|
US8933236B2
(en)
|
2012-05-22 |
2015-01-13 |
Xenon Pharmaceuticals Inc. |
N-substituted benzamides and methods of use thereof
|
|
US20050020945A1
(en)
*
|
2002-07-02 |
2005-01-27 |
Tosaya Carol A. |
Acoustically-aided cerebrospinal-fluid manipulation for neurodegenerative disease therapy
|
|
US20040049134A1
(en)
*
|
2002-07-02 |
2004-03-11 |
Tosaya Carol A. |
System and methods for treatment of alzheimer's and other deposition-related disorders of the brain
|
|
US8353853B1
(en)
*
|
2003-01-24 |
2013-01-15 |
Boston Scientific Scimed, Inc. |
Encephalic insonication
|
|
US7485706B2
(en)
*
|
2003-07-30 |
2009-02-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
Neurodegenerative protein aggregation inhibition methods and compounds
|
|
US20050074506A1
(en)
*
|
2003-10-02 |
2005-04-07 |
Brainsgate Ltd. |
Targeted release of nitric oxide in the CNS circulation for modulating the BBB and treating disorders
|
|
US7896821B1
(en)
*
|
2003-11-14 |
2011-03-01 |
Perfusion Technology, LLC |
Low intensity directed ultrasound (LODUS) mediated blood brain barrier disruption
|
|
US7641660B2
(en)
*
|
2004-03-08 |
2010-01-05 |
Biomet Manufacturing Corporation |
Method, apparatus, and system for image guided bone cutting
|
|
WO2006044996A2
(en)
*
|
2004-10-15 |
2006-04-27 |
The Trustees Of Columbia University In The City Of New York |
System and method for automated boundary detection of body structures
|
|
WO2006044997A2
(en)
*
|
2004-10-15 |
2006-04-27 |
The Trustees Of Columbia University In The City Of New York |
System and method for localized measurement and imaging of viscosity of tissues
|
|
WO2006096755A2
(en)
*
|
2005-03-07 |
2006-09-14 |
The Brigham And Women's Hospital, Inc. |
Adaptive ultrasound delivery system
|
|
US10687785B2
(en)
|
2005-05-12 |
2020-06-23 |
The Trustees Of Columbia Univeristy In The City Of New York |
System and method for electromechanical activation of arrhythmias
|
|
US8858441B2
(en)
*
|
2005-05-12 |
2014-10-14 |
The Trustees Of Columbia University In The City Of New York |
System and method for electromechanical wave imaging of body structures
|
|
US20070016040A1
(en)
*
|
2005-06-24 |
2007-01-18 |
Henry Nita |
Methods and apparatus for intracranial ultrasound delivery
|
|
EP1937151A4
(en)
*
|
2005-09-19 |
2011-07-06 |
Univ Columbia |
SYSTEMS AND METHOD FOR OPENING THE BLOOD-BRAIN BARRIER OF A PERSON WITH ULTRASOUND
|
|
US20090221916A1
(en)
*
|
2005-12-09 |
2009-09-03 |
The Trustees Of Columbia University In The City Of New York |
Systems and Methods for Elastography Imaging
|
|
ES2535856T3
(en)
|
2005-12-15 |
2015-05-18 |
Genentech, Inc. |
Methods and compositions for targeting polyubiquitin
|
|
US20100150928A1
(en)
|
2006-05-04 |
2010-06-17 |
Geneetech, Inc. |
Methods and compositions relating to zpa polypeptides
|
|
MY153248A
(en)
|
2006-07-14 |
2015-01-29 |
Ac Immune Sa |
Humanized antibody against amyloid beta
|
|
PL2468770T3
(en)
|
2006-07-14 |
2018-07-31 |
Ac Immune S.A. |
Humanized antibody against amyloid beta.
