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AU2001273234A1 - Method and system for consistent and effective encapsulation of biological material - Google Patents

Method and system for consistent and effective encapsulation of biological material

Info

Publication number
AU2001273234A1
AU2001273234A1 AU2001273234A AU7323401A AU2001273234A1 AU 2001273234 A1 AU2001273234 A1 AU 2001273234A1 AU 2001273234 A AU2001273234 A AU 2001273234A AU 7323401 A AU7323401 A AU 7323401A AU 2001273234 A1 AU2001273234 A1 AU 2001273234A1
Authority
AU
Australia
Prior art keywords
consistent
biological material
effective encapsulation
encapsulation
effective
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001273234A
Other languages
English (en)
Inventor
Monte R. Canfield
Nancy J. Drake
Stephen E. Walsh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Islet Technology Inc
Original Assignee
Islet Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Islet Technology Inc filed Critical Islet Technology Inc
Publication of AU2001273234A1 publication Critical patent/AU2001273234A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B01J13/046—Making microcapsules or microballoons by physical processes, e.g. drying, spraying combined with gelification or coagulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AU2001273234A 2000-07-05 2001-07-05 Method and system for consistent and effective encapsulation of biological material Abandoned AU2001273234A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21594700P 2000-07-05 2000-07-05
US60/215,947 2000-07-05
PCT/US2001/021431 WO2002002745A2 (fr) 2000-07-05 2001-07-05 Procede et un systeme efficace et regulier d'encapsulation de materiaux biologiques

Publications (1)

Publication Number Publication Date
AU2001273234A1 true AU2001273234A1 (en) 2002-01-14

Family

ID=22805046

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001273234A Abandoned AU2001273234A1 (en) 2000-07-05 2001-07-05 Method and system for consistent and effective encapsulation of biological material

Country Status (3)

Country Link
US (2) US6649384B2 (fr)
AU (1) AU2001273234A1 (fr)
WO (1) WO2002002745A2 (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1337830A2 (fr) 2000-12-01 2003-08-27 Auburn University Utilisation de la gomme d'acacia pour isoler et conserver une substance biologique
DE10345342A1 (de) * 2003-09-19 2005-04-28 Engelhard Arzneimittel Gmbh Verfahren zur Herstellung eines lagerstabilen Extraktes aus Efeublättern, sowie ein nach diesem Verfahren hergestellter Extrakt
SE526959C2 (sv) 2003-10-02 2005-11-29 Tikomed Ab Bioartificellt implantat innefattande en semipermeabel barriär samt förfarande för reducering av risken för bildning av bindrväv vid implantatet efter implantering genom att barriären förses med en permeabel beläggning av bioaktiv metall
DE102004019241A1 (de) * 2004-04-16 2005-11-03 Cellmed Ag Injizierbare vernetzte und unvernetzte Alginate und ihre Verwendung in der Medizin und in der ästhetischen Chirurgie
US7723086B2 (en) * 2004-06-16 2010-05-25 Agency For Science, Technology + Research Apparatus for encapsulating cells
US8202701B2 (en) * 2004-10-08 2012-06-19 Georgia Tech Research Corporation Microencapsulation of cells in hydrogels using electrostatic potentials
DE102004055729A1 (de) * 2004-11-18 2006-05-24 Cellmed Ag Herstellung von zwei-oder mehrschichtig aufgebauten Mikrokapseln
US7851189B2 (en) * 2005-03-07 2010-12-14 Boston Scientific Scimed, Inc. Microencapsulated compositions for endoluminal tissue engineering
US7261529B2 (en) * 2005-09-07 2007-08-28 Southwest Research Institute Apparatus for preparing biodegradable microparticle formulations containing pharmaceutically active agents
US7758778B2 (en) * 2005-09-07 2010-07-20 Southwest Research Institute Methods for preparing biodegradable microparticle formulations containing pharmaceutically active agents
US9693967B2 (en) * 2005-09-07 2017-07-04 Southwest Research Institute Biodegradable microparticle pharmaceutical formulations exhibiting improved released rates
US20070134209A1 (en) * 2005-12-12 2007-06-14 Metafluidics, Inc. Cellular encapsulation for self-assembly of engineered tissue
WO2008007383A1 (fr) * 2006-07-14 2008-01-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Gels hydrocolloïdaux électrisés séchés ayant une structure et uene porosité exceptionnelles
US8821431B2 (en) 2007-09-07 2014-09-02 Beta O2 Technologies Ltd. Air gap for supporting cells
CA2730528C (fr) * 2008-07-16 2018-06-12 Kbi Biopharma, Inc. Procedes et systemes de manipulation de particules a l'aide d'un lit fluidise
WO2010032242A1 (fr) * 2008-09-17 2010-03-25 Beta O2 Technologies Ltd. Optimisation de l'encapsulation dans de l'alginate d'îlots à transplanter
GB0918564D0 (en) * 2009-10-22 2009-12-09 Plasticell Ltd Nested cell encapsulation
WO2011154941A2 (fr) * 2010-06-07 2011-12-15 Beta-O2 Technologies Ltd. Barrière immunitaire multicouche pour cellules donneuses
GB201301648D0 (en) * 2013-01-30 2013-03-13 Cambridge Entpr Ltd Nested supramolecular capsules
GB201707143D0 (en) 2017-05-04 2017-06-21 Plasticell Ltd Method for producing cells
DE102017118686A1 (de) * 2017-08-16 2019-02-21 Aesculap Ag Verfahren zur Zustandserfassung an Passivierungsschichten einer Verkapselung
TWI657834B (zh) * 2017-09-21 2019-05-01 緯創資通股份有限公司 自動化移液設備及其移液模組
CN108160014A (zh) * 2018-02-07 2018-06-15 南昌大学 一种制备双层外壳微胶囊装置
CN108272119A (zh) * 2018-02-07 2018-07-13 南昌大学 一种通过温控固化制备微胶囊的装置
CN108543503B (zh) * 2018-05-10 2021-05-11 上海理工大学 一种微胶囊生成装置
US20210163868A1 (en) 2018-05-22 2021-06-03 Nantkwest, Inc. Methods and systems for cell bed formation during bioprocessing
CN111036154A (zh) * 2018-10-12 2020-04-21 中国科学院大连化学物理研究所 基于双水相体系的海藻酸钠-壳聚糖复合微囊制备方法
CN109772240B (zh) * 2019-01-31 2024-03-12 浙江圣兆药物科技股份有限公司 一种用于将液体物料产生微滴的转盘装置及用于制造微球的设备
CN110090605B (zh) * 2019-05-14 2024-05-10 黄琛 一种功能性纳米微球的制备设备
US20250101405A1 (en) * 2023-09-26 2025-03-27 Battelle Memorial Institute Methods for production of microalginate beads and uses for encapsulation

