AU2001279244A1 - The use and evaluation of a (2+2) photocycloaddition in immobilization of oligonucleotides on a three-dimensional hydrogel matrix - Google Patents
The use and evaluation of a (2+2) photocycloaddition in immobilization of oligonucleotides on a three-dimensional hydrogel matrixInfo
- Publication number
- AU2001279244A1 AU2001279244A1 AU2001279244A AU7924401A AU2001279244A1 AU 2001279244 A1 AU2001279244 A1 AU 2001279244A1 AU 2001279244 A AU2001279244 A AU 2001279244A AU 7924401 A AU7924401 A AU 7924401A AU 2001279244 A1 AU2001279244 A1 AU 2001279244A1
- Authority
- AU
- Australia
- Prior art keywords
- photocycloaddition
- immobilization
- oligonucleotides
- evaluation
- hydrogel matrix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 108091034117 Oligonucleotide Proteins 0.000 title 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 title 1
- 238000011156 evaluation Methods 0.000 title 1
- 239000000017 hydrogel Substances 0.000 title 1
- 239000011159 matrix material Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
- C40B50/18—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support using a particular method of attachment to the solid support
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Structural Engineering (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22407000P | 2000-08-09 | 2000-08-09 | |
| US60/224,070 | 2000-08-09 | ||
| US23230500P | 2000-09-12 | 2000-09-12 | |
| US60/232,305 | 2000-09-12 | ||
| PCT/US2001/024894 WO2002012566A2 (fr) | 2000-08-09 | 2001-08-09 | Utilisation et evaluation d'une photocycloaddition [2+2] dans une immobilisation d'oligonucleotides sur une matrice hydrogel tridimensionnelle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001279244A1 true AU2001279244A1 (en) | 2002-02-18 |
Family
ID=26918399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001279244A Abandoned AU2001279244A1 (en) | 2000-08-09 | 2001-08-09 | The use and evaluation of a (2+2) photocycloaddition in immobilization of oligonucleotides on a three-dimensional hydrogel matrix |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1307414A2 (fr) |
| AU (1) | AU2001279244A1 (fr) |
| WO (1) | WO2002012566A2 (fr) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6921638B2 (en) | 1999-06-25 | 2005-07-26 | Amersham Biosciences Ab | Hydrogel-based microarray signal amplification methods and devices therefor |
| US6664061B2 (en) * | 1999-06-25 | 2003-12-16 | Amersham Biosciences Ab | Use and evaluation of a [2+2] photoaddition in immobilization of oligonucleotides on a three-dimensional hydrogel matrix |
| WO2005065814A1 (fr) | 2004-01-07 | 2005-07-21 | Solexa Limited | Arrangements moleculaires modifies |
| GB0514936D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Preparation of templates for nucleic acid sequencing |
| US9012022B2 (en) | 2012-06-08 | 2015-04-21 | Illumina, Inc. | Polymer coatings |
| WO2014135221A1 (fr) | 2013-03-08 | 2014-09-12 | Illumina Cambridge Ltd | Composés de polyméthine et leur utilisation comme marqueurs fluorescents |
| EP2964624B1 (fr) | 2013-03-08 | 2017-01-04 | Illumina Cambridge Limited | Composés de rhodamine et leur utilisation comme marqueurs fluorescents |
| DK3431614T3 (da) | 2013-07-01 | 2021-12-06 | Illumina Inc | Katalysator fri overfladefunktionalisering og polymerpodning |
| CN105874385B (zh) | 2013-12-19 | 2021-08-20 | Illumina公司 | 包括纳米图案化表面的基底及其制备方法 |
| US10537889B2 (en) | 2013-12-31 | 2020-01-21 | Illumina, Inc. | Addressable flow cell using patterned electrodes |
| GB201408077D0 (en) | 2014-05-07 | 2014-06-18 | Illumina Cambridge Ltd | Polymethine compounds and their use as fluorescent labels |
| GB201508858D0 (en) | 2015-05-22 | 2015-07-01 | Illumina Cambridge Ltd | Polymethine compounds with long stokes shifts and their use as fluorescent labels |
| EP3325648B1 (fr) | 2015-07-17 | 2023-03-29 | Illumina, Inc. | Feuilles polymères pour applications de séquençage |
