[go: up one dir, main page]

AU2001285157A1 - 5t4 rna in plasma and serum as a marker for neoplastic disease - Google Patents

5t4 rna in plasma and serum as a marker for neoplastic disease

Info

Publication number
AU2001285157A1
AU2001285157A1 AU2001285157A AU8515701A AU2001285157A1 AU 2001285157 A1 AU2001285157 A1 AU 2001285157A1 AU 2001285157 A AU2001285157 A AU 2001285157A AU 8515701 A AU8515701 A AU 8515701A AU 2001285157 A1 AU2001285157 A1 AU 2001285157A1
Authority
AU
Australia
Prior art keywords
rna
serum
plasma
neoplastic disease
marker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001285157A
Inventor
Christopher D. Gocke
Michael S. Kopreski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OncoMEDx Inc
Original Assignee
OncoMEDx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/649,371 external-priority patent/US6794135B1/en
Application filed by OncoMEDx Inc filed Critical OncoMEDx Inc
Publication of AU2001285157A1 publication Critical patent/AU2001285157A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

This invention relates to methods of detecting or inferring the presence of malignant or premalignant cells in a human that express 5T4. Provided are methods for detecting 5T4 RNA in blood, plasma, serum, other bodily fluids, cells, and tissues. The invention thereby provides an aid for the detection, diagnosis, monitoring, treatment, or evaluation of neoplastic disease.
AU2001285157A 2000-08-28 2001-08-21 5t4 rna in plasma and serum as a marker for neoplastic disease Abandoned AU2001285157A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/649,371 2000-08-28
US09/649,371 US6794135B1 (en) 1996-03-26 2000-08-28 Method for detection of 5T4 RNA in plasma or serum
PCT/US2001/026119 WO2002018645A2 (en) 2000-08-28 2001-08-21 5t4 rna in plasma and serum as a marker for neoplastic disease

Publications (1)

Publication Number Publication Date
AU2001285157A1 true AU2001285157A1 (en) 2002-03-13

Family

ID=24604503

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001285157A Abandoned AU2001285157A1 (en) 2000-08-28 2001-08-21 5t4 rna in plasma and serum as a marker for neoplastic disease

Country Status (6)

Country Link
US (2) US20050260594A1 (en)
EP (1) EP1354060B1 (en)
AT (1) ATE498020T1 (en)
AU (1) AU2001285157A1 (en)
DE (1) DE60144027D1 (en)
WO (1) WO2002018645A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060121477A1 (en) * 2002-09-12 2006-06-08 Abraham Hochberg Method for detection of micro-metastasis
US8252528B2 (en) * 2008-06-12 2012-08-28 The Invention Science Fund I, Llc Methods, compositions, and kits for collecting and detecting oligonucleotides
US8614057B2 (en) * 2008-06-12 2013-12-24 The Invention Science Fund I, Llc Methods for collecting and detecting oligonucleotides
US8252529B2 (en) * 2008-06-12 2012-08-28 The Invention Science Fund I, Llc Methods for collecting and detecting oligonucleotides
GB0822836D0 (en) * 2008-12-15 2009-01-21 Oxford Biomedica Ltd Method

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869053A (en) * 1988-03-04 1999-02-09 Cancer Research Campaign Technology, Ltd. 5T4 antigen from human trophoblasts
WO1989007947A1 (en) * 1988-03-04 1989-09-08 Cancer Research Campaign Technology Limited Improvements relating to antigens
AU675774B2 (en) * 1991-10-04 1997-02-20 Children's Hospital Of Philadelphia, The Detecting digeorge syndrome mutations
WO1997035589A1 (en) * 1996-03-26 1997-10-02 Kopreski Michael S Method enabling use of extracellular rna extracted from plasma or serum to detect, monitor or evaluate cancer
US5939262A (en) * 1996-07-03 1999-08-17 Ambion, Inc. Ribonuclease resistant RNA preparation and utilization
GB9704444D0 (en) * 1997-03-04 1997-04-23 Isis Innovation Non-invasive prenatal diagnosis
US6664056B2 (en) * 2000-10-17 2003-12-16 The Chinese University Of Hong Kong Non-invasive prenatal monitoring
FR2839015A1 (en) * 2002-04-29 2003-10-31 Conception & Dev Michelin Sa Flexible non-pneumatic tire comprising a series of articulated joints between supporting elements and interconnecting structure
AU2004205774B2 (en) * 2003-01-17 2006-12-14 The Chinese University Of Hong Kong Circulating mRNA as diagnostic markers for pregnancy-related disorders

Also Published As

Publication number Publication date
WO2002018645A2 (en) 2002-03-07
ATE498020T1 (en) 2011-02-15
DE60144027D1 (en) 2011-03-24
US20080200410A1 (en) 2008-08-21
EP1354060A2 (en) 2003-10-22
US20050260594A1 (en) 2005-11-24
EP1354060B1 (en) 2011-02-09
WO2002018645A3 (en) 2003-07-24

Similar Documents

Publication Publication Date Title
WO2002018652A3 (en) Method for detection of htr and htert telomerase-associated rna in plasma or serum
WO2003028531A3 (en) Detection of tumor rna in plasma and serum
AU2002327308A1 (en) Methods for evaluating pathologic conditions using extracellular rna
WO2002057741A3 (en) Monoclonal antibodies and cell surface antigens for the detection and treatment of small cell lung cancer (sclc)
WO2002054081A3 (en) Proteins, genes and their use for diagnosis and treatment of kidney response
AU2867302A (en) Fluorescence-mediated molecular tomography
WO2002018651A3 (en) Methods for detecting papillomavirus dna in blood plasma and serum
WO2002040634A3 (en) Expression miniarrays and uses thereof
WO2002031507A3 (en) Non-invasive enzyme screen for tissue remodelling-associated conditions
WO2004065583A3 (en) Gene expression markers for breast cancer prognosis
WO2002006526A8 (en) Detection of copy number changes in colon cancer
WO2004071572A3 (en) Gene expression markers for response to egfr inhibitor drugs
WO2002059604A3 (en) Diagnosis and treatment of multiple sclerosis
WO1998045328A3 (en) Compositions and methods for the treatment and diagnosis of breast cancer
NZ338068A (en) Diagnosis of early gastric cancer detecting cyclooxygenase-2 mRNA expression or Cox-2 protein overexpression
AU2002251366A1 (en) Proteins, genes and their use for diagnosis and treatment of breast cancer
WO2003001183A3 (en) Methods for detecting and monitoring cox-2 rna in plasma and serum
AU2002338852A1 (en) Genes and proteins for prevention, prediction, prognosis and therapy of cardiovascular disease
WO2004031414A3 (en) Method for diagnosing prostate cancer
AU2001233913A1 (en) Bcmp 84, a protein associated to breast cancer
AU6583700A (en) Proteins, genes and their use for diagnosis and treatment of breast cancer
AU6630101A (en) Chest piece for stethoscopes, and methods of utilizing stethoscopes for monitoring the physiological conditons of patient
WO2003031942A8 (en) Reagents and methods useful for detecting diseases of the breast
AU6425800A (en) Agents for the diagnosis, prognosis and treatment of malignant diseases
AU2001285157A1 (en) 5t4 rna in plasma and serum as a marker for neoplastic disease