AU2001278098A1 - Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms - Google Patents
Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organismsInfo
- Publication number
- AU2001278098A1 AU2001278098A1 AU2001278098A AU7809801A AU2001278098A1 AU 2001278098 A1 AU2001278098 A1 AU 2001278098A1 AU 2001278098 A AU2001278098 A AU 2001278098A AU 7809801 A AU7809801 A AU 7809801A AU 2001278098 A1 AU2001278098 A1 AU 2001278098A1
- Authority
- AU
- Australia
- Prior art keywords
- mevalonate
- genes
- manipulation
- transgenic organisms
- create novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- KJTLQQUUPVSXIM-ZCFIWIBFSA-M (R)-mevalonate Chemical compound OCC[C@](O)(C)CC([O-])=O KJTLQQUUPVSXIM-ZCFIWIBFSA-M 0.000 title 1
- KJTLQQUUPVSXIM-UHFFFAOYSA-N DL-mevalonic acid Natural products OCCC(O)(C)CC(O)=O KJTLQQUUPVSXIM-UHFFFAOYSA-N 0.000 title 1
- 230000037361 pathway Effects 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 150000003505 terpenes Chemical class 0.000 title 1
- 230000009261 transgenic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8209—Selection, visualisation of transformants, reporter constructs, e.g. antibiotic resistance markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8214—Plastid transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Nutrition Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22170300P | 2000-07-31 | 2000-07-31 | |
| US60/221,703 | 2000-07-31 | ||
| PCT/US2001/024037 WO2002010398A2 (en) | 2000-07-31 | 2001-07-31 | Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001278098A1 true AU2001278098A1 (en) | 2002-02-13 |
Family
ID=22828972
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001278098A Abandoned AU2001278098A1 (en) | 2000-07-31 | 2001-07-31 | Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms |
Country Status (4)
| Country | Link |
|---|---|
| US (8) | US20030033626A1 (en) |
| EP (3) | EP1360300A2 (en) |
| AU (1) | AU2001278098A1 (en) |
| WO (1) | WO2002010398A2 (en) |
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| US20020086380A1 (en) * | 1996-03-29 | 2002-07-04 | Francis X. Cunningham Jr | Genes encoding epsilon lycopene cyclase and method for producing bicyclic carotene |
| US6531303B1 (en) | 1998-07-06 | 2003-03-11 | Arkion Life Sciences Llc | Method of producing geranylgeraniol |
| US20120094385A1 (en) * | 2000-07-31 | 2012-04-19 | Kuehnle Agrosystems, Inc. | Gene positioning system for plastidic transformation and products thereof |
| EP1360300A2 (en) * | 2000-07-31 | 2003-11-12 | Frederick M. Hahn | Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms |
| US7192751B2 (en) | 2001-12-06 | 2007-03-20 | The Regents Of The University Of California | Biosynthesis of amorpha-4,11-diene |
| US7172886B2 (en) | 2001-12-06 | 2007-02-06 | The Regents Of The University Of California | Biosynthesis of isopentenyl pyrophosphate |
| ES2376868T3 (en) * | 2002-12-06 | 2012-03-20 | Del Monte Fresh Produce Company | Transgenic pineapple plants that have modified concentrations of carotenoids and manufacturing process |
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| JP4528297B2 (en) * | 2003-07-08 | 2010-08-18 | ディーエスエム アイピー アセッツ ビー.ブイ. | Improved production of coenzyme Q-10 |
| US7723569B2 (en) * | 2004-04-30 | 2010-05-25 | National Institute Of Agrobiological Sciences | Method for producing ubiquinone-10 in plant |
| WO2006085899A2 (en) * | 2004-05-21 | 2006-08-17 | The Regents Of The University Of California | Method for enhancing production of isoprenoid compounds |
| US8828684B2 (en) | 2004-07-27 | 2014-09-09 | The Regents Of The University Of California | Genetically modified host cells and use of same for producing isoprenoid compounds |
| EP1866428A2 (en) | 2005-03-18 | 2007-12-19 | Microbia, Inc. | Production of carotenoids in oleaginous yeast and fungi |
