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AU2001284028A1 - Use of ectoin or ectoin derivatives for stabilizing p53 - Google Patents

Use of ectoin or ectoin derivatives for stabilizing p53

Info

Publication number
AU2001284028A1
AU2001284028A1 AU2001284028A AU8402801A AU2001284028A1 AU 2001284028 A1 AU2001284028 A1 AU 2001284028A1 AU 2001284028 A AU2001284028 A AU 2001284028A AU 8402801 A AU8402801 A AU 8402801A AU 2001284028 A1 AU2001284028 A1 AU 2001284028A1
Authority
AU
Australia
Prior art keywords
ectoin
stabilizing
derivatives
ectoin derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001284028A
Inventor
Joachim Bunger
Francois Marchio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of AU2001284028A1 publication Critical patent/AU2001284028A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/001—Preparations for care of the lips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/004—Aftersun preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/06—Preparations for styling the hair, e.g. by temporary shaping or colouring

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001284028A 2000-09-04 2001-08-21 Use of ectoin or ectoin derivatives for stabilizing p53 Abandoned AU2001284028A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10043456A DE10043456A1 (en) 2000-09-04 2000-09-04 Use of ectoin or ectoin derivatives to stabilize p53
DE10043456.8 2000-09-04
PCT/EP2001/009670 WO2002020017A2 (en) 2000-09-04 2001-08-21 Use of ectoin or ectoin derivatives for stabilizing p53

Publications (1)

Publication Number Publication Date
AU2001284028A1 true AU2001284028A1 (en) 2002-03-22

Family

ID=7654866

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001284028A Abandoned AU2001284028A1 (en) 2000-09-04 2001-08-21 Use of ectoin or ectoin derivatives for stabilizing p53

Country Status (6)

Country Link
US (1) US20030199446A1 (en)
EP (1) EP1315498A2 (en)
JP (1) JP2004508332A (en)
AU (1) AU2001284028A1 (en)
DE (1) DE10043456A1 (en)
WO (1) WO2002020017A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005510460A (en) * 2001-08-10 2005-04-21 メディカル リサーチ カウンシル molecule
DE10214257A1 (en) * 2002-03-28 2003-10-16 Merck Patent Gmbh Use of compatible solutes to inhibit the release of ceramides
TWI280136B (en) * 2003-05-30 2007-05-01 Lytone Enterprise Inc Composition containing dipeptide of histidine and alanine for reducing uric acid
JP2006527712A (en) * 2003-06-17 2006-12-07 エフ．ホフマン−ラ　ロシュ　アーゲー Cis-2,4,5-triaryl-imidazoline
US7425638B2 (en) 2003-06-17 2008-09-16 Hoffmann-La Roche Inc. Cis-imidazolines
US20080176209A1 (en) * 2004-04-08 2008-07-24 Biomatrica, Inc. Integration of sample storage and sample management for life science
EP1737573A2 (en) 2004-04-08 2007-01-03 Biomatrica, Inc. Integration of sample storage and sample management for life science
US20060286050A1 (en) * 2005-06-01 2006-12-21 L'oreal Moisturizing lipstick compositions
WO2010132508A2 (en) * 2009-05-11 2010-11-18 Biomatrica, Inc. Compositions and methods for biological sample storage
CA2806670A1 (en) 2010-07-26 2012-02-09 Biomatrica, Inc. Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures
US9845489B2 (en) 2010-07-26 2017-12-19 Biomatrica, Inc. Compositions for stabilizing DNA, RNA and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
EP3249054A1 (en) 2012-12-20 2017-11-29 Biomatrica, INC. Formulations and methods for stabilizing pcr reagents
EP3154338B1 (en) 2014-06-10 2020-01-29 Biomatrica, INC. Stabilization of thrombocytes at ambient temperatures
KR102787387B1 (en) 2015-12-08 2025-03-26 바이오매트리카 인코포레이티드 Reduction of erythrocyte sedimentation rate
US11304968B2 (en) 2018-11-16 2022-04-19 Janssen Pharmaceutica Nv Pharmaceutical compositions comprising a hydroxyethylquercetin glucuronide
US10639294B2 (en) 2018-10-02 2020-05-05 Janssen Pharmaceutica Nv Pharmaceutical compositions comprising a hydroxyethylquercetin glucuronide metabolite

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL100810A (en) * 1992-01-30 1996-12-05 Yeda Res & Dev Pharmaceutical compositions comprising 2-methyl-4-carboxy-5-hydroxy-tetrahydropyrimidine and/or 2-methyl-4-carboxy-tetrahydropyrimidine methods for the isolation and purification of said compounds and substantially pure 2-methyl-4-carboxy-5-hydroxy-3, 4, 5, 6-tetrahydropyrimidine salts 5-ethers and 5-esters thereof
JPH09143167A (en) * 1995-11-17 1997-06-03 Dainippon Pharmaceut Co Ltd Enzyme stabilization method
DE19933463A1 (en) * 1998-07-10 2000-01-13 Beiersdorf Ag Cosmetic or dermatological emulsions having radical scavenging and antioxidant activity, useful e.g. for preventing skin aging and inflammatory reactions
DE19834816A1 (en) * 1998-08-01 2000-02-03 Merck Patent Gmbh Use of ectoin or ectoin derivatives in cosmetic formulations
ES2204640T3 (en) * 1999-06-12 2004-05-01 Bitop Aktiengesellschaft Fur Biotechnische Optimierung PHARMACEUTICAL PREPARED WITH PROTEIN CONTENT.
EP1125583A1 (en) * 2000-02-14 2001-08-22 Bitop Gesellschaft für biotechnische Optimierung MbH Use of compatible solutes as inhibitors of the enzymatic degradation of macromolecular biopolymers
DE10006578C2 (en) * 2000-02-14 2002-10-31 Bitop Ag Use of compatible solutes as inhibitors of the enzymatic degradation of macromolecular biopolymers
DE10014632A1 (en) * 2000-03-24 2001-09-27 Merck Patent Gmbh Protection of stress proteins in the skin using ectoine or its derivatives, is useful in topical skin care or make-up cosmetic compositions for maintaining the defense mechanism of the skin

Also Published As

Publication number Publication date
WO2002020017A2 (en) 2002-03-14
US20030199446A1 (en) 2003-10-23
JP2004508332A (en) 2004-03-18
DE10043456A1 (en) 2002-03-14
WO2002020017A3 (en) 2003-03-13
EP1315498A2 (en) 2003-06-04

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