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AU2001284285A1 - A thiazolidinedione derivative and its use as antidiabetic - Google Patents

A thiazolidinedione derivative and its use as antidiabetic

Info

Publication number
AU2001284285A1
AU2001284285A1 AU2001284285A AU8428501A AU2001284285A1 AU 2001284285 A1 AU2001284285 A1 AU 2001284285A1 AU 2001284285 A AU2001284285 A AU 2001284285A AU 8428501 A AU8428501 A AU 8428501A AU 2001284285 A1 AU2001284285 A1 AU 2001284285A1
Authority
AU
Australia
Prior art keywords
compound
antidiabetic
thiazolidinedione derivative
thiazolidinedione
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001284285A
Inventor
Andrew Simon Craig
Michael Millan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of AU2001284285A1 publication Critical patent/AU2001284285A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A novel pharmaceutical compound 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione ethanesulfonate or a solvate thereof, a process for preparing such a compound, a pharmaceutical composition comprising such a compound and the use of such a compound in medicine.
AU2001284285A 2000-09-05 2001-09-05 A thiazolidinedione derivative and its use as antidiabetic Abandoned AU2001284285A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0021784.4A GB0021784D0 (en) 2000-09-05 2000-09-05 Novel pharmaceutical
GB0021784 2000-09-05
PCT/GB2001/003996 WO2002020520A1 (en) 2000-09-05 2001-09-05 A thiazolidinedione derivative and its use as antidiabetic

Publications (1)

Publication Number Publication Date
AU2001284285A1 true AU2001284285A1 (en) 2002-03-22

Family

ID=9898884

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001284285A Abandoned AU2001284285A1 (en) 2000-09-05 2001-09-05 A thiazolidinedione derivative and its use as antidiabetic

Country Status (13)

Country Link
US (1) US20040044043A1 (en)
EP (1) EP1315724B1 (en)
JP (1) JP2004508370A (en)
KR (1) KR100769008B1 (en)
CN (1) CN1239501C (en)
AT (1) ATE310000T1 (en)
AU (1) AU2001284285A1 (en)
CY (1) CY1105354T1 (en)
DE (1) DE60115062T2 (en)
DK (1) DK1315724T3 (en)
ES (1) ES2248385T3 (en)
GB (1) GB0021784D0 (en)
WO (1) WO2002020520A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39384E1 (en) 1993-09-01 2006-11-07 Smithkline Beecham P.L.C. Substituted thiazolidinedione derivatives
KR20040062963A (en) * 2001-11-21 2004-07-09 스미스클라인비이참피이엘시이 5-(4-(2-(n-methyl-n-(2-pyridil)amino)ethoxy)benzyl) thiazolidine-2,4-dione benzenesulfonate, process for its preparation, polymorphs i, ii and iii thereof, and its use as pharmaceutical active ingredient
DE102005034406A1 (en) * 2005-07-22 2007-02-01 Ratiopharm Gmbh New salts of rosiglitazone
US7435741B2 (en) 2006-05-09 2008-10-14 Teva Pharmaceutical Industries, Ltd. 2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate
EP2043744A2 (en) * 2006-07-13 2009-04-08 SmithKline Beecham Corporation Chemical compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
US5741803A (en) * 1992-09-05 1998-04-21 Smithkline Beecham Plc Substituted thiazolidinedionle derivatives
GB9726563D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
GB9726566D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
GB9726568D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical

Also Published As

Publication number Publication date
DE60115062T2 (en) 2006-06-29
KR20030027112A (en) 2003-04-03
HK1057751A1 (en) 2004-04-16
JP2004508370A (en) 2004-03-18
EP1315724A1 (en) 2003-06-04
CN1239501C (en) 2006-02-01
ES2248385T3 (en) 2006-03-16
GB0021784D0 (en) 2000-10-18
DK1315724T3 (en) 2006-02-20
WO2002020520A1 (en) 2002-03-14
CY1105354T1 (en) 2010-03-03
KR100769008B1 (en) 2007-10-22
DE60115062D1 (en) 2005-12-22
CN1471529A (en) 2004-01-28
US20040044043A1 (en) 2004-03-04
EP1315724B1 (en) 2005-11-16
ATE310000T1 (en) 2005-12-15

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