| BRPI0614990A2 (en) * | 2005-08-19 | 2011-04-26 | Univ California | genetically modified host cells and their use to produce isoprenoid compounds |
| JP2009511020A (en) * | 2005-10-07 | 2009-03-19 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | Nucleic acids encoding modified cytochrome P450 enzymes and methods of use thereof |
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| US9506075B2 (en) * | 2007-08-01 | 2016-11-29 | Bioglow, Llc | Bioluminescent plants comprising bacterial LUX operon and methods of making same |
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| CN102656265A (en) | 2009-04-23 | 2012-09-05 | 丹尼斯科美国公司 | Three-dimensional structure of isoprene synthase and its use thereof for generating variants |
| TW201412988A (en) * | 2009-06-17 | 2014-04-01 | Danisco Us Inc | Improved isoprene production using the dxp and mva pathway |
| EP2292741A1 (en) * | 2009-08-26 | 2011-03-09 | OrganoBalance GmbH | Genetically modified organisms for the production of lipids |
| WO2011050271A1 (en) * | 2009-10-23 | 2011-04-28 | Monsanto Technology Llc | Methods and compositions for expression of transgenes in plants |
| EP2575432B1 (en) | 2010-06-02 | 2019-08-14 | Evolva, Inc. | Recombinant production of steviol glycosides |
| JP2014502148A (en) | 2010-10-27 | 2014-01-30 | ダニスコ・ユーエス・インク | Isoprene synthase mutants aimed at improving isoprene production |
| BR112013018316A2 (en) | 2010-12-22 | 2018-09-11 | Danisco Us Inc | compositions and methods for improved isoprene production using two types of ispg enzymes |
| WO2012088450A1 (en) | 2010-12-22 | 2012-06-28 | Danisco Us Inc. | Biological production of pentose sugars using recombinant cells |
| WO2012156976A1 (en) | 2011-05-16 | 2012-11-22 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Methods of producing artemisinin in non-host plants and vectors for use in same |
| CN103732753B (en) | 2011-08-08 | 2018-03-30 | 埃沃尔瓦公司 | Recombinant Production of Steviol Glycosides |
| DK2764084T4 (en) | 2011-10-07 | 2021-12-06 | Danisco Us Inc | USE OF PHOSPHOKETOLASE IN THE MANUFACTURE OF MEVALONATE, ISOPRENOID INITIATIVES, AND ISOPRENE |
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| US20140182011A1 (en) | 2011-11-03 | 2014-06-26 | The University Of Hong Kong | Methods Using Acyl-Coenzyme A-Binding Proteins to Enchance Drought Tolerance in Genetically Modified Plants |
| US9163263B2 (en) | 2012-05-02 | 2015-10-20 | The Goodyear Tire & Rubber Company | Identification of isoprene synthase variants with improved properties for the production of isoprene |
| JP5827601B2 (en) * | 2012-07-04 | 2015-12-02 | 住友ゴム工業株式会社 | Method for adjusting expression of specific protein by light-responsive transcription factor, isoprenoid-producing plant introduced with gene encoding light-responsive transcription factor, and method for producing polyisoprenoid using the isoprenoid-producing plant |
| JP6379112B2 (en) | 2013-02-06 | 2018-08-22 | エヴォルヴァ エスアー.Evolva Sa. | Improved production method of rebaudioside D and rebaudioside M |
| MY184253A (en) | 2013-02-11 | 2021-03-29 | Evolva Sa | Efficient production of steviol glycosides in recombinant hosts |
| US9523097B2 (en) * | 2013-03-15 | 2016-12-20 | The United States Of America, As Represented By The Secretary Of Agriculture | Engineering rubber production in plants |
| US20140380524A1 (en) | 2013-06-19 | 2014-12-25 | The University Of Hong Kong | Methods of using 3-hydroxy-3-methylglutaryl-coa synthase to enhance growth and/or seed yield of genetically modified plants |
| US10421983B2 (en) | 2014-08-11 | 2019-09-24 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| US10612064B2 (en) | 2014-09-09 | 2020-04-07 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| BR112017016338A2 (en) | 2015-01-30 | 2018-03-27 | Evolva Sa | production of steviol glycosides in recombinant hosts |