| GB201516987D0 (en) | 2015-09-25 | 2015-11-11 | Illumina Cambridge Ltd | Polymethine compounds and their use as fluorescent labels |
| US10385214B2 (en) | 2016-09-30 | 2019-08-20 | Illumina Cambridge Limited | Fluorescent dyes and their uses as biomarkers |
| WO2018114710A1 (fr) | 2016-12-22 | 2018-06-28 | Illumina Cambridge Limited | Composés coumarines et leurs utilisations en tant que marqueurs fluorescents |
| GB201711219D0 (en) | 2017-07-12 | 2017-08-23 | Illumina Cambridge Ltd | Short pendant arm linkers for nucleotides in sequencing applications |
| GB201716931D0 (en) | 2017-10-16 | 2017-11-29 | Illumina Cambridge Ltd | New fluorescent compounds and their use as biomarkers |
| US11293061B2 (en) | 2018-12-26 | 2022-04-05 | Illumina Cambridge Limited | Sequencing methods using nucleotides with 3′ AOM blocking group |
| NL2023327B1 (en) | 2019-03-01 | 2020-09-17 | Illumina Inc | Multiplexed fluorescent detection of analytes |
| JP7587424B2 (ja) | 2019-03-01 | 2024-11-20 | イルミナ ケンブリッジ リミテッド | 環外アミン置換クマリン化合物およびそれらの蛍光標識としての使用 |
| WO2020178231A1 (fr) | 2019-03-01 | 2020-09-10 | Illumina, Inc. | Détection fluorescente multiplexée d'analytes |
| US12110546B2 (en) | 2019-03-01 | 2024-10-08 | Illumina Cambridge Limited | Tertiary amine substituted coumarin compounds and uses as fluorescent labels |
| US11421271B2 (en) | 2019-03-28 | 2022-08-23 | Illumina Cambridge Limited | Methods and compositions for nucleic acid sequencing using photoswitchable labels |
| EP4065646A1 (fr) | 2019-11-27 | 2022-10-05 | Illumina Cambridge Limited | Compositions et colorants contenant du cyclooctatétraène |
| JP2023531009A (ja) | 2020-06-22 | 2023-07-20 | イルミナ ケンブリッジ リミテッド | ３’アセタールブロッキング基を有するヌクレオシド及びヌクレオチド |
| US11981964B2 (en) | 2020-07-28 | 2024-05-14 | Illumina Cambridge Limited | Substituted coumarin dyes and uses as fluorescent labels |
| US20220195517A1 (en) | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Long stokes shift chromenoquinoline dyes and uses in sequencing applications |
| US20220195196A1 (en) | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Alkylpyridinium coumarin dyes and uses in sequencing applications |
| US20220195516A1 (en) | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Methods, systems and compositions for nucleic acid sequencing |
| US20220195518A1 (en) | 2020-12-22 | 2022-06-23 | Illumina Cambridge Limited | Methods and compositions for nucleic acid sequencing |
| EP4334327A1 (fr) | 2021-05-05 | 2024-03-13 | Illumina Cambridge Limited | Colorants fluorescents contenant des hétérocycles fusionnés contenant du bis-bore et leurs utilisations dans le séquençage |
| US20220396832A1 (en) | 2021-05-20 | 2022-12-15 | Illumina Cambridge Limited | Compositions and methods for sequencing by synthesis |
| WO2023114896A1 (fr) | 2021-12-16 | 2023-06-22 | Illumina Cambridge Limited | Procédés de clivage dirigé par métal de polynucléotides liés à une surface |
| CN117813399A (zh) | 2021-12-20 | 2024-04-02 | 因美纳有限公司 | 用于化学裂解表面结合的多核苷酸的高碘酸盐组合物和方法 |
| CN117940577A (zh) | 2021-12-20 | 2024-04-26 | 因美纳有限公司 | 用于化学裂解表面结合的多核苷酸的高碘酸盐组合物和方法 |
| US20230304086A1 (en) | 2022-03-28 | 2023-09-28 | Illumina Cambridge Limited | Labeled avidin and methods for sequencing |
| US20230313292A1 (en) | 2022-03-29 | 2023-10-05 | Illumina Cambridge Limited | Chromenoquinoline dyes and uses in sequencing |
| CA3223037A1 (fr) | 2022-03-30 | 2023-10-05 | Oliver MILLER | Procedes de clivage chimique de polynucleotides lies a une surface |
| EP4499870A1 (fr) | 2022-03-31 | 2025-02-05 | Illumina, Inc. | Compositions et procédés pour améliorer des signaux de séquençage |
| EP4499659A1 (fr) | 2022-03-31 | 2025-02-05 | Illumina, Inc. | Nucléosides et nucléotides dotés d'un groupe de protection 3' vinyle utiles dans le séquençage par synthèse |
| WO2023232829A1 (fr) | 2022-05-31 | 2023-12-07 | Illumina, Inc | Compositions et procédés de séquençage d'acides nucléiques |