|
|
WO2008027520A2
(en)
*
|
2006-08-30 |
2008-03-06 |
The Trustees Of Columbia University In The City Of New York |
Systems and methods for composite elastography and wave imaging
|
|
US7960139B2
(en)
|
2007-03-23 |
2011-06-14 |
Academia Sinica |
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
|
|
BRPI0812484A2
(en)
|
2007-06-12 |
2018-06-05 |
Ac Immune Sa |
monoclonal antibody, light chain and heavy chain variable regions, isolated cdr, polynucleotide, therapeutic composition, methods for treating disease and disorder, for producing an antibody, for treating or alleviating the effects of disease and disorder, for reducing plaque burden in an individual's brain, to reduce the amount of plaque in an individual's brain, to decrease the total amount of soluble spruce in an individual's brain, to retain or increase an individual's cognitive memory capacity, to diagnose from or to diagnose a predisposition to an amyloid-associated disease or condition in a patient, to determine the extent of amyloidogenic plaque burden in an individual's tissue, to monitor minimal residual disease in an individual, and to predict an individual's responsiveness, cell line , test kit, epitope fir
|
|
TWI557136B
(en)
|
2007-06-12 |
2016-11-11 |
Ac免疫公司 |
Antibody and related nucleic acid molecules, expression vectors, cells, compositions, kits, methods and uses for specifically binding β-amyloid proteins
|
|
AU2008311366B2
(en)
|
2007-10-05 |
2015-03-12 |
Ac Immune S.A. |
Use of anti-amyloid beta antibody in ocular diseases
|
|
JP2011501662A
(en)
*
|
2007-10-12 |
2011-01-13 |
ザ・プロウボウスト・フェロウズ・アンド・スカラーズ・オブ・ザ・カレッジ・オブ・ザ・ホリー・アンド・アンデバイデッド・トリニティ・オブ・クイーン・エリザベス・ニア・ダブリン |
Method for releasing tight bonds
|
|
TWI580694B
(en)
|
2007-11-30 |
2017-05-01 |
建南德克公司 |
Anti-vegf antibodies
|
|
EP2318832B1
(en)
|
2008-07-15 |
2013-10-09 |
Academia Sinica |
Glycan arrays on ptfe-like aluminum coated glass slides and related methods
|
|
WO2010014977A1
(en)
*
|
2008-08-01 |
2010-02-04 |
The Trustees Of Columbia University In The City Of New York |
Systems and methods for matching and imaging tissue characteristics
|
|
WO2010030819A1
(en)
*
|
2008-09-10 |
2010-03-18 |
The Trustees Of Columbia University In The City Of New York |
Systems and methods for opening a tissue
|
|
EP3524620A1
(en)
|
2008-10-14 |
2019-08-14 |
Genentech, Inc. |
Immunoglobulin variants and uses thereof
|
|
CA2741089A1
(en)
|
2008-10-22 |
2010-04-29 |
Genentech, Inc. |
Modulation of axon degeneration
|
|
KR20170143025A
(en)
|
2008-12-23 |
2017-12-28 |
제넨테크, 인크. |
Immunoglobulin variants with altered binding to protein a
|
|
US9321823B2
(en)
|
2009-09-02 |
2016-04-26 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
|
EP2480144B1
(en)
|
2009-09-21 |
2024-03-06 |
The Trustees of Columbia University in the City of New York |
Systems for opening of a tissue barrier
|
|
US8986231B2
(en)
|
2009-10-12 |
2015-03-24 |
Kona Medical, Inc. |
Energetic modulation of nerves
|
|
US20110092880A1
(en)
*
|
2009-10-12 |
2011-04-21 |
Michael Gertner |
Energetic modulation of nerves
|
|
US8469904B2
(en)
|
2009-10-12 |
2013-06-25 |
Kona Medical, Inc. |
Energetic modulation of nerves
|
|
US11998266B2
(en)
|
2009-10-12 |
2024-06-04 |
Otsuka Medical Devices Co., Ltd |
Intravascular energy delivery
|
|
US9119951B2
(en)
|
