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AU2001278488A1 - Regulation of human matriptase-like serine protease - Google Patents

Regulation of human matriptase-like serine protease

Info

Publication number
AU2001278488A1
AU2001278488A1 AU2001278488A AU7848801A AU2001278488A1 AU 2001278488 A1 AU2001278488 A1 AU 2001278488A1 AU 2001278488 A AU2001278488 A AU 2001278488A AU 7848801 A AU7848801 A AU 7848801A AU 2001278488 A1 AU2001278488 A1 AU 2001278488A1
Authority
AU
Australia
Prior art keywords
regulation
serine protease
human matriptase
matriptase
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001278488A
Inventor
Yonghong Xiao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of AU2001278488A1 publication Critical patent/AU2001278488A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001278488A 2000-07-25 2001-07-16 Regulation of human matriptase-like serine protease Abandoned AU2001278488A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22080700P 2000-07-25 2000-07-25
US60/220,807 2000-07-25
US28010901P 2001-04-02 2001-04-02
US60/280,109 2001-04-02
PCT/EP2001/008182 WO2002008392A2 (en) 2000-07-25 2001-07-16 Regulation of human matriptase-like serine protease

Publications (1)

Publication Number Publication Date
AU2001278488A1 true AU2001278488A1 (en) 2002-02-05

Family

ID=26915210

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001278488A Abandoned AU2001278488A1 (en) 2000-07-25 2001-07-16 Regulation of human matriptase-like serine protease

Country Status (2)

Country Link
AU (1) AU2001278488A1 (en)
WO (1) WO2002008392A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040105853A1 (en) * 2000-06-12 2004-06-03 Yonghong Xiao Regulation of human epithin-like serine-protease
US7157596B2 (en) 2000-09-08 2007-01-02 Dendreon Corporation Inhibitors of serine protease activity of matriptase or MTSP1
WO2003064641A1 (en) * 2002-01-30 2003-08-07 Geneprot, Inc. Gene encoding serine proteases
AU2003269880A1 (en) * 2002-05-21 2003-12-22 Dendreon Corporation Nucleic acid molecules encoding a transmembrane serine protease 12, the encoded polypeptides and methods based thereon
US20060134719A1 (en) * 2002-07-31 2006-06-22 Masayoshi Takeda Novel serine protease
US7939304B2 (en) 2002-10-02 2011-05-10 Catalyst Biosciences, Inc. Mutant MT-SP1 proteases with altered substrate specificity or activity
US7019019B2 (en) 2002-12-23 2006-03-28 Dendreon Corporation Matriptase inhibitors and methods of use
US7439226B2 (en) 2003-09-30 2008-10-21 The United States Of America As Represented By The Department Of Health And Human Services Serine protease inhibitors
DK1735439T3 (en) 2004-04-12 2012-02-06 Catalyst Biosciences Inc Cleavage of VEGF and VEGF receptor by wild-type and mutant MT-SP1
AU2006304804B2 (en) * 2005-10-21 2011-06-02 Vertex Pharmaceuticals Incorporated Modified proteases that inhibit complement activation
EP2402437B1 (en) 2006-07-05 2016-06-01 Catalyst Biosciences, Inc. Protease screening methods and proteases identified thereby
GB0916576D0 (en) * 2009-09-22 2009-10-28 Malmsten Nils M Polypeptides and uses thereof
KR102307278B1 (en) 2014-04-29 2021-09-30 노파르티스 아게 Novel vertebrate cells and methods for recombinantly expressing a polypeptide of interest

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4072200A (en) * 1999-04-09 2000-11-14 Human Genome Sciences, Inc. 48 human secreted proteins
EP1572987A4 (en) * 2000-02-03 2005-11-30 Nuvelo Inc Novel nucleic acids and polypeptides
US6436703B1 (en) * 2000-03-31 2002-08-20 Hyseq, Inc. Nucleic acids and polypeptides
AU2001268967A1 (en) * 2000-04-18 2001-10-30 Bayer Aktiengesellschaft Regulation of human epithin-like serine protease
US20040105853A1 (en) * 2000-06-12 2004-06-03 Yonghong Xiao Regulation of human epithin-like serine-protease
EP1320614A2 (en) * 2000-06-26 2003-06-25 Sugen, Inc. Novel proteases

Also Published As

Publication number Publication date
WO2002008392A2 (en) 2002-01-31
WO2002008392A3 (en) 2002-11-21

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