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AU2001282857A1 - Peptide and polypeptide inhibitors of complement c1s - Google Patents

Peptide and polypeptide inhibitors of complement c1s

Info

Publication number
AU2001282857A1
AU2001282857A1 AU2001282857A AU8285701A AU2001282857A1 AU 2001282857 A1 AU2001282857 A1 AU 2001282857A1 AU 2001282857 A AU2001282857 A AU 2001282857A AU 8285701 A AU8285701 A AU 8285701A AU 2001282857 A1 AU2001282857 A1 AU 2001282857A1
Authority
AU
Australia
Prior art keywords
complement
peptide
polypeptide inhibitors
polypeptide
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001282857A
Other languages
English (en)
Inventor
Brian A. Fox
Paul O Sheppard
Robert R. West
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of AU2001282857A1 publication Critical patent/AU2001282857A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43536—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU2001282857A 2000-06-21 2001-06-18 Peptide and polypeptide inhibitors of complement c1s Abandoned AU2001282857A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21299800P 2000-06-21 2000-06-21
US60/212,998 2000-06-21
PCT/US2001/019405 WO2001098365A2 (fr) 2000-06-21 2001-06-18 Inhibiteurs peptidiques et polypeptidiques du complement c1s

Publications (1)

Publication Number Publication Date
AU2001282857A1 true AU2001282857A1 (en) 2002-01-02

Family

ID=22793322

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001282857A Abandoned AU2001282857A1 (en) 2000-06-21 2001-06-18 Peptide and polypeptide inhibitors of complement c1s

Country Status (5)

Country Link
US (2) US7071299B2 (fr)
EP (1) EP1349874A2 (fr)
AU (1) AU2001282857A1 (fr)
CA (1) CA2413830A1 (fr)
WO (1) WO2001098365A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030211094A1 (en) * 2001-06-26 2003-11-13 Nelsestuen Gary L. High molecular weight derivatives of vitamin k-dependent polypeptides
WO2003007689A2 (fr) 2001-07-20 2003-01-30 Eidgenoessische Technische Hochschule Zurich (Ethz) Compositions et procedes pour l'utilisation d'agents bioactifs derives d'acides sulfates et sulfones
CA2496834C (fr) * 2002-09-06 2014-03-18 Alexion Pharmaceuticals, Inc. Procede de traitement de l'asthme mettant en oeuvre des anticorps en complement du constituant c5
US20050271660A1 (en) 2002-09-06 2005-12-08 Alexion Pharmaceuticals, Inc. Nebulization of monoclonal antibodies for treating pulmonary diseases
US9415102B2 (en) 2002-09-06 2016-08-16 Alexion Pharmaceuticals, Inc. High concentration formulations of anti-C5 antibodies
US7482376B2 (en) * 2003-07-03 2009-01-27 3-Dimensional Pharmaceuticals, Inc. Conjugated complement cascade inhibitors
DE602006010834D1 (de) 2005-03-16 2010-01-14 Janssen Pharmaceutica Nv Neue thiophensulfoximine zur behandlung von komplementvermittelten krankheiten und leiden
CA2819810A1 (fr) * 2010-12-06 2012-06-14 The University Of British Columbia Compositions inhibitrices de granzyme b, methodes et utilisations pour favoriser la cicatrisation
CN110818798A (zh) 2012-10-25 2020-02-21 美国比奥维拉迪维股份有限公司 抗补体C1s抗体和其用途
RS63212B1 (sr) 2012-11-02 2022-06-30 Bioverativ Usa Inc Antikomplementna c1s antitela i njihove primene
EP3193906B1 (fr) * 2014-09-18 2020-11-11 The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of Holy and Undiv. Trinity of Queen Elizabeth near Dublin Utilisation de peptides inhibiteurs de l'il-36 pour le traitement et/ou la réduction de l'inflammation
HUE061076T2 (hu) 2015-04-06 2023-05-28 Bioverativ Usa Inc Humanizált anti-C1s ellenanyagok alkalmazási eljárások
DK3525583T3 (da) 2016-10-12 2025-10-27 Bioverativ Usa Inc Anti-c1s-antistoffer og fremgangsmåder til anvendelse deraf
JP2023548343A (ja) * 2020-11-02 2023-11-16 レアルタ ライフ サイエンシズ インコーポレイテッド ペプチドおよび使用方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9800817D0 (en) * 1998-01-16 1998-03-11 Bio Discovery Ltd Serine protease inhibitors

Also Published As

Publication number Publication date
US20020102256A1 (en) 2002-08-01
WO2001098365A3 (fr) 2003-07-03
CA2413830A1 (fr) 2001-12-27
EP1349874A2 (fr) 2003-10-08
US7071299B2 (en) 2006-07-04
WO2001098365A2 (fr) 2001-12-27
US20050267035A1 (en) 2005-12-01

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