2009-10-12 |
2015-09-01 |
Kona Medical, Inc. |
Energetic modulation of nerves
|
|
US9174065B2
(en)
|
2009-10-12 |
2015-11-03 |
Kona Medical, Inc. |
Energetic modulation of nerves
|
|
US20160059044A1
(en)
|
2009-10-12 |
2016-03-03 |
Kona Medical, Inc. |
Energy delivery to intraparenchymal regions of the kidney to treat hypertension
|
|
US20110118600A1
(en)
*
|
2009-11-16 |
2011-05-19 |
Michael Gertner |
External Autonomic Modulation
|
|
US8986211B2
(en)
|
2009-10-12 |
2015-03-24 |
Kona Medical, Inc. |
Energetic modulation of nerves
|
|
US8295912B2
(en)
|
2009-10-12 |
2012-10-23 |
Kona Medical, Inc. |
Method and system to inhibit a function of a nerve traveling with an artery
|
|
US8517962B2
(en)
|
2009-10-12 |
2013-08-27 |
Kona Medical, Inc. |
Energetic modulation of nerves
|
|
JP2013508401A
(en)
|
2009-10-22 |
2013-03-07 |
ジェネンテック, インコーポレイテッド |
Regulation of axonal degeneration
|
|
US10087236B2
(en)
|
2009-12-02 |
2018-10-02 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
|
US11377485B2
(en)
|
2009-12-02 |
2022-07-05 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
|
WO2011071577A1
(en)
|
2009-12-11 |
2011-06-16 |
Genentech, Inc. |
Anti-vegf-c antibodies and methods using same
|
|
RU2559542C2
(en)
|
2009-12-23 |
2015-08-10 |
Дженентек, Инк. |
Anti-bv8 antibodies and using them
|
|
WO2011130332A1
(en)
|
2010-04-12 |
2011-10-20 |
Academia Sinica |
Glycan arrays for high throughput screening of viruses
|
|
DK2568976T3
(en)
|
2010-05-10 |
2016-01-11 |
Academia Sinica |
Zanamivir-phosphonate congener with the anti-influenza activity, and determining the sensitivity oseltamivir in influenza viruses
|
|
AU2011282536B2
(en)
|
2010-07-30 |
2015-12-24 |
Ac Immune S.A. |
Safe and functional humanized anti beta-amyloid antibody
|
|
EP2603233A1
(en)
|
2010-08-12 |
2013-06-19 |
AC Immune S.A. |
Vaccine engineering
|
|
US8481680B2
(en)
|
2010-10-05 |
2013-07-09 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
|
WO2012045882A2
(en)
|
2010-10-07 |
2012-04-12 |
Ac Immune S.A. |
Pharmaceutical composition
|
|
TW201223561A
(en)
|
2010-10-26 |
2012-06-16 |
Ac Immune Sa |
Preparation of an antigenic construct
|
|
WO2012064836A1
(en)
|
2010-11-10 |
2012-05-18 |
Genentech, Inc. |
Methods and compositions for neural disease immunotherapy
|
|
US9320491B2
(en)
|
2011-04-18 |
2016-04-26 |
The Trustees Of Columbia University In The City Of New York |
Ultrasound devices methods and systems
|
|
WO2012162664A1
(en)
|
2011-05-26 |
2012-11-29 |
The Trustees Of Columbia University In The City Of New York |
Systems and methods for opening of a tissue barrier in primates
|
|
MX354662B
(en)
|
2011-10-07 |
2018-03-14 |
Ac Immune Sa |
Phosphospecific antibodies recognising tau.
|
|
EP2766028B1
(en)
|
2011-10-14 |
2017-08-16 |
F. Hoffmann-La Roche AG |
Peptide inhibitors of bace1
|
|
JP6338530B2
(en)
|
2011-11-10 |
2018-06-06 |
ジェネンテック, インコーポレイテッド |
Methods for treating, diagnosing, and monitoring Alzheimer's disease
|
|
KR102132041B1
(en)
|
2012-04-05 |
2020-07-09 |
에이씨 이뮨 에스.에이. |
Humanized Tau Antibody
|
|
US10130714B2
(en)
|
2012-04-14 |
2018-11-20 |
Academia Sinica |
Enhanced anti-influenza agents conjugated with anti-inflammatory activity
|
|
MX2014013407A
(en)
|
2012-05-22 |
2014-11-26 |
Hoffmann La Roche |
Substituted dipyridylamines and uses thereof.
