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AU2001271664A1 - Method of using reduced dimensionality nmr spectroscopy for rapid chemical shiftassignment and structure determination of proteins - Google Patents

Method of using reduced dimensionality nmr spectroscopy for rapid chemical shiftassignment and structure determination of proteins

Info

Publication number
AU2001271664A1
AU2001271664A1 AU2001271664A AU7166401A AU2001271664A1 AU 2001271664 A1 AU2001271664 A1 AU 2001271664A1 AU 2001271664 A AU2001271664 A AU 2001271664A AU 7166401 A AU7166401 A AU 7166401A AU 2001271664 A1 AU2001271664 A1 AU 2001271664A1
Authority
AU
Australia
Prior art keywords
shiftassignment
proteins
nmr spectroscopy
structure determination
reduced dimensionality
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001271664A
Inventor
Thomas A. Szyperski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Foundation of the State University of New York
Original Assignee
Research Foundation of the State University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Foundation of the State University of New York filed Critical Research Foundation of the State University of New York
Publication of AU2001271664A1 publication Critical patent/AU2001271664A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/46—NMR spectroscopy
    • G01R33/4625—Processing of acquired signals, e.g. elimination of phase errors, baseline fitting, chemometric analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/46—NMR spectroscopy
    • G01R33/4633—Sequences for multi-dimensional NMR
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/46—NMR spectroscopy
    • G01R33/465—NMR spectroscopy applied to biological material, e.g. in vitro testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/46—NMR spectroscopy
    • G01R33/4608—RF excitation sequences for enhanced detection, e.g. NOE, polarisation transfer, selection of a coherence transfer pathway
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU2001271664A 2000-06-30 2001-06-29 Method of using reduced dimensionality nmr spectroscopy for rapid chemical shiftassignment and structure determination of proteins Abandoned AU2001271664A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21564900P 2000-06-30 2000-06-30
US60215649 2000-06-30
PCT/US2001/020805 WO2002003081A2 (en) 2000-06-30 2001-06-29 Method of using reduced dimensionality nmr spectroscopy for rapid chemical shift assignment and structure determination of proteins

Publications (1)

Publication Number Publication Date
AU2001271664A1 true AU2001271664A1 (en) 2002-01-14

Family

ID=22803821

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001271664A Abandoned AU2001271664A1 (en) 2000-06-30 2001-06-29 Method of using reduced dimensionality nmr spectroscopy for rapid chemical shiftassignment and structure determination of proteins

Country Status (5)

Country Link
US (1) US7141432B2 (en)
EP (1) EP1295111A4 (en)
AU (1) AU2001271664A1 (en)
CA (1) CA2413071A1 (en)
WO (1) WO2002003081A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7396685B2 (en) * 2002-07-26 2008-07-08 The Research Foundation Of State University Of New York Phase sensitively-detected reduced dimensionality nuclear magnetic resonance spectroscopy for rapid chemical shift assignment and secondary structure determination of proteins
US20040038216A1 (en) * 2002-08-23 2004-02-26 Hajduk Philip J. Method for the structural determination of ligands bound to macromolecular targets by nuclear magnetic resonance
US7920972B2 (en) * 2004-10-18 2011-04-05 The Research Foundation Of State University Of New York G-matrix Fourier transformation (GFT) nuclear magnetic resonance (NMR) experiments for resonance assignment and structure determination of organic molecules
US7795867B2 (en) * 2006-02-02 2010-09-14 Ramot At Tel-Aviv University Ltd. Method, apparatus and system for magnetic resonance analysis based on water magnetization transferred from other molecules
WO2009018276A1 (en) 2007-07-30 2009-02-05 The Research Foundation Of State University Of New York Simultaneously cycled nmr spectroscopy
US7598738B2 (en) * 2008-03-07 2009-10-06 Varian, Inc. Complete structure elucidation of molecules utilizing single NMR experiment
US8686112B2 (en) 2008-08-14 2014-04-01 Case Western Reserve University Methods and compositions for the detection of cancer
US9170221B2 (en) 2010-10-01 2015-10-27 Elizabeth M. HEIDER NMR crystallography methods for three-dimensional structure determination
WO2015072982A1 (en) * 2013-11-13 2015-05-21 Heider Elizabeth M Nmr crystallography methods for three-dimensional structure determination
CN107064199B (en) * 2017-01-23 2018-12-04 贵州大学 Application of trans-form seven-element cucurbituril in recognition of biogenic amine
CN108344760A (en) * 2018-02-10 2018-07-31 广东东阳光药业有限公司 Liraglutide side chain content determination method
CN109932381B (en) * 2018-09-10 2021-04-27 苏州大学 Method and device for measuring spin lattice relaxation time
EP3974858B1 (en) * 2020-09-29 2023-12-13 Terra Quantum AG Techniques for determining a nuclear magnetic resonance relaxation time and/or a nuclear magnetic resonance spectrum of a probe

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2490305A1 (en) 2002-07-11 2004-01-22 Thomas A. Szyperski A method of using g-matrix fourier transformation nuclear magnetic resonance (gft nmr) spectroscopy for rapid chemical shift assignment and secondary structure determination of proteins
US7396685B2 (en) 2002-07-26 2008-07-08 The Research Foundation Of State University Of New York Phase sensitively-detected reduced dimensionality nuclear magnetic resonance spectroscopy for rapid chemical shift assignment and secondary structure determination of proteins

Also Published As

Publication number Publication date
EP1295111A4 (en) 2004-09-01
WO2002003081A3 (en) 2002-05-23
CA2413071A1 (en) 2002-01-10
WO2002003081A2 (en) 2002-01-10
US7141432B2 (en) 2006-11-28
EP1295111A2 (en) 2003-03-26
US20020041850A1 (en) 2002-04-11
US20030012733A9 (en) 2003-01-16

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