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AU2001280000A1 - Process for preparation of anhydrous azithromycin - Google Patents

Process for preparation of anhydrous azithromycin

Info

Publication number
AU2001280000A1
AU2001280000A1 AU2001280000A AU8000001A AU2001280000A1 AU 2001280000 A1 AU2001280000 A1 AU 2001280000A1 AU 2001280000 A AU2001280000 A AU 2001280000A AU 8000001 A AU8000001 A AU 8000001A AU 2001280000 A1 AU2001280000 A1 AU 2001280000A1
Authority
AU
Australia
Prior art keywords
process according
solvent
compound
water
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001280000A
Other languages
English (en)
Inventor
Anjum Reyaz Khan
Shiva P Singh
Siddiqui Mohammed Jaw Mukarram
Manish Purohit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wockhardt Ltd
Original Assignee
Wockhardt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wockhardt Ltd filed Critical Wockhardt Ltd
Publication of AU2001280000A1 publication Critical patent/AU2001280000A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
AU2001280000A 2000-08-23 2001-08-23 Process for preparation of anhydrous azithromycin Abandoned AU2001280000A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22734100P 2000-08-23 2000-08-23
US60227341 2000-08-23
PCT/IB2001/001523 WO2002015842A2 (en) 2000-08-23 2001-08-23 Process for preparation of anhydrous azithromycin

Publications (1)

Publication Number Publication Date
AU2001280000A1 true AU2001280000A1 (en) 2002-03-04

Family

ID=22852706

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001280000A Abandoned AU2001280000A1 (en) 2000-08-23 2001-08-23 Process for preparation of anhydrous azithromycin

Country Status (10)

Country Link
US (2) US7414114B2 (ja)
EP (1) EP1313749B1 (ja)
JP (1) JP2004506664A (ja)
AT (1) ATE306491T1 (ja)
AU (1) AU2001280000A1 (ja)
CA (1) CA2419873A1 (ja)
DE (1) DE60114028T2 (ja)
NO (1) NO20030772L (ja)
WO (1) WO2002015842A2 (ja)
ZA (1) ZA200301384B (ja)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20020231A2 (en) * 2002-03-18 2003-12-31 Pliva D D ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
ATE320441T1 (de) 2000-07-25 2006-04-15 Silanes Sa De Cv Lab Einstufiges verfahren zur herstellung von 7,16-
CA2419873A1 (en) * 2000-08-23 2002-02-28 Wockhardt Limited Process for preparation of anhydrous azithromycin
EP1390377B1 (en) 2001-05-22 2006-03-08 Pfizer Products Inc. New crystal form of azithromycin
US6861413B2 (en) 2001-05-22 2005-03-01 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
EP1490382A4 (en) * 2002-04-03 2007-09-12 Hanmi Pharm Ind Co Ltd PROCESS FOR PREPARING AZITHROMYXIN AND HYDRATE CRYSTALLINE 9-DEOXO-9A-HOMOERYTHROMYCIN
HRP20020614A2 (en) 2002-07-22 2004-06-30 PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. Rhombic pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a
US7435805B2 (en) * 2003-05-30 2008-10-14 Glaxpsmithkline Istrazivacki O-alkyl macrolide and azalide derivatives and regioselective process for their preparation
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
US7683162B2 (en) 2004-08-30 2010-03-23 Taro Pharmaceutical Industries Limited Process of preparing a crystalline azithromycin monohydrate
EP1976860A2 (en) * 2006-01-12 2008-10-08 Wockhardt Limited Processes for the preparation of azithromycin
MX2011009548A (es) 2009-03-13 2011-12-14 Da Volterra Composiciones y metodos para la eliminacion de bacterias gram-negativas.
US8106111B2 (en) 2009-05-15 2012-01-31 Eastman Chemical Company Antimicrobial effect of cycloaliphatic diol antimicrobial agents in coating compositions
TW201309346A (zh) 2011-01-05 2013-03-01 Hospira Inc 噴霧乾燥萬古黴素
US20130172271A1 (en) * 2012-01-04 2013-07-04 Cynthia Fragale Pharmaceutical Spray Drying
CN103897002A (zh) * 2012-12-31 2014-07-02 菏泽市方明制药有限公司 一种粗品硫氰酸红霉素制备红霉素a9-肟的方法
CN104043104B (zh) 2013-03-15 2018-07-10 浙江创新生物有限公司 含盐酸万古霉素的喷雾干粉及其工业化制备方法