|
|
BR112015000187A2
(en)
|
2012-07-06 |
2017-06-27 |
Genentech Inc |
benzamides substituted with n and methods of use thereof
|
|
EP2885311B1
(en)
|
2012-08-18 |
2020-01-01 |
Academia Sinica |
Cell-permeable probes for identification and imaging of sialidases
|
|
US9547009B2
(en)
|
2012-08-21 |
2017-01-17 |
Academia Sinica |
Benzocyclooctyne compounds and uses thereof
|
|
GB2505740A
(en)
*
|
2012-09-05 |
2014-03-12 |
Surf Technology As |
Instrument and method for ultrasound mediated drug delivery
|
|
KR20150061647A
(en)
|
2012-09-27 |
2015-06-04 |
에프. 호프만-라 로슈 아게 |
Substituted sulfonamide compounds
|
|
WO2014059170A1
(en)
|
2012-10-10 |
2014-04-17 |
The Trustees Of Columbia University In The City Of New York |
Systems and methods for mechanical mapping of cardiac rhythm
|
|
AU2013204200B2
(en)
|
2012-10-11 |
2016-10-20 |
Brandeis University |
Treatment of amyotrophic lateral sclerosis
|
|
DE102012222778A1
(en)
*
|
2012-12-11 |
2014-06-12 |
Siemens Aktiengesellschaft |
Intravascular ultrasound source for reversible overcoming of blood-brain barrier in e.g. human, has catheter to move source through blood vessel to place within skull of human or animal, so as to locally overcome blood-brain barrier
|
|
BR112015016395A2
(en)
|
2013-01-18 |
2017-07-11 |
Hoffmann La Roche |
3-substituted pyrazoles and use as dlk inhibitors
|
|
KR20150131233A
(en)
|
2013-03-14 |
2015-11-24 |
제넨테크, 인크. |
Substituted triazolopyridines and methods of use thereof
|
|
EP2970452A2
(en)
|
2013-03-15 |
2016-01-20 |
AC Immune S.A. |
Anti-tau antibodies and methods of use
|
|
MA42164B1
(en)
|
2013-05-01 |
2019-12-31 |
Hoffmann La Roche |
Biheteroaryl compounds and their uses
|
|
KR20160002850A
(en)
|
2013-05-01 |
2016-01-08 |
에프. 호프만-라 로슈 아게 |
C-linked heterocycloalkyl substituted pyrimidines and their uses
|
|
US9247921B2
(en)
|
2013-06-07 |
2016-02-02 |
The Trustees Of Columbia University In The City Of New York |
Systems and methods of high frame rate streaming for treatment monitoring
|
|
US10086054B2
(en)
|
2013-06-26 |
2018-10-02 |
Academia Sinica |
RM2 antigens and use thereof
|
|
US9981030B2
(en)
|
2013-06-27 |
2018-05-29 |
Academia Sinica |
Glycan conjugates and use thereof
|
|
US10322178B2
(en)
|
2013-08-09 |
2019-06-18 |
The Trustees Of Columbia University In The City Of New York |
Systems and methods for targeted drug delivery
|
|
US10028723B2
(en)
|
2013-09-03 |
2018-07-24 |
The Trustees Of Columbia University In The City Of New York |
Systems and methods for real-time, transcranial monitoring of blood-brain barrier opening
|
|
WO2015035337A1
(en)
|
2013-09-06 |
2015-03-12 |
Academia Sinica |
HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS
|
|
KR20160055861A
(en)
|
2013-09-17 |
2016-05-18 |
오비아이 파머 인코퍼레이티드 |
Compositions of a carbohydrate vaccine for inducing immune responses and uses thereof in cancer treatment
|
|
LT3055302T
(en)
|
2013-10-11 |
2019-03-12 |
F. Hoffmann-La Roche Ag |
Substituted heterocyclic sulfonamide compounds useful as trpa1 modulators
|
|
MX2016008110A
(en)
|
2013-12-20 |
2016-08-19 |
Hoffmann La Roche |
Pyrazole derivatives and uses thereof as inhibitors of dlk.
