AU2001270593A1 - Pharmaceutical compositions containing tobramycin and xanthan gum - Google Patents
Pharmaceutical compositions containing tobramycin and xanthan gumInfo
- Publication number
- AU2001270593A1 AU2001270593A1 AU2001270593A AU7059301A AU2001270593A1 AU 2001270593 A1 AU2001270593 A1 AU 2001270593A1 AU 2001270593 A AU2001270593 A AU 2001270593A AU 7059301 A AU7059301 A AU 7059301A AU 2001270593 A1 AU2001270593 A1 AU 2001270593A1
- Authority
- AU
- Australia
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- xanthan gum
- containing tobramycin
- tobramycin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- NLVFBUXFDBBNBW-PBSUHMDJSA-N tobramycin Chemical compound N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N NLVFBUXFDBBNBW-PBSUHMDJSA-N 0.000 title 1
- 229960000707 tobramycin Drugs 0.000 title 1
- 229920001285 xanthan gum Polymers 0.000 title 1
- 229940082509 xanthan gum Drugs 0.000 title 1
- 235000010493 xanthan gum Nutrition 0.000 title 1
- 239000000230 xanthan gum Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22166000P | 2000-07-28 | 2000-07-28 | |
| US60221660 | 2000-07-28 | ||
| PCT/EP2001/007267 WO2002009724A1 (en) | 2000-07-28 | 2001-06-26 | Pharmaceutical compositions containing tobramycin and xanthan gum |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001270593A1 true AU2001270593A1 (en) | 2002-02-13 |
Family
ID=22828757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001270593A Abandoned AU2001270593A1 (en) | 2000-07-28 | 2001-06-26 | Pharmaceutical compositions containing tobramycin and xanthan gum |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6352978B1 (da) |
| EP (1) | EP1305033B1 (da) |
| CN (1) | CN1218689C (da) |
| AR (1) | AR029965A1 (da) |
| AT (1) | ATE279927T1 (da) |
| AU (1) | AU2001270593A1 (da) |
| BR (1) | BR0112787B1 (da) |
| CA (1) | CA2414737C (da) |
| CO (1) | CO5300418A1 (da) |
| DE (1) | DE60106619T2 (da) |
| DK (1) | DK1305033T3 (da) |
| ES (1) | ES2225573T3 (da) |
| MX (1) | MXPA03000813A (da) |
| PL (1) | PL199321B1 (da) |
| PT (1) | PT1305033E (da) |
| TW (1) | TWI282278B (da) |
| WO (1) | WO2002009724A1 (da) |
| ZA (1) | ZA200300110B (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101301839B1 (ko) * | 2004-09-28 | 2013-08-29 | 센주 세이야꾸 가부시키가이샤 | 잔탄 검 및 아미노산을 함유하는 안과용 조성물 |
| US7795316B1 (en) | 2007-12-19 | 2010-09-14 | Alcon Research, Ltd. | Topical ophthalmic compositions containing tobramycin and dexamethasone |
| TWI544934B (zh) * | 2008-06-09 | 2016-08-11 | 愛爾康研究有限公司 | 含有氟喹諾酮抗生素藥物之經改良藥學組成物 |
| JP5728082B2 (ja) * | 2010-06-23 | 2015-06-03 | アルコン リサーチ， リミテッド | トブラマイシンおよびデキサメタゾンを含む局所用眼用懸濁液 |
| US9480696B2 (en) | 2011-05-04 | 2016-11-01 | Trustees Of Boston University | Proton-motive force stimulation to potentiate aminoglycoside antibiotics against persistent bacteria |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3700451A (en) | 1970-04-06 | 1972-10-24 | Itek Corp | Gelable and gelled compositions |
| US3944427A (en) | 1970-04-06 | 1976-03-16 | Itek Corporation | Gelable and gelled compositions |
| US3784712A (en) | 1970-12-23 | 1974-01-08 | Gen Foods Corp | Gum gelling system xanthan-tara dessert gel |
