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AU2001282551A1 - Heart muscular cell apoptosis inhibitors and remedies/preventives for heart diseases - Google Patents

Heart muscular cell apoptosis inhibitors and remedies/preventives for heart diseases

Info

Publication number
AU2001282551A1
AU2001282551A1 AU2001282551A AU8255101A AU2001282551A1 AU 2001282551 A1 AU2001282551 A1 AU 2001282551A1 AU 2001282551 A AU2001282551 A AU 2001282551A AU 8255101 A AU8255101 A AU 8255101A AU 2001282551 A1 AU2001282551 A1 AU 2001282551A1
Authority
AU
Australia
Prior art keywords
heart
preventives
remedies
cell apoptosis
apoptosis inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001282551A
Inventor
Tatsuhiko Kaneko
Haruhide Kimura
Seiichi Tanida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of AU2001282551A1 publication Critical patent/AU2001282551A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/041,3-Thiazines; Hydrogenated 1,3-thiazines
    • C07D279/081,3-Thiazines; Hydrogenated 1,3-thiazines condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/101,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/141,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/161,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2001282551A 2000-08-31 2001-08-30 Heart muscular cell apoptosis inhibitors and remedies/preventives for heart diseases Abandoned AU2001282551A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000262757 2000-08-31
JP2000-262757 2000-08-31
PCT/JP2001/007468 WO2002018356A1 (en) 2000-08-31 2001-08-30 Heart muscular cell apoptosis inhibitors and remedies/preventives for heart diseases

Publications (1)

Publication Number Publication Date
AU2001282551A1 true AU2001282551A1 (en) 2002-03-13

Family

ID=18750391

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001282551A Abandoned AU2001282551A1 (en) 2000-08-31 2001-08-30 Heart muscular cell apoptosis inhibitors and remedies/preventives for heart diseases

Country Status (5)

Country Link
US (1) US6794383B2 (en)
EP (1) EP1325918A4 (en)
AU (1) AU2001282551A1 (en)
CA (1) CA2419838A1 (en)
WO (1) WO2002018356A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7399759B2 (en) 2001-09-03 2008-07-15 Takeda Pharmaceutical Company Limited 1, 3-benzothiazinone derivatives and use thereof
US20060034832A1 (en) * 2002-04-26 2006-02-16 Haruhide Kimura Cell death inhibitor
US7659267B2 (en) 2002-12-05 2010-02-09 Takeda Pharmaceutical Company Limited 1,3-Benzothiazinone derivatives, process for producing the same use thereof
JPWO2006132438A1 (en) * 2005-06-09 2009-01-08 武田薬品工業株式会社 1,3-Benzothiazinone derivatives and uses thereof
US9044483B2 (en) 2006-09-22 2015-06-02 Takeda Pharmaceuticals Company Limited Cell death inhibition by macrophage migration inhibitory factor and a binding substance thereto

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470168A (en) * 1967-03-31 1969-09-30 American Home Prod 2-substituted-4h-1,3-benzothiazin-4-one derivatives
IT1254884B (en) * 1992-04-16 1995-10-11 Italfarmaco Spa BENZOSSAZINONI AND BENZOTIAZINONI WITH CARDIOVASCULAR ACTIVITY
US20020022636A1 (en) * 1997-09-03 2002-02-21 Jia-He Li Oxo-substituted compounds, process of making, and compositions and methods for inhibiting parp activity
AU2002220241A1 (en) 2000-12-01 2002-06-11 Iconix Pharmaceuticals, Inc. Parb inhibitors

Also Published As

Publication number Publication date
CA2419838A1 (en) 2003-02-18
US6794383B2 (en) 2004-09-21
US20030186971A1 (en) 2003-10-02
EP1325918A1 (en) 2003-07-09
WO2002018356A1 (en) 2002-03-07
EP1325918A4 (en) 2004-03-10

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