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1100504A (en) 1967-08-16 1968-01-24 Pliva Pharm & Chem Works Erythromycin oxime and 9-amino-3-o-cladinosyl-5-o-desosaminyl-6,11,12-trihydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide
US3736313A (en) 1971-02-26 1973-05-29 Abbott Lab Erythromycin derivatives
US3842068A (en) 1972-06-15 1974-10-15 Abbott Lab 8-epi-erythromycins
YU43116B (en) 1979-04-02 1989-04-30 Pliva Pharm & Chem Works Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
US4331803A (en) 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
YU43006B (en) 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
DE3136679A1 (de) 1981-09-16 1983-03-24 Bayer Ag, 5090 Leverkusen Kationische triazinfarbstoffe, ihre herstellung und verwendung
US4474768A (en) 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
PH19293A (en) 1982-11-15 1986-03-04 Pfizer Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof
US4526889A (en) 1982-11-15 1985-07-02 Pfizer Inc. Epimeric azahomoerythromycin A derivative, intermediates and method of use
US4526888A (en) 1983-04-29 1985-07-02 Bristol-Myers Company Nephrotoxicity inhibitors for aminoglycoside antibiotics
US4492688A (en) 1983-11-25 1985-01-08 Pfizer Inc. Antibacterial cyclic ethers of 9-deoxo-9a-aza-9a-homoerythromycin A and intermediates therefor
US4464527A (en) 1983-06-30 1984-08-07 Pfizer Inc. Antibacterial 9-deoxo-9a-alkyl-9a-aza-9a-homoerythromycin A derivatives and intermediates therefore
US4465674A (en) 1983-09-06 1984-08-14 Pfizer Inc. Azahomoerythromycin D derivative and intermediates therefor
JPS60214796A (ja) 1984-04-06 1985-10-28 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシン類の製法
US4518590A (en) 1984-04-13 1985-05-21 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method
JPS6281399A (ja) 1985-10-04 1987-04-14 Taisho Pharmaceut Co Ltd エリスロマイシン類のオキシム誘導体の製造法
JPS6287599A (ja) 1985-10-14 1987-04-22 Taisho Pharmaceut Co Ltd エリスロマイシン類のオキシム誘導体の製造法
US5110800A (en) 1986-02-18 1992-05-05 Eli Lilly And Company Derivatives of erythromycylamine
MX12213A (es) 1987-07-09 1993-05-01 Pfizer Metodo de preparacion de dihidrato de azitromicina cristalino
WO1989002271A1 (en) 1987-09-10 1989-03-23 Pfizer Azithromycin and derivatives as antiprotozoal agents
JP2751385B2 (ja) 1988-05-19 1998-05-18 大正製薬株式会社 エリスロマイシンａオキシム及びその塩の製造方法
US5141926A (en) 1990-04-18 1992-08-25 Abbott Laboratories Erythromycin derivatives
SI9011409A (en) 1990-07-18 1995-10-31 Pliva Pharm & Chem Works O-methyl azitromycin derivates, methods and intermediates for their preparation and methods for preparation of pharmaceuticals products which comprise them
CA2094060A1 (en) 1990-10-15 1992-04-16 Toshifumi Asaka 2'-position modified compound of erythromycin or its derivative
US5202434A (en) 1991-04-05 1993-04-13 Merck & Co., Inc. 8a-aza-8a-homoerythromycin lactams
US5189159A (en) 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
US5215980A (en) 1992-01-17 1993-06-01 Merck & Co., Inc. 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives thereof
US5332807A (en) 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
DK0699207T3 (da) 1993-05-19 1997-12-08 Pfizer Mellemprodukt til azithromycin
US5441939A (en) 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
US5605889A (en) 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin
US5808017A (en) 1996-04-10 1998-09-15 Abbott Laboratories Process for preparing erythromycin A oxime
US5958888A (en) 1996-07-02 1999-09-28 Merial, Inc. Water miscible macrolide solutions
US5723447A (en) 1996-07-02 1998-03-03 Rhone Merieux, Inc. Water miscible erythromycin solutions
ES2122905B1 (es) 1996-07-11 1999-11-16 Astur Pharma Sa Sintesis de 11,12-hidrogenoortoborato de 9-desoxo-9a-aza-11,12-desoxi-9a-metil-9a-homoeritromicina a. un procedimiento para la preparacion de 9-desoxo-9a-aza-9a-metil-9a-homoeritromicina a dihidrato (azitromicina dihidrato).
PT102006B (pt) 1997-05-19 2000-06-30 Hovione Sociedade Quimica S A Novo processo de preparacao de azitromicina
TW546302B (en) * 1998-05-08 2003-08-11 Biochemie Sa Improvements in macrolide production
CA2245398C (en) * 1998-08-21 2002-01-29 Apotex Inc. Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof
WO2002009640A2 (en) * 2000-08-01 2002-02-07 Shiva Prasad Singh Process for the preparation of anhydrous azithromycin
CA2419873A1 (en) * 2000-08-23 2002-02-28 Wockhardt Limited Process for preparation of anhydrous azithromycin
EP1390377B1 (en) 2001-05-22 2006-03-08 Pfizer Products Inc. New crystal form of azithromycin
US6855813B2 (en) 2002-07-19 2005-02-15 Alembic Limited Process for the preparation of azithromycin monohydrate
US7235646B2 (en) 2004-06-28 2007-06-26 Alembic Limited Process for the preparation of azithromycin monohydrate isopropanol clathrate
US7683162B2 (en) 2004-08-30 2010-03-23 Taro Pharmaceutical Industries Limited Process of preparing a crystalline azithromycin monohydrate

Also Published As

Publication number Publication date
DE60114028D1 (de) 2006-02-23
US20030139583A1 (en) 2003-07-24
ATE306491T1 (de) 2005-10-15
WO2002015842A2 (en) 2002-02-28
NO20030772D0 (no) 2003-02-18
ZA200301384B (en) 2004-04-02
EP1313749B1 (en) 2005-10-12
US7414114B2 (en) 2008-08-19
CA2419873A1 (en) 2002-02-28
EP1313749A4 (en) 2004-01-21
JP2004506664A (ja) 2004-03-04
EP1313749A2 (en) 2003-05-28
DE60114028T2 (de) 2006-07-13
NO20030772L (no) 2003-04-22
WO2002015842A3 (en) 2002-10-31
US20090018090A1 (en) 2009-01-15

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