| EP4547675A1 (fr) | 2022-06-28 | 2025-05-07 | Illumina, Inc. | Colorants fluorescents contenant un hétérocycle de bore bis tétracyclique fusionné et leurs utilisations dans le séquençage |
| US20250361558A1 (en) | 2022-08-19 | 2025-11-27 | Illumina, Inc. | Third dna base pair site-specific dna detection |
| CN119213083A (zh) | 2022-09-30 | 2024-12-27 | 伊路米纳有限公司 | 用于减少测序期间的光损伤的组合物和方法 |
| WO2024123866A1 (fr) | 2022-12-09 | 2024-06-13 | Illumina, Inc. | Nucléosides et nucléotides à groupes bloquants 3´ et lieurs clivables |
| AU2023409219A1 (en) | 2022-12-22 | 2024-10-03 | Illumina, Inc. | Palladium catalyst compositions and methods for sequencing by synthesis |
| US20240229131A1 (en) | 2022-12-22 | 2024-07-11 | Illumina, Inc. | Transition-metal catalyst compositions and methods for sequencing by synthesis |
| US20240271206A1 (en) | 2022-12-27 | 2024-08-15 | Illumina, Inc. | Methods of sequencing using 3' allyl blocked nucleotides |
| CN119452044A (zh) | 2023-03-29 | 2025-02-14 | 因美纳公司 | 萘酰亚胺染料以及其在核酸测序中的用途 |
| AU2024247902A1 (en) | 2023-03-30 | 2024-12-12 | Illumina, Inc. | Compositions and methods for nucleic acid sequencing |
| US20250001542A1 (en) | 2023-06-09 | 2025-01-02 | Illumina, Inc. | Method for polishing a substrate |
| US20250075269A1 (en) | 2023-08-31 | 2025-03-06 | Illumina, Inc. | Compositions and methods for nucleic acid sequencing |
| US20250137048A1 (en) | 2023-10-26 | 2025-05-01 | Illumina, Inc. | 4,5-substituted naphthalimide dyes and uses in nucleic acid sequencing |
| US20250163505A1 (en) | 2023-11-17 | 2025-05-22 | Illumina, Inc. | Conjugated polymers or polymer dots as fluorescent labels |
| US20250197933A1 (en) | 2023-12-18 | 2025-06-19 | Illumina, Inc. | Hydrogel nanoparticles as labeling scaffold in sequencing |
| US20250215493A1 (en) | 2023-12-28 | 2025-07-03 | Illumina, Inc. | Nucleotides with enzymatically cleavable 3'-o-glycoside blocking groups for sequencing |
| WO2025144711A1 (fr) | 2023-12-29 | 2025-07-03 | Illumina, Inc. | Colorants polyméthiniques tricycliques pour le séquençage d'acides nucléiques |
| WO2025184226A1 (fr) | 2024-02-28 | 2025-09-04 | Illumina, Inc. | Nucléotides à coiffage terminal de phosphate |
| WO2025188906A1 (fr) | 2024-03-08 | 2025-09-12 | Illumina, Inc. | Nucléotides d'adénosine modifiés |
| WO2025221895A1 (fr) | 2024-04-19 | 2025-10-23 | Illumina, Inc. | Échafaudages polymères solubles dans l'eau pour marquage de colorant |
| WO2025230914A1 (fr) | 2024-04-29 | 2025-11-06 | Illumina, Inc. | Nucléotides avec lieurs auto-immolables déclenchés par des enzymes pour le séquençage par synthèse |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3919915A1 (de) * | 1989-06-19 | 1990-12-20 | Boehringer Mannheim Gmbh | Aminoalkylmaleimide und davon abgeleitete hapten- und antigenderivate sowie konjugate mit peptiden oder proteinen |
| US5582955A (en) * | 1994-06-23 | 1996-12-10 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon | Chemical functionalization of surfaces |
| EP0968223B1 (fr) * | 1997-01-08 | 2016-12-21 | Sigma-Aldrich Co. LLC | Bioconjugaison de macromolecules |
| EP1138762A1 (fr) * | 1998-12-10 | 2001-10-04 | Takara Shuzo Co, Ltd. | Procede relatif a l'immobilisation d'un oligonucleotide sur un support |
| US6372813B1 (en) * | 1999-06-25 | 2002-04-16 | Motorola | Methods and compositions for attachment of biomolecules to solid supports, hydrogels, and hydrogel arrays |
| EP1287404A4 (fr) * | 2000-05-01 | 2003-10-15 | Proligo Llc | Procede d'immobilisation d'oligonucleotides au moyen du procede de bioconjugaison de cycloaddition |
-
2001
- 2001-08-09 WO PCT/US2001/024894 patent/WO2002012566A2/fr not_active Ceased
- 2001-08-09 AU AU2001279244A patent/AU2001279244A1/en not_active Abandoned
- 2001-08-09 EP EP01957507A patent/EP1307414A2/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1307414A2 (fr) | 2003-05-07 |
| WO2002012566A2 (fr) | 2002-02-14 |
| WO2002012566A3 (fr) | 2003-01-09 |
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