| CA1070629A (en) | 1975-11-10 | 1980-01-29 | Allen I. Laskin | Process for modifying biopolymers |
| US4135979A (en) | 1976-08-24 | 1979-01-23 | Merck & Co., Inc. | Treatment of xanthan gum to improve clarity |
| US4136178A (en) | 1977-01-31 | 1979-01-23 | American Home Products Corp. | Locust bean gum therapeutic compositions |
| US4136177A (en) | 1977-01-31 | 1979-01-23 | American Home Products Corp. | Xanthan gum therapeutic compositions |
| US4136173A (en) | 1977-01-31 | 1979-01-23 | American Home Products Corp. | Mixed xanthan gum and locust beam gum therapeutic compositions |
| GB8318403D0 (en) | 1983-07-07 | 1983-08-10 | Sutherland I W | Gel-forming polysaccharides |
| FR2551087B1 (fr) | 1983-08-30 | 1986-03-21 | Rhone Poulenc Spec Chim | Procede de traitement d'une solution de polysaccharide et son utilisation |
| DE3335593A1 (de) | 1983-09-30 | 1985-04-11 | Diamalt AG, 8000 München | Gelier- und verdickungsmittel auf der basis von cassia-galactomannanen |
| US4717713A (en) | 1983-10-31 | 1988-01-05 | Research Corporation | Controlled release liquid pharmaceutical |
| US4708861A (en) | 1984-02-15 | 1987-11-24 | The Liposome Company, Inc. | Liposome-gel compositions |
| FR2588189B1 (fr) | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| US4647470A (en) | 1985-11-27 | 1987-03-03 | Merck & Co., Inc. | Low-acetyl gellan gum blends |
| FR2618333B1 (fr) | 1987-07-20 | 1990-07-13 | Merck Sharp & Dohme | Composition pharmaceutique et/ou cosmetique a usage topique contenant de la gomme rhamsam |
| US5192535A (en) | 1988-02-08 | 1993-03-09 | Insite Vision Incorporated | Ophthalmic suspensions |
| US4814160A (en) | 1988-03-01 | 1989-03-21 | Colgate-Palmolive Company | Non-bleeding striped dentifrice |
| US5446070A (en) | 1991-02-27 | 1995-08-29 | Nover Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| US5234957A (en) | 1991-02-27 | 1993-08-10 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| US5149694A (en) | 1988-03-09 | 1992-09-22 | Alcon Laboratories, Inc. | Combination of tobramycin and dexamethasone for topical ophthalmic use |
| DE3843416A1 (de) | 1988-12-23 | 1990-06-28 | Wolff Walsrode Ag | Xanthan mit verbesserter loeslichkeit und verfahren zur herstellung |
| CA2021414C (en) | 1989-07-25 | 2004-09-28 | Daniel H. Doherty | Genetic control of acetylation and pyruvylation of xanthan gum |
| US5461081A (en) | 1989-09-28 | 1995-10-24 | Alcon Laboratories, Inc. | Topical ophthalmic pharmaceutical vehicles |
| FR2653021A1 (fr) | 1989-10-17 | 1991-04-19 | Merck Sharp & Dohme | Composition ophtalmique aqueuse liquide a transition de phase liquide-gel. |
| ATE141502T1 (de) | 1991-01-15 | 1996-09-15 | Alcon Lab Inc | Verwendung von karrageenan in topischen ophthalmologischen zusammensetzungen |
| JP2536806B2 (ja) * | 1991-03-27 | 1996-09-25 | アルコン ラボラトリーズ インコーポレイテッド | ゲル化多糖類と微粉砕された薬剤担体とを組み合わせた局部眼科用組成物 |
| US5212162A (en) | 1991-03-27 | 1993-05-18 | Alcon Laboratories, Inc. | Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions |
| AU2672892A (en) | 1991-09-17 | 1993-04-27 | Alcon Laboratories, Inc. | Compositions containing quinolone antibiotics and sulfonate of polystyrol |
