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AU2001272935A1 - Cobalamin compounds useful as antibiotic agents and as imaging agents - Google Patents

Cobalamin compounds useful as antibiotic agents and as imaging agents

Info

Publication number
AU2001272935A1
AU2001272935A1 AU2001272935A AU7293501A AU2001272935A1 AU 2001272935 A1 AU2001272935 A1 AU 2001272935A1 AU 2001272935 A AU2001272935 A AU 2001272935A AU 7293501 A AU7293501 A AU 7293501A AU 2001272935 A1 AU2001272935 A1 AU 2001272935A1
Authority
AU
Australia
Prior art keywords
agents
compounds useful
antibiotic
imaging
cobalamin compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001272935A
Inventor
Douglas A. Collins
Henricus P. C. Hogenkamp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Minnesota System
Mayo Clinic in Florida
Original Assignee
Mayo Foundation for Medical Education and Research
University of Minnesota Twin Cities
University of Minnesota System
Mayo Clinic in Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mayo Foundation for Medical Education and Research, University of Minnesota Twin Cities, University of Minnesota System, Mayo Clinic in Florida filed Critical Mayo Foundation for Medical Education and Research
Publication of AU2001272935A1 publication Critical patent/AU2001272935A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2001272935A 2000-05-31 2001-05-31 Cobalamin compounds useful as antibiotic agents and as imaging agents Abandoned AU2001272935A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US20814800P 2000-05-31 2000-05-31
US60208148 2000-05-31
US26754301P 2001-02-09 2001-02-09
US60267543 2001-02-09
PCT/US2001/017989 WO2001092288A2 (en) 2000-05-31 2001-05-31 Cobalamin compounds useful as antibiotic agents and as imaging agents

Publications (1)

Publication Number Publication Date
AU2001272935A1 true AU2001272935A1 (en) 2001-12-11

Family

ID=26902941

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001272935A Abandoned AU2001272935A1 (en) 2000-05-31 2001-05-31 Cobalamin compounds useful as antibiotic agents and as imaging agents

Country Status (3)

