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AU2001270593A1 - Pharmaceutical compositions containing tobramycin and xanthan gum - Google Patents

Pharmaceutical compositions containing tobramycin and xanthan gum

Info

Publication number
AU2001270593A1
AU2001270593A1 AU2001270593A AU7059301A AU2001270593A1 AU 2001270593 A1 AU2001270593 A1 AU 2001270593A1 AU 2001270593 A AU2001270593 A AU 2001270593A AU 7059301 A AU7059301 A AU 7059301A AU 2001270593 A1 AU2001270593 A1 AU 2001270593A1
Authority
AU
Australia
Prior art keywords
pharmaceutical compositions
compositions containing
xanthan gum
containing tobramycin
tobramycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001270593A
Other languages
English (en)
Inventor
Nuria Carreras Perdiguer
Gemma Torrella Cabello
Jose Alberto Vallet Mas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Alcon Universal Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Universal Ltd filed Critical Alcon Universal Ltd
Publication of AU2001270593A1 publication Critical patent/AU2001270593A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AU2001270593A 2000-07-28 2001-06-26 Pharmaceutical compositions containing tobramycin and xanthan gum Abandoned AU2001270593A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22166000P 2000-07-28 2000-07-28
US60221660 2000-07-28
PCT/EP2001/007267 WO2002009724A1 (fr) 2000-07-28 2001-06-26 Compositions pharmaceutiques contenant de la tobramycine et de la gomme de xanthane

Publications (1)

Publication Number Publication Date
AU2001270593A1 true AU2001270593A1 (en) 2002-02-13

Family

ID=22828757

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001270593A Abandoned AU2001270593A1 (en) 2000-07-28 2001-06-26 Pharmaceutical compositions containing tobramycin and xanthan gum

Country Status (18)

Country Link
US (1) US6352978B1 (fr)
EP (1) EP1305033B1 (fr)
CN (1) CN1218689C (fr)
AR (1) AR029965A1 (fr)
AT (1) ATE279927T1 (fr)
AU (1) AU2001270593A1 (fr)
BR (1) BR0112787B1 (fr)
CA (1) CA2414737C (fr)
CO (1) CO5300418A1 (fr)
DE (1) DE60106619T2 (fr)
DK (1) DK1305033T3 (fr)
ES (1) ES2225573T3 (fr)
MX (1) MXPA03000813A (fr)
PL (1) PL199321B1 (fr)
PT (1) PT1305033E (fr)
TW (1) TWI282278B (fr)
WO (1) WO2002009724A1 (fr)
ZA (1) ZA200300110B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1797888A4 (fr) * 2004-09-28 2009-12-16 Senju Pharma Co Composition ophtalmique contenant de la gomme xanthane et un acide amine
US7795316B1 (en) 2007-12-19 2010-09-14 Alcon Research, Ltd. Topical ophthalmic compositions containing tobramycin and dexamethasone
TWI495469B (zh) 2008-06-09 2015-08-11 Alcon Res Ltd 含有氟喹諾酮抗生素藥物之經改良藥學組成物
KR20130094280A (ko) * 2010-06-23 2013-08-23 알콘 리서치, 리미티드 토브라마이신과 덱사메타손을 함유하는 국소 안과 현탁액
US9480696B2 (en) * 2011-05-04 2016-11-01 Trustees Of Boston University Proton-motive force stimulation to potentiate aminoglycoside antibiotics against persistent bacteria