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3160686A (en) 1962-08-01 1964-12-08 Delavan Mfg Company Process for making capsules
US3313608A (en) 1964-12-11 1967-04-11 Corning Glass Works Method and apparatus for manufacturing glass beads
US4391909A (en) 1979-03-28 1983-07-05 Damon Corporation Microcapsules containing viable tissue cells
US4352883A (en) 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4409331A (en) 1979-03-28 1983-10-11 Damon Corporation Preparation of substances with encapsulated cells
US4407957A (en) 1981-03-13 1983-10-04 Damon Corporation Reversible microencapsulation of a core material
CA1196862A (fr) 1983-06-01 1985-11-19 Anthony M.F. Sun Microencapsulement de cellules et de tissus vivants
US4806355A (en) 1983-06-06 1989-02-21 Connaught Laboratories Limited Microencapsulation of living tissue and cells
US4689293A (en) 1983-06-06 1987-08-25 Connaught Laboratories Limited Microencapsulation of living tissue and cells
US4803168A (en) 1983-09-01 1989-02-07 Damon Biotech, Inc. Microencapsulation with polymers
US4663286A (en) 1984-02-13 1987-05-05 Damon Biotech, Inc. Encapsulation of materials
CA1215922A (fr) 1984-05-25 1986-12-30 Connaught Laboratories Limited Microencapsulation de cellules et de tissus vivants
US4956128A (en) 1984-05-25 1990-09-11 Connaught Laboratories Limited Droplet generation
NO166836C (no) 1985-03-14 1991-09-11 Univ California Fremgangsmaate for behandling av et organtransplantat.
JPS63134523A (ja) * 1986-11-22 1988-06-07 Chisso Corp 針状α−オキシ水酸化鉄粒子粉末の製造方法
US5227298A (en) 1990-08-17 1993-07-13 The Trustees Of Columbia University In The City Of New York Method for microencapuslation of cells or tissue
CA2125483A1 (fr) * 1991-12-11 1993-06-24 Mary Ann Hunter Chlorure de cetylpyridinium et bromure de domiphene dans un solvant organique
US5260002A (en) 1991-12-23 1993-11-09 Vanderbilt University Method and apparatus for producing uniform polymeric spheres
US5286495A (en) 1992-05-11 1994-02-15 University Of Florida Process for microencapsulating cells
ATE207727T1 (de) 1992-05-29 2001-11-15 Univ California Beschichtetes transplantat sowie herstellungsverfahren dafür
WO1994013266A1 (fr) 1992-05-29 1994-06-23 The Regents Of The University Of California Nouveau procede electrostatique de realisation de transplants a revetement et produits ainsi realises
US5521079A (en) 1994-01-24 1996-05-28 The Regents Of The University Of California Microcapsule generating system containing an air knife and method of encapsulating
US5429821A (en) 1992-05-29 1995-07-04 The Regents Of The University Of California Non-fibrogenic high mannuronate alginate coated transplants, processes for their manufacture, and methods for their use
US6001387A (en) * 1992-05-29 1999-12-14 The Reguents Of The University Of California Spin disk encapsulation apparatus and method of use
US5643594A (en) * 1992-05-29 1997-07-01 The Regents Of The University Of California Spin encapsulation apparatus and method of use
US5578314A (en) * 1992-05-29 1996-11-26 The Regents Of The University Of California Multiple layer alginate coatings of biological tissue for transplantation
US5876742A (en) 1994-01-24 1999-03-02 The Regents Of The University Of California Biological tissue transplant coated with stabilized multilayer alginate coating suitable for transplantation and method of preparation thereof
US5514377A (en) 1994-03-08 1996-05-07 The Regents Of The University Of California In situ dissolution of alginate coatings of biological tissue transplants
US5916790A (en) 1995-03-03 1999-06-29 Metabolex, Inc. Encapsulation compositions, and methods
US5679565A (en) 1995-04-10 1997-10-21 The Regents Of The University Of California Method of preserving pancreatic islets

Also Published As

Publication number Publication date
US20020022016A1 (en) 2002-02-21
WO2002002745A2 (fr) 2002-01-10
US6649384B2 (en) 2003-11-18
WO2002002745A3 (fr) 2003-01-30
US20040048358A1 (en) 2004-03-11

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