|
|
US9982041B2
(en)
|
2014-01-16 |
2018-05-29 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
|
WO2016114819A1
(en)
|
2015-01-16 |
2016-07-21 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
|
US10150818B2
(en)
|
2014-01-16 |
2018-12-11 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
|
DK3102197T3
(en)
|
2014-02-04 |
2018-11-19 |
Genentech Inc |
Smoothened mutant and methods for its use
|
|
EP3129767B1
(en)
|
2014-03-27 |
2021-09-01 |
Academia Sinica |
Reactive labelling compounds and uses thereof
|
|
US10478120B2
(en)
|
2014-05-17 |
2019-11-19 |
The Johns Hopkins University |
MRI-guided intraarterial catheter-based method for predicting territory of local blood brain barrier opening
|
|
CN106573971A
(en)
|
2014-05-27 |
2017-04-19 |
中央研究院 |
anti-CD 20 glycoantibodies and uses thereof
|
|
US10118969B2
(en)
|
2014-05-27 |
2018-11-06 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
|
CA2950440A1
(en)
|
2014-05-27 |
2015-12-03 |
Academia Sinica |
Anti-her2 glycoantibodies and uses thereof
|
|
AU2015267051B2
(en)
|
2014-05-27 |
2022-03-17 |
Academia Sinica |
Fucosidase from bacteroides and methods using the same
|
|
CN106714829A
(en)
|
2014-05-28 |
2017-05-24 |
中央研究院 |
anti-TNF-alpha carbohydrate antibodies and uses thereof
|
|
AU2015278254A1
(en)
|
2014-06-20 |
2016-12-22 |
The University Of Queensland |
Neurodegenerative disease treatment
|
|
WO2016007534A1
(en)
|
2014-07-07 |
2016-01-14 |
Genentech, Inc. |
Therapeutic compounds and methods of use thereof
|
|
US9879042B2
(en)
|
2014-09-08 |
2018-01-30 |
Academia Sinica |
Human iNKT cell activation using glycolipids
|
|
US10925579B2
(en)
|
2014-11-05 |
2021-02-23 |
Otsuka Medical Devices Co., Ltd. |
Systems and methods for real-time tracking of a target tissue using imaging before and during therapy delivery
|
|
CN107108745B
(en)
|
2014-11-19 |
2021-01-12 |
基因泰克公司 |
Antibodies against BACE1 and their use for immunotherapy of neurological diseases
|
|
RS61431B1
(en)
|
2014-11-19 |
2021-03-31 |
Axon Neuroscience Se |
Humanized tau antibodies in alzheimer's disease
|
|
US20190030374A1
(en)
|
2014-12-19 |
2019-01-31 |
Universite Pierre Et Marie Curie (Paris 6) |
Implantable ultrasound generating treating device for brain treatment, apparatus comprising such device and method implementing such device
|
|
US9975965B2
(en)
|
2015-01-16 |
2018-05-22 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
|
US10495645B2
(en)
|
2015-01-16 |
2019-12-03 |
Academia Sinica |
Cancer markers and methods of use thereof
|
|
CA2972731A1
(en)
|
2015-01-24 |
2016-07-28 |
Chi-Huey Wong |
Cancer markers and methods of use thereof
|
|
AU2015378564A1
(en)
|
2015-01-24 |
2017-07-13 |
Academia Sinica |
Novel glycan conjugates and methods of use thereof
|
|
EP3250590B1
(en)
|
2015-01-30 |
2021-09-15 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced anti-ssea4 antibody efficacy
|
|
CA2975875A1
(en)
|
2015-02-04 |
2016-08-11 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