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3700451A (en) 1970-04-06 1972-10-24 Itek Corp Gelable and gelled compositions
US3944427A (en) 1970-04-06 1976-03-16 Itek Corporation Gelable and gelled compositions
US3784712A (en) 1970-12-23 1974-01-08 Gen Foods Corp Gum gelling system xanthan-tara dessert gel
CA1070629A (fr) 1975-11-10 1980-01-29 Allen I. Laskin Procede pour modifier des biopolymeres
US4135979A (en) 1976-08-24 1979-01-23 Merck & Co., Inc. Treatment of xanthan gum to improve clarity
US4136173A (en) 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
US4136178A (en) 1977-01-31 1979-01-23 American Home Products Corp. Locust bean gum therapeutic compositions
US4136177A (en) 1977-01-31 1979-01-23 American Home Products Corp. Xanthan gum therapeutic compositions
GB8318403D0 (en) 1983-07-07 1983-08-10 Sutherland I W Gel-forming polysaccharides
FR2551087B1 (fr) 1983-08-30 1986-03-21 Rhone Poulenc Spec Chim Procede de traitement d'une solution de polysaccharide et son utilisation
DE3335593A1 (de) 1983-09-30 1985-04-11 Diamalt AG, 8000 München Gelier- und verdickungsmittel auf der basis von cassia-galactomannanen
US4717713A (en) 1983-10-31 1988-01-05 Research Corporation Controlled release liquid pharmaceutical
US4708861A (en) 1984-02-15 1987-11-24 The Liposome Company, Inc. Liposome-gel compositions
FR2588189B1 (fr) 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
US4647470A (en) 1985-11-27 1987-03-03 Merck & Co., Inc. Low-acetyl gellan gum blends
FR2618333B1 (fr) 1987-07-20 1990-07-13 Merck Sharp & Dohme Composition pharmaceutique et/ou cosmetique a usage topique contenant de la gomme rhamsam
US5192535A (en) 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
US4814160A (en) 1988-03-01 1989-03-21 Colgate-Palmolive Company Non-bleeding striped dentifrice
US5234957A (en) 1991-02-27 1993-08-10 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5446070A (en) 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5149694A (en) 1988-03-09 1992-09-22 Alcon Laboratories, Inc. Combination of tobramycin and dexamethasone for topical ophthalmic use
DE3843416A1 (de) 1988-12-23 1990-06-28 Wolff Walsrode Ag Xanthan mit verbesserter loeslichkeit und verfahren zur herstellung
CA2021414C (fr) 1989-07-25 2004-09-28 Daniel H. Doherty Controle genetique de l'acetylation et de la pyruvylation de la gomme xanthane
US5461081A (en) 1989-09-28 1995-10-24 Alcon Laboratories, Inc. Topical ophthalmic pharmaceutical vehicles
FR2653021A1 (fr) 1989-10-17 1991-04-19 Merck Sharp & Dohme Composition ophtalmique aqueuse liquide a transition de phase liquide-gel.
JP2594486B2 (ja) 1991-01-15 1997-03-26 アルコン ラボラトリーズ インコーポレイテッド 局所的眼薬組成物
US5212162A (en) 1991-03-27 1993-05-18 Alcon Laboratories, Inc. Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions
CA2064160C (fr) * 1991-03-27 1998-08-11 Paul J. T. Missel Emploi de polysaccharides gelifiants combines a des substrats finement divises a action de vecteur des medicaments, dans des compositions ophthalmiques a usage local
ES2111083T3 (es) 1991-09-17 1998-03-01 Alcon Lab Inc Composiciones que contienen antibioticos de quinolona y poli(sulfonato de estireno).
US5192802A (en) 1991-09-25 1993-03-09 Mcneil-Ppc, Inc. Bioadhesive pharmaceutical carrier
US5318780A (en) 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
US5473062A (en) 1992-10-29 1995-12-05 Takeda Chemical Industries, Ltd. Process for producing purified xanthan gum
JP3228315B2 (ja) 1993-04-23 2001-11-12 信越化学工業株式会社 キサンタンガムの汚染生菌数を減少させる方法
AU1567795A (en) 1994-01-14 1995-08-01 Lee Shahinian Jr. A method for sustained and extended corneal analgesia
US5422116A (en) 1994-02-18 1995-06-06 Ciba-Geigy Corporation Liquid ophthalmic sustained release delivery system
KR100374098B1 (ko) 1994-04-08 2003-06-09 아트릭스 라보라토리스, 인코포레이션 조절된방출이식편형성에적합한액체전달조성물
US5523301A (en) 1994-08-05 1996-06-04 Merck & Co., Inc. Optic nerve health
EP0725628B1 (fr) 1994-08-30 2001-11-07 Alcon Laboratories, Inc. Excipients a gelification thermique contenant des ethers cellulosiques
US5972326A (en) 1995-04-18 1999-10-26 Galin; Miles A. Controlled release of pharmaceuticals in the anterior chamber of the eye
FR2742336B1 (fr) 1995-12-19 1998-03-06 Chauvin Lab Sa Collyre destine notamment au traitement de l'oeil sec
SE9603480L (sv) 1996-09-23 1998-03-24 Johan Carlfors Beredningsform för svårlösliga läkemedel
FR2754712B1 (fr) 1996-10-17 1999-09-03 Merck Sharp Dohme Chibret Lab Compositions ophtalmiques
US5888493A (en) 1996-12-05 1999-03-30 Sawaya; Assad S. Ophthalmic aqueous gel formulation and related methods
JP2002501533A (ja) 1997-05-30 2002-01-15 メルク エンド カンパニー インコーポレーテッド 高眼圧症治療のための眼科用組成物
KR20010013377A (fr) * 1997-06-04 2001-02-26 데이비드 엠 모이어 Compositions antimicrobiennes comprenant un analogue de l'acide benzoique et un sel metallique
WO1999000133A1 (fr) 1997-06-26 1999-01-07 Merck & Co., Inc. Procede permettant d'optimiser l'etat de sante de la retine et du nerf optique
DK1069913T3 (da) * 1998-04-07 2003-11-17 Alcon Mfg Ltd Gelatinering af ophthalmiske sammensætninger indeholdende xanthangummi
US6174524B1 (en) * 1999-03-26 2001-01-16 Alcon Laboratories, Inc. Gelling ophthalmic compositions containing xanthan gum
US6297337B1 (en) * 1999-05-19 2001-10-02 Pmd Holdings Corp. Bioadhesive polymer compositions

Also Published As

Publication number Publication date
CN1444482A (zh) 2003-09-24
AR029965A1 (es) 2003-07-23
BR0112787B1 (pt) 2013-03-05
DE60106619D1 (de) 2004-11-25
US20020035088A1 (en) 2002-03-21
WO2002009724A1 (fr) 2002-02-07
PL365154A1 (en) 2004-12-27
BR0112787A (pt) 2003-09-09
US6352978B1 (en) 2002-03-05
DK1305033T3 (da) 2005-01-31
ZA200300110B (en) 2004-01-21
EP1305033B1 (fr) 2004-10-20
CA2414737A1 (fr) 2002-02-07
CN1218689C (zh) 2005-09-14
ATE279927T1 (de) 2004-11-15
PL199321B1 (pl) 2008-09-30
PT1305033E (pt) 2005-01-31
MXPA03000813A (es) 2005-08-16
CO5300418A1 (es) 2003-07-31
EP1305033A1 (fr) 2003-05-02
DE60106619T2 (de) 2005-03-17
CA2414737C (fr) 2009-01-06
TWI282278B (en) 2007-06-11
ES2225573T3 (es) 2005-03-16

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