T patent/DK1294371T4/en active
Also Published As
| Publication number | Publication date |
|---|---|
| DE60107846T3 (en) | 2010-11-04 |
| WO2001097799A1 (en) | 2001-12-27 |
| ES2234877T3 (en) | 2005-07-01 |
| ATE284687T1 (en) | 2005-01-15 |
| EP1294371B2 (en) | 2010-05-26 |
| DE60107846T2 (en) | 2005-12-08 |
| DE60107846D1 (en) | 2005-01-20 |
| JP5259905B2 (en) | 2013-08-07 |
| JP2003535894A (en) | 2003-12-02 |
| PT1294371E (en) | 2005-05-31 |
| EP1294371B1 (en) | 2004-12-15 |
| DK1294371T3 (en) | 2005-04-25 |
| KR20030025933A (en) | 2003-03-29 |
| CA2407896A1 (en) | 2001-12-27 |
| ES2234877T5 (en) | 2010-10-18 |
| DK1294371T4 (en) | 2010-09-20 |
| CN100348183C (en) | 2007-11-14 |
| US20030176500A1 (en) | 2003-09-18 |
| EP1294371A1 (en) | 2003-03-26 |
| CN1437467A (en) | 2003-08-20 |
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