|
JP6701225B2
(en)
|
2015-03-09 |
2020-05-27 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
Tricyclic DLK inhibitors and uses thereof
|
|
EP3297989A1
(en)
|
2015-05-22 |
2018-03-28 |
Genentech, Inc. |
Substituted benzamides and methods of use thereof
|
|
CN108137477A
(en)
|
2015-08-27 |
2018-06-08 |
基因泰克公司 |
Therapeutic compounds and its application method
|
|
KR20180050339A
(en)
|
2015-09-04 |
2018-05-14 |
오비아이 파머 인코퍼레이티드 |
Glycan arrays and how to use them
|
|
EP3380466A1
(en)
|
2015-11-25 |
2018-10-03 |
Genentech, Inc. |
Substituted benzamides useful as sodium channel blockers
|
|
JP2019509721A
(en)
|
2016-02-04 |
2019-04-11 |
キュリス,インコーポレイテッド |
Mutant smoothened and method of using the same
|
|
KR20180114210A
(en)
|
2016-03-08 |
2018-10-17 |
아카데미아 시니카 |
Method for synthesizing N-glycan and its array
|
|
EP3426157B1
(en)
|
2016-03-11 |
2022-02-16 |
Sorbonne Universite |
External ultrasound generating treating device for spinal cord and spinal nerves treatment
|
|
CA3016001C
(en)
|
2016-03-11 |
2023-08-15 |
Sorbonne Universite |
Implantable ultrasound generating treating device for spinal cord and/or spinal nerve treatment, apparatus comprising such device and method
|
|
US11041017B2
(en)
|
2016-03-29 |
2021-06-22 |
Obi Pharma, Inc. |
Antibodies, pharmaceutical compositions and methods
|
|
US10980894B2
(en)
|
2016-03-29 |
2021-04-20 |
Obi Pharma, Inc. |
Antibodies, pharmaceutical compositions and methods
|
|
US10766858B2
(en)
|
2016-03-30 |
2020-09-08 |
Genentech, Inc. |
Substituted benzamides and methods of use thereof
|
|
AU2017252128B2
(en)
|
2016-04-22 |
2024-06-06 |
Obi Pharma, Inc. |
Cancer immunotherapy by immune activation or immune modulation via Globo series antigens
|
|
WO2018015410A1
(en)
|
2016-07-20 |
2018-01-25 |
F. Hoffmann-La Roche Ag |
Bicyclic proline compounds
|
|
EP3487849A1
(en)
|
2016-07-20 |
2019-05-29 |
H. Hoffnabb-La Roche Ag |
Sulfonylcycloalkyl carboxamide compounds as trpa1 modulators
|
|
KR20230117482A
(en)
|
2016-07-27 |
2023-08-08 |
오비아이 파머 인코퍼레이티드 |
Immunogenic/therapeutic glycan compositions and uses thereof
|
|
CN110062767B
(en)
|
2016-07-29 |
2023-07-11 |
台湾浩鼎生技股份有限公司 |
Human antibodies, pharmaceutical compositions and methods
|
|
WO2018029288A1
(en)
|
2016-08-12 |
2018-02-15 |
F. Hoffmann-La Roche Ag |
Sulfonyl pyridyl trp inhibitors
|
|
US10538592B2
(en)
|
2016-08-22 |
2020-01-21 |
Cho Pharma, Inc. |
Antibodies, binding fragments, and methods of use
|
|
EP3526219B1
(en)
|
2016-10-17 |
2021-12-15 |
F. Hoffmann-La Roche AG |
Bicyclic pyridone lactams and methods of use thereof
|
|
TWI822055B
(en)
|
2016-11-21 |
2023-11-11 |
台灣浩鼎生技股份有限公司 |
Conjugated biological molecules, pharmaceutical compositions and methods
|
|
TW201831477A
(en)
|
2016-11-28 |
2018-09-01 |
瑞士商赫孚孟拉羅股份公司 |
Oxadiazolone transient receptor potential channel inhibitors
|
|
TW201831478A
(en)
|
2016-12-02 |
2018-09-01 |
瑞士商赫孚孟拉羅股份公司 |
Bicyclic guanamine compound and method of use thereof
|
|
US11072607B2
(en)
|
2016-12-16 |
