AU2001278517A1 - Nucleic acid binding compounds containing pyrazolo(3,4-d)pyrimidine analogues of purin-2,6-diamine and their uses - Google Patents
Nucleic acid binding compounds containing pyrazolo(3,4-d)pyrimidine analogues of purin-2,6-diamine and their usesInfo
- Publication number
- AU2001278517A1 AU2001278517A1 AU2001278517A AU7851701A AU2001278517A1 AU 2001278517 A1 AU2001278517 A1 AU 2001278517A1 AU 2001278517 A AU2001278517 A AU 2001278517A AU 7851701 A AU7851701 A AU 7851701A AU 2001278517 A1 AU2001278517 A1 AU 2001278517A1
- Authority
- AU
- Australia
- Prior art keywords
- nucleic acid
- acid binding
- purin
- diamine
- compounds containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- QUKPALAWEPMWOS-UHFFFAOYSA-N 1h-pyrazolo[3,4-d]pyrimidine Chemical class C1=NC=C2C=NNC2=N1 QUKPALAWEPMWOS-UHFFFAOYSA-N 0.000 title 1
- ZTAWTRPFJHKMRU-UHFFFAOYSA-N 7-deaza-8-aza-2,6-diaminopurine Chemical class NC1=NC(N)=C2NN=CC2=N1 ZTAWTRPFJHKMRU-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The present invention is in the field of nucleic acid binding compounds comprising 7-substituted 7-deaza-8aza-2,6-diamino-purine bases, compounds useful for the preparation of such compounds, various uses thereof and methods for the determination of nucleic acids using said compounds in the field of diagnostics.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00116816 | 2000-08-03 | ||
| EP00116816 | 2000-08-03 | ||
| EP01109438 | 2001-04-24 | ||
| EP01109438 | 2001-04-24 | ||
| PCT/EP2001/008850 WO2002012263A1 (en) | 2000-08-03 | 2001-07-31 | Nucleic acid binding compounds containing pyrazolo[3,4-d]pyrimidine analogues of purin-2,6-diamine and their uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001278517A1 true AU2001278517A1 (en) | 2002-02-18 |
Family
ID=26071249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001278517A Abandoned AU2001278517A1 (en) | 2000-08-03 | 2001-07-31 | Nucleic acid binding compounds containing pyrazolo(3,4-d)pyrimidine analogues of purin-2,6-diamine and their uses |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7238795B2 (en) |
| EP (1) | EP1307469B1 (en) |
| JP (1) | JP4331476B2 (en) |
| AT (1) | ATE384731T1 (en) |
| AU (1) | AU2001278517A1 (en) |
| CA (1) | CA2416631C (en) |
| DE (1) | DE60132596T2 (en) |
| ES (1) | ES2300346T3 (en) |
| WO (1) | WO2002012263A1 (en) |
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| US9708358B2 (en) | 2000-10-06 | 2017-07-18 | The Trustees Of Columbia University In The City Of New York | Massive parallel method for decoding DNA and RNA |
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| US20080176220A1 (en) * | 2004-02-26 | 2008-07-24 | Thomsen Bioscience | Method, Kit and System for Enhanced Nested Pcr |
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| WO2006073436A2 (en) * | 2004-04-29 | 2006-07-13 | The Trustees Of Columbia University In The City Of New York | Mass tag pcr for multiplex diagnostics |
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| WO2007002204A2 (en) | 2005-06-21 | 2007-01-04 | The Trustees Of Columbia University In The City Of New York | Pyrosequencing methods and related compostions |
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| WO2007062105A2 (en) * | 2005-11-21 | 2007-05-31 | The Trustees Of Columbia University In The City Of New York | Multiplex digital immuno-sensing using a library of photocleavable mass tags |
| WO2007146158A1 (en) * | 2006-06-07 | 2007-12-21 | The Trustees Of Columbia University In The City Of New York | Dna sequencing by nanopore using modified nucleotides |
| US7772390B1 (en) | 2006-07-18 | 2010-08-10 | The Regents Of The University Of California | Lipid mediated nucleic acid synthesis |
| WO2008069973A2 (en) | 2006-12-01 | 2008-06-12 | The Trustees Of Columbia University In The City Of New York | Four-color dna sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators |
| US8535888B2 (en) | 2006-12-29 | 2013-09-17 | Mayo Foundation For Medical Education And Research | Compositions and methods for detecting methicillin-resistant S. aureus |
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| WO2009051807A1 (en) | 2007-10-19 | 2009-04-23 | The Trustees Of Columbia University In The City Of New York | Design and synthesis of cleavable fluorescent nucleotides as reversible terminators for dna sequencing by synthesis |
| EP3431615A3 (en) | 2007-10-19 | 2019-02-20 | The Trustees of Columbia University in the City of New York | Dna sequencing with non-fluorescent nucleotide reversible terminators cleavable label modified nucleotide terminators |
| BRPI0820738A2 (en) | 2007-12-14 | 2015-06-16 | Minitube America Inc | Gender-specific separation of sperm and embryo cells |
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| EP3674412A1 (en) | 2012-06-20 | 2020-07-01 | The Trustees of Columbia University in the City of New York | Nucleic acid sequencing by nanopore detection of tag molecules |
| ES2862073T3 (en) | 2012-07-13 | 2021-10-06 | Wave Life Sciences Ltd | Asymmetric auxiliary group |
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| US10648026B2 (en) | 2013-03-15 | 2020-05-12 | The Trustees Of Columbia University In The City Of New York | Raman cluster tagged molecules for biological imaging |
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-
2001
- 2001-07-31 US US10/333,518 patent/US7238795B2/en not_active Expired - Lifetime
- 2001-07-31 CA CA2416631A patent/CA2416631C/en not_active Expired - Lifetime
- 2001-07-31 AU AU2001278517A patent/AU2001278517A1/en not_active Abandoned
- 2001-07-31 EP EP01956576A patent/EP1307469B1/en not_active Expired - Lifetime
- 2001-07-31 ES ES01956576T patent/ES2300346T3/en not_active Expired - Lifetime
- 2001-07-31 JP JP2002518237A patent/JP4331476B2/en not_active Expired - Lifetime
- 2001-07-31 WO PCT/EP2001/008850 patent/WO2002012263A1/en not_active Ceased
- 2001-07-31 DE DE60132596T patent/DE60132596T2/en not_active Expired - Lifetime
- 2001-07-31 AT AT01956576T patent/ATE384731T1/en active
-
2007
- 2007-04-30 US US11/742,416 patent/US8057997B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20030198982A1 (en) | 2003-10-23 |
| EP1307469B1 (en) | 2008-01-23 |
| JP4331476B2 (en) | 2009-09-16 |
| WO2002012263A1 (en) | 2002-02-14 |
| CA2416631C (en) | 2011-11-22 |
| US8057997B2 (en) | 2011-11-15 |
| DE60132596T2 (en) | 2009-02-19 |
| US20110021365A1 (en) | 2011-01-27 |
| EP1307469A1 (en) | 2003-05-07 |
| CA2416631A1 (en) | 2002-02-14 |
| JP2004505988A (en) | 2004-02-26 |
| ES2300346T3 (en) | 2008-06-16 |
| ATE384731T1 (en) | 2008-02-15 |
| US7238795B2 (en) | 2007-07-03 |
| DE60132596D1 (en) | 2008-03-13 |
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