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AU2001273499A1 - Combination of 2-methoxyestradiol and an agent that increases intracellular superoxide anion - Google Patents

Combination of 2-methoxyestradiol and an agent that increases intracellular superoxide anion

Info

Publication number
AU2001273499A1
AU2001273499A1 AU2001273499A AU7349901A AU2001273499A1 AU 2001273499 A1 AU2001273499 A1 AU 2001273499A1 AU 2001273499 A AU2001273499 A AU 2001273499A AU 7349901 A AU7349901 A AU 7349901A AU 2001273499 A1 AU2001273499 A1 AU 2001273499A1
Authority
AU
Australia
Prior art keywords
methoxyestradiol
agent
combination
superoxide anion
increases intracellular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001273499A
Inventor
Li Feng
Peng Huang
William K. Plunkett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
Original Assignee
University of Texas System
University of Texas at Austin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Texas System, University of Texas at Austin filed Critical University of Texas System
Publication of AU2001273499A1 publication Critical patent/AU2001273499A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001273499A 2000-07-12 2001-07-11 Combination of 2-methoxyestradiol and an agent that increases intracellular superoxide anion Abandoned AU2001273499A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21758900P 2000-07-12 2000-07-12
US60/217,589 2000-07-12
US09/899,807 US20020106348A1 (en) 2000-07-12 2001-07-05 Cancer therapeutics involving the administration of 2-methoxyestradiol and an agent that increases intracellular superoxide anion
US09/899,807 2001-07-05
PCT/US2001/022332 WO2002003979A2 (en) 2000-07-12 2001-07-11 Combination of 2-methoxyestradiol and an agent that increases intracellular superoxide anion

Publications (1)

Publication Number Publication Date
AU2001273499A1 true AU2001273499A1 (en) 2002-01-21

Family

ID=26912066

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001273499A Abandoned AU2001273499A1 (en) 2000-07-12 2001-07-11 Combination of 2-methoxyestradiol and an agent that increases intracellular superoxide anion

Country Status (3)

Country Link
US (1) US20020106348A1 (en)
AU (1) AU2001273499A1 (en)
WO (1) WO2002003979A2 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7062354B2 (en) 2000-11-08 2006-06-13 Orbotech Ltd. Multi-layer printed circuit board fabrication system and method
US20050019915A1 (en) 2001-06-21 2005-01-27 Bennett C. Frank Antisense modulation of superoxide dismutase 1, soluble expression
AU2002315393A1 (en) 2001-06-21 2003-01-08 Isis Pharmaceuticals, Inc. Antisense modulation of superoxide dismutase 1, soluble expression
DE60327737D1 (en) * 2002-01-22 2009-07-09 Biomatera Inc PROCESS FOR DRYING BIODEGRADABLE POLYMERS
CA2524064A1 (en) * 2003-04-29 2004-11-11 University Of Utah Research Foundation Method for detection and characterization of pre-malignant transformation
WO2005000341A1 (en) * 2003-06-25 2005-01-06 Vib Vzw Use of cytosolic phospholipid hydroperoxide glutathione peroxidase to reduce tumor growth
WO2005121316A1 (en) * 2004-06-11 2005-12-22 Bernard O'brien Institute Of Microsurgery Tissue material and muscle derived matrix
US20070148154A1 (en) * 2004-12-17 2007-06-28 Universite Rene Descartes (Paris V) Use of superoxide dismutase mimetics and reductase gultatione in the form of anticancer drugs
ES2304276B1 (en) * 2005-12-23 2009-07-28 Universidad Autonoma De Madrid Uam SYNERGIC EFFECT BETWEEN A CYANOGENIC SYSTEM AND ANOTHER OXIDATIVE INDUCTOR FOR TUMOR TREATMENT.
US8372810B2 (en) * 2007-04-11 2013-02-12 Gene Signal International Sa Anti-tumor drug, medicament, composition, and use thereof
US10485780B2 (en) * 2011-03-14 2019-11-26 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for the treatment of proliferative disorders
EP2858648B1 (en) 2012-06-07 2018-08-22 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for the inhibition of pin1
MY192634A (en) 2014-04-01 2022-08-29 Biogen Ma Inc Compositions for modulating sod-1 expression
WO2016011265A2 (en) 2014-07-17 2016-01-21 Beth Israel Deaconess Medical Center, Inc. Biomarkers for pin1-associated disorders
US9968579B2 (en) 2014-07-17 2018-05-15 Beth Isreal Deaconess Medical Center, Inc. ATRA for modulating Pin1 activity and stability
WO2016145186A1 (en) 2015-03-12 2016-09-15 Beth Israel Deaconess Medical Center, Inc. Enhanced atra-related compounds for the treatment of proliferative diseases, autoimmune diseases, and addiction conditions
CN107412161A (en) * 2017-05-22 2017-12-01 河南科技大学 A kind of methoxyestradiol intravenous injection of self-emulsifying 2 and preparation method thereof
WO2025126153A2 (en) * 2023-12-14 2025-06-19 Aviadobio Ltd. Compositions and methods for treating sod1-mediated neurological diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843459A (en) * 1996-01-19 1998-12-01 Human Gene Therapy Research Institute Differential inactivation of nucleic acids by chemical modification
JP2002517449A (en) * 1998-06-10 2002-06-18 ステリックス リミテッド Pharmaceutical composition having tumor necrosis factor A and 2-methoxyestrone-3-O-sulfamate for inhibition of estrone sulfatase
AU783910B2 (en) * 1999-04-30 2005-12-22 Sterix Limited Use of estrone derivatives as antitumour agents
GB9913536D0 (en) * 1999-06-10 1999-08-11 Sterix Ltd Use
US6420378B1 (en) * 1999-10-15 2002-07-16 Supergen, Inc. Inhibition of abnormal cell proliferation with camptothecin and combinations including the same

Also Published As

Publication number Publication date
WO2002003979A3 (en) 2003-07-24
US20020106348A1 (en) 2002-08-08
WO2002003979A2 (en) 2002-01-17

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