2021-07-27 |
Genentech, Inc. |
Inhibitors of RIP1 kinase and methods of use thereof
|
|
JP7178357B2
(en)
|
2017-03-07 |
2022-11-25 |
エフ.ホフマン-ラ ロシュ アーゲー |
Oxadiazole transient receptor potential channel inhibitor
|
|
EP3601273B1
(en)
|
2017-03-24 |
2021-12-01 |
Genentech, Inc. |
4-piperidin-n-(pyrimidin-4-yl)chroman-7-sulfonamide derivatives as sodium channel inhibitors
|
|
KR102664604B1
(en)
|
2017-07-14 |
2024-05-14 |
에프. 호프만-라 로슈 아게 |
Bicyclic ketone compounds and methods of using them
|
|
US20200368352A1
(en)
*
|
2017-08-15 |
2020-11-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
Polymeric perfluorocarbon nanoemulsions for ultrasonic drug uncaging
|
|
EP3460057A1
(en)
|
2017-09-22 |
2019-03-27 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Kdac variants and uses thereof
|
|
EP3694858B1
(en)
|
2017-10-11 |
2023-01-11 |
F. Hoffmann-La Roche AG |
Bicyclic compounds for use as rip1 kinase inhibitors
|
|
AU2018360270A1
(en)
|
2017-10-31 |
2020-03-26 |
F. Hoffmann-La Roche Ag |
Bicyclic sulfones and sulfoxides and methods of use thereof
|
|
EP4295916A3
(en)
|
2017-11-30 |
2024-03-20 |
Hanmi Pharm. Co., Ltd. |
Salts of 4-amino-n-(1-((3-chloro-2-fluorophenyl)amino)-6-methylisoquinolin-5-yl)thieno[3,2-d]pyrimidine-7-carboxamide, and crystalline forms thereof
|
|
WO2019164778A1
(en)
|
2018-02-20 |
2019-08-29 |
Genentech, Inc. |
Process for preparing 1-arylsulfonyl-pyrrolidine-2-carboxamide transient receptor potential channel antagonist compounds and crystalline forms thereof
|
|
CN112041313A
(en)
|
2018-02-26 |
2020-12-04 |
基因泰克公司 |
Pyridine-sulfonamide compounds and their use against pain and related conditions
|
|
US10710994B2
(en)
|
2018-03-19 |
2020-07-14 |
Genentech, Inc. |
Oxadiazole transient receptor potential channel inhibitors
|
|
WO2019186276A2
(en)
|
2018-03-28 |
2019-10-03 |
Axon Neuroscience Se |
Antibody-based methods of detecting and treating alzheimer's disease
|
|
JP2021519788A
(en)
|
2018-03-30 |
2021-08-12 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
Condensation ring hydropyrido compound as a sodium channel inhibitor
|
|
JP7398391B2
(en)
|
2018-04-20 |
2023-12-14 |
エフ. ホフマン-ラ ロシュ アーゲー |
N-[4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxamide derivative and Related compounds as RIP1 kinase inhibitors, for example to treat irritable bowel syndrome (IBS)
|
|
TW202003490A
(en)
|
2018-05-22 |
2020-01-16 |
瑞士商赫孚孟拉羅股份公司 |
Therapeutic compounds and methods of use thereof
|
|
WO2020006176A1
(en)
|
2018-06-27 |
2020-01-02 |
Obi Pharma, Inc. |
Glycosynthase variants for glycoprotein engineering and methods of use
|
|
TW202024023A
(en)
|
2018-09-03 |
2020-07-01 |
瑞士商赫孚孟拉羅股份公司 |
Therapeutic compounds and methods of use
|
|
CA3217998A1
(en)
*
|
2018-10-04 |
2020-04-09 |
Synaptec Network, Inc. |
Systems and methods for delivering exosomes through the blood-brain barrier
|
|
US11554267B2
(en)
|
2018-10-05 |
2023-01-17 |
Synaptec Network, Inc. |
Systems and methods for delivering therapeutic agents to the brain using TMS