| CA2979931A1 (en) | 2015-03-16 | 2016-09-22 | Dsm Ip Assets B.V. | Udp-glycosyltransferases |
| CN108271391A (en) | 2015-08-07 | 2018-07-10 | 埃沃尔瓦公司 | The generation of steviol glycoside in recombinant host |
| EP3442355A1 (en) | 2016-04-13 | 2019-02-20 | Evolva SA | Production of steviol glycosides in recombinant hosts |
| CN109312378A (en) | 2016-05-16 | 2019-02-05 | 埃沃尔瓦公司 | Production of steviol glycosides in recombinant hosts |
| JP7549444B2 (en) | 2016-06-30 | 2024-09-11 | クーンル アグロシステムズ,インコーポレイテッド | Improved heterotrophic production methods for microbial biomass and bioproducts - Patents.com |
| US11396669B2 (en) | 2016-11-07 | 2022-07-26 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| JP7198555B2 (en) | 2017-04-27 | 2023-01-04 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | Microorganisms and methods for producing cannabinoids and cannabinoid derivatives |
| US10982219B2 (en) | 2017-05-11 | 2021-04-20 | The United States Of America, As Represented By The Secretary Of Agriculture | Guayule with increased rubber production and yield |
| CN107475121A (en) * | 2017-09-19 | 2017-12-15 | 新奥科技发展有限公司 | The prevention and controls of harmful bacteria in a kind of microalga cultivation process |
| US10961541B2 (en) | 2017-09-19 | 2021-03-30 | The United States Of America As Represented By The Secretary Of Agriculture | Genetically altered guayule having increased rubber production and methods thereof |
| CN111699247A (en) | 2017-12-07 | 2020-09-22 | 齐默尔根公司 | Engineered biosynthetic pathway for the production of (6E) -8-hydroxygeraniol by fermentation |
| BR112020012704A8 (en) | 2017-12-21 | 2022-03-03 | Zymergen Inc | Nepetalactol oxidoreductases, nepetalactol synthases, and microbes capable of producing nepetalactone |
| US11377675B2 (en) | 2019-01-16 | 2022-07-05 | Kuehnle Agrosystems, Inc. | Subterranean microalgae for production of microbial biomass, substances, and compositions |
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-
2001
- 2001-07-31 EP EP01956061A patent/EP1360300A2/en not_active Withdrawn
- 2001-07-31 AU AU2001278098A patent/AU2001278098A1/en not_active Abandoned
- 2001-07-31 EP EP10185971A patent/EP2292776A1/en not_active Withdrawn
- 2001-07-31 US US09/918,740 patent/US20030033626A1/en not_active Abandoned
- 2001-07-31 WO PCT/US2001/024037 patent/WO2002010398A2/en not_active Ceased
- 2001-07-31 EP EP20100186061 patent/EP2281890A1/en not_active Withdrawn
-
2004
- 2004-04-28 US US10/835,516 patent/US7129392B2/en not_active Expired - Lifetime
-
2005
- 2005-02-08 US US11/053,541 patent/US7618819B2/en not_active Expired - Fee Related
-
2006
- 2006-07-18 US US11/489,050 patent/US20060263863A1/en not_active Abandoned
-
2008
- 2008-02-05 US US12/026,316 patent/US20080261280A1/en not_active Abandoned
-
2011
- 2011-04-22 US US13/092,608 patent/US20120083020A1/en not_active Abandoned
-
2012
- 2012-09-04 US US13/602,723 patent/US20130203132A1/en not_active Abandoned
-
2013
- 2013-11-21 US US14/086,729 patent/US8999682B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002010398A2 (en) | 2002-02-07 |
| US20130203132A1 (en) | 2013-08-08 |
| US20120083020A1 (en) | 2012-04-05 |
| EP2281890A1 (en) | 2011-02-09 |
| US20030033626A1 (en) | 2003-02-13 |
| EP1360300A2 (en) | 2003-11-12 |
| US20060263863A1 (en) | 2006-11-23 |
| EP2292776A1 (en) | 2011-03-09 |
| US20040194162A1 (en) | 2004-09-30 |
| US8999682B2 (en) | 2015-04-07 |
| US20080261280A1 (en) | 2008-10-23 |
| US20140106416A1 (en) | 2014-04-17 |
| US7618819B2 (en) | 2009-11-17 |
| US20050241017A1 (en) | 2005-10-27 |
| US7129392B2 (en) | 2006-10-31 |
| WO2002010398A3 (en) | 2003-06-26 |
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