Country Link
US (1) US20020042394A1 (en)
AU (1) AU2001272935A1 (en)
WO (1) WO2001092288A2 (en)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5739313A (en) * 1995-11-13 1998-04-14 Regents Of The University Of Minnesota Radionuclide labeling of vitamin B12 and coenzymes thereof
US6806363B1 (en) * 1999-04-16 2004-10-19 Mayo Foundation For Medical Education & Research Cobalamin conjugates useful as antitumor agents
EP1239887A1 (en) 1999-10-15 2002-09-18 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging and therapeutic agents
US7591995B2 (en) * 1999-10-15 2009-09-22 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging and therapeutic agents
JP2003512338A (en) * 1999-10-15 2003-04-02 メイオウ・フアウンデーシヨン・フオー・メデイカル・エジユケイシヨン・アンド・リサーチ Cobalamin conjugates useful as contrast agents and antitumor agents
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
BR0109544A (en) * 2000-03-28 2003-06-10 Biochemie Gmbh Granules with hidden flavor
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
TWI228512B (en) 2000-10-25 2005-03-01 Mayo Foundation Transcobalamin binding conjugates useful for treating abnormal cellular proliferation
US20030144198A1 (en) * 2001-09-28 2003-07-31 Collins Douglas A. Coadministration of transport protein with conjugated cobalamin to deliver agents
US20040170687A1 (en) * 2003-02-27 2004-09-02 Integrity Pharmaceutical Corporation Compositions with improved stability and methods of formulation thereof
AU2004236603B2 (en) * 2003-05-07 2006-12-07 Eisai R & D Management Co., Ltd. Freeze-dried preparation containing methylcobalamin and process for producing the same
WO2005009365A2 (en) 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
US8425936B2 (en) * 2003-07-21 2013-04-23 Shionogi Inc. Antibiotic product, use and formulation thereof
CA2533292C (en) * 2003-07-21 2013-12-31 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
WO2005016311A1 (en) * 2003-08-11 2005-02-24 Advancis Pharmaceutical Corporation Robust pellet
CA2535398C (en) * 2003-08-12 2013-11-12 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
AU2004270170B2 (en) 2003-08-29 2011-01-27 Shionogi, Inc. Antibiotic product, use and formulation thereof
US9149440B2 (en) * 2003-09-02 2015-10-06 University Of South Florida Nanoparticles for drug-delivery
US7232805B2 (en) * 2003-09-10 2007-06-19 Inflabloc Pharmaceuticals, Inc. Cobalamin conjugates for anti-tumor therapy
US8460710B2 (en) 2003-09-15 2013-06-11 Shionogi, Inc. Antibiotic product, use and formulation thereof
JP2007517039A (en) * 2003-12-24 2007-06-28 アドバンシス ファーマスーティカル コーポレイション Enhanced absorption of modified release formulations
US8715727B2 (en) 2004-07-02 2014-05-06 Shionogi Inc. Tablet for pulsed delivery
US20060110787A1 (en) * 2004-11-19 2006-05-25 The Board Trustees Of The University Of Arkansas Use of fluorine-18-labeled fluoroquinolone antibiotics for diagnosing and monitoring bacterial infection
US8535750B2 (en) * 2005-05-17 2013-09-17 Cargill, Incorporated Granular lecithins, granular lysolecithins, process for their production and compositions containing them
WO2007037790A2 (en) * 2005-06-08 2007-04-05 Elan Corporation, Plc Modified release famciclovir compositions
US8778924B2 (en) * 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
KR100806368B1 (en) 2006-03-10 2008-02-27 최원식 Radionuclide-pyrazineamide Compositions and Kits thereof as a Tuberculosis Nuclear Medicine Imaging Contrast Agent
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
US8414926B1 (en) * 2006-09-12 2013-04-09 University Of South Florida Nanoparticles with covalently bound surfactant for drug delivery
US20080214417A1 (en) * 2007-02-07 2008-09-04 University Of Waterloo Lubricant for wear testing of joint replacements and associated materials
EP2018864A1 (en) 2007-07-23 2009-01-28 Biomet Deutschland GmbH Pharmaceutical composition, substrate comprising a pharmaceutical composition, and use of a pharmaceutical composition
US9264184B2 (en) * 2009-10-30 2016-02-16 Sony Corporation Coordinated signaling of scheduling information for uplink and downlink communications
US10640457B2 (en) 2009-12-10 2020-05-05 The Trustees Of Columbia University In The City Of New York Histone acetyltransferase activators and uses thereof
KR101799304B1 (en) 2010-05-12 2017-11-20 렘펙스 파머수티클스 인코퍼레이티드 Tetracycline compositions
CN106432137B (en) * 2010-12-22 2020-11-06 纽约市哥伦比亚大学理事会 Histone acetyltransferase modulators and uses thereof
US10265312B1 (en) * 2018-02-01 2019-04-23 Jason Ahee Antibiotic solution and method of injection to prevent ophthalmic infections
WO2019212377A1 (en) * 2018-05-04 2019-11-07 Farber Boris Slavinovich Polymyxin-based pharmaceutical composition for treating infectious diseases
WO2020081454A1 (en) * 2018-10-15 2020-04-23 The Board Of Trustees Of The Leland Stanford Junior University Multi-enzyme-activated imaging probes and related compositions and methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5449720A (en) * 1993-05-24 1995-09-12 Biotech Australia Pty Limited Amplification of the VB12 uptake system using polymers
US5840880A (en) * 1994-04-08 1998-11-24 Receptagen Corporation Receptor modulating agents
US5574018A (en) * 1994-07-29 1996-11-12 Amgen Inc. Conjugates of vitamin B12 and proteins
WO1998008859A1 (en) * 1996-08-27 1998-03-05 University Of Utah Research Foundation Bioconjugates and delivery of bioactive agents

Also Published As

Publication number Publication date
US20020042394A1 (en) 2002-04-11
WO2001092288A2 (en) 2001-12-06
WO2001092288A3 (en) 2002-06-27

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