|
|
WO2020077380A1
(en)
*
|
2018-10-17 |
2020-04-23 |
The University Of Queensland |
Methods and compositions for treating tauopathies
|
|
FR3089128B1
(en)
|
2018-11-30 |
2020-12-18 |
Carthera |
ACOUSTIC WINDOW FOR IMAGING AND / OR TREATMENT OF CEREBRAL TISSUE
|
|
CN113302193A
(en)
|
2019-01-11 |
2021-08-24 |
豪夫迈·罗氏有限公司 |
Bicyclic pyrrolotriazolone compounds and methods of use thereof
|
|
CA3128067C
(en)
*
|
2019-02-13 |
2025-11-25 |
Alpheus Medical, Inc. |
Non-invasive sonodynamic therapy
|
|
WO2021097110A1
(en)
|
2019-11-13 |
2021-05-20 |
Genentech, Inc. |
Therapeutic compounds and methods of use
|
|
AU2020394842A1
(en)
|
2019-12-04 |
2022-06-30 |
Ac Immune Sa |
Novel molecules for therapy and diagnosis
|
|
US11787775B2
(en)
|
2020-07-24 |
2023-10-17 |
Genentech, Inc. |
Therapeutic compounds and methods of use
|
|
CN116209470A
(en)
|
2020-08-07 |
2023-06-02 |
阿尔菲斯医疗股份有限公司 |
Ultrasound array for enhanced sonodynamic therapy for cancer treatment
|
|
EP4196162A1
(en)
|
2020-08-14 |
2023-06-21 |
AC Immune SA |
Humanized anti-tdp-43 binding molecules and uses thereof
|
|
BR112023005853A2
(en)
|
2020-10-02 |
2023-05-02 |
Genentech Inc |
PROCESS FOR PREPARING A COMPOUND OF FORMULA I, COMPOUNDS, PROCESSES FOR PREPARING COMPOUND 1, CRYSTALLINE FORM, PHARMACEUTICAL COMPOSITION, PROCESS FOR PREPARING THE CRYSTALLINE FORM OF COMPOUND I AND METHOD FOR TREATMENT OF A NEURODEGENERATIVE CONDITION
|
|
EP4229082A1
(en)
|
2020-10-16 |
2023-08-23 |
AC Immune SA |
Antibodies binding to alpha-synuclein for therapy and diagnosis
|
|
EP4351716A1
(en)
*
|
2021-06-17 |
2024-04-17 |
Aselsan Elektronik Sanayi ve Ticaret Anonim Sirketi |
An arrangement for vaporizing nanoagents suitable for therapy inside the human body and a device comprising this arrangement
|
|
WO2023028056A1
(en)
|
2021-08-24 |
2023-03-02 |
Genentech, Inc. |
3-amino piperidyl sodium channel inhibitors
|
|
WO2023028077A1
(en)
|
2021-08-24 |
2023-03-02 |
Genentech, Inc. |
Sodium channel inhibitors and methods of designing same
|
|
JP2024541508A
(en)
|
2021-11-24 |
2024-11-08 |
ジェネンテック, インコーポレイテッド |
Therapeutic indazole compounds and methods of use in the treatment of cancer - Patents.com
|
|
US12275745B2
(en)
|
2021-11-24 |
2025-04-15 |
Genentech, Inc. |
Therapeutic compounds and methods of use
|
|
EP4479426A1
(en)
|
2022-02-16 |
2024-12-25 |
AC Immune SA |
Humanized anti-tdp-43 binding molecules and uses thereof
|
|
JP2025513799A
(en)
|
2022-04-08 |
2025-04-30 |
エイシー イミューン ソシエテ アノニム |
Anti-TDP-43 binding molecule
|
|
KR20250102135A
(en)
|
2022-10-11 |
2025-07-04 |
메이라지티엑스 유케이 Ii 리미티드 |
UPF1 expression construct
|
|
US20240142472A1
(en)
|
2022-10-24 |
2024-05-02 |
West Virginia University Board of Governors on behalf of West Virginia University |
Methods of improving neurodegenerative disorders by targeted delivery of therapeutic agents
|
|
WO2024184494A1
(en)
|
2023-03-08 |
2024-09-12 |
Ac Immune Sa |
Anti-tdp-43 binding molecules and uses thereof
|