| US5192802A (en) | 1991-09-25 | 1993-03-09 | Mcneil-Ppc, Inc. | Bioadhesive pharmaceutical carrier |
| US5318780A (en) | 1991-10-30 | 1994-06-07 | Mediventures Inc. | Medical uses of in situ formed gels |
| US5473062A (en) | 1992-10-29 | 1995-12-05 | Takeda Chemical Industries, Ltd. | Process for producing purified xanthan gum |
| JP3228315B2 (ja) | 1993-04-23 | 2001-11-12 | 信越化学工業株式会社 | キサンタンガムの汚染生菌数を減少させる方法 |
| CA2181048C (en) | 1994-01-14 | 2003-05-06 | Lee Shahinian, Jr. | A method for sustained and extended corneal analgesia |
| US5422116A (en) | 1994-02-18 | 1995-06-06 | Ciba-Geigy Corporation | Liquid ophthalmic sustained release delivery system |
| DK1125577T3 (da) | 1994-04-08 | 2006-06-19 | Qlt Usa Inc | Væskeformige medikamentindföringspræparater |
| US5523301A (en) | 1994-08-05 | 1996-06-04 | Merck & Co., Inc. | Optic nerve health |
| DK0725628T3 (da) | 1994-08-30 | 2001-12-27 | Alcon Lab Inc | Termisk geldannende lægemiddelindgivelsesvehikler indeholdende celluloseethere |
| US5972326A (en) | 1995-04-18 | 1999-10-26 | Galin; Miles A. | Controlled release of pharmaceuticals in the anterior chamber of the eye |
| FR2742336B1 (fr) | 1995-12-19 | 1998-03-06 | Chauvin Lab Sa | Collyre destine notamment au traitement de l'oeil sec |
| SE9603480L (sv) | 1996-09-23 | 1998-03-24 | Johan Carlfors | Beredningsform för svårlösliga läkemedel |
| FR2754712B1 (fr) | 1996-10-17 | 1999-09-03 | Merck Sharp Dohme Chibret Lab | Compositions ophtalmiques |
| US5888493A (en) | 1996-12-05 | 1999-03-30 | Sawaya; Assad S. | Ophthalmic aqueous gel formulation and related methods |
| CA2291777A1 (en) | 1997-05-30 | 1998-12-03 | Merck & Co., Inc. | Ophthalmic compositions for treating ocular hypertension |
| KR20010013377A (ko) * | 1997-06-04 | 2001-02-26 | 데이비드 엠 모이어 | 마일드한 잔류성 항균 조성물 |
| EP1024810A4 (en) | 1997-06-26 | 2003-06-11 | Merck & Co Inc | METHOD FOR OPTIMIZING RETINAL AND THE HEALTH OF THE OPTICAL NERVE |
| KR100598722B1 (ko) * | 1998-04-07 | 2006-07-11 | 알콘 래보레이토리스, 인코퍼레이티드 | 잔탄 검을 포함하는 겔화 안과용 조성물 |
| US6174524B1 (en) * | 1999-03-26 | 2001-01-16 | Alcon Laboratories, Inc. | Gelling ophthalmic compositions containing xanthan gum |
| US6297337B1 (en) * | 1999-05-19 | 2001-10-02 | Pmd Holdings Corp. | Bioadhesive polymer compositions |
-
2001
- 2001-06-26 EP EP01949437A patent/EP1305033B1/en not_active Expired - Lifetime
- 2001-06-26 AU AU2001270593A patent/AU2001270593A1/en not_active Abandoned
- 2001-06-26 ES ES01949437T patent/ES2225573T3/es not_active Expired - Lifetime
- 2001-06-26 MX MXPA03000813A patent/MXPA03000813A/es active IP Right Grant
- 2001-06-26 DE DE60106619T patent/DE60106619T2/de not_active Expired - Lifetime
- 2001-06-26 AT AT01949437T patent/ATE279927T1/de active
- 2001-06-26 CN CNB018135285A patent/CN1218689C/zh not_active Expired - Fee Related
- 2001-06-26 PT PT01949437T patent/PT1305033E/pt unknown
- 2001-06-26 BR BRPI0112787-0A patent/BR0112787B1/pt not_active IP Right Cessation
- 2001-06-26 CA CA002414737A patent/CA2414737C/en not_active Expired - Fee Related
- 2001-06-26 WO PCT/EP2001/007267 patent/WO2002009724A1/en not_active Ceased
- 2001-06-26 PL PL365154A patent/PL199321B1/pl unknown
- 2001-06-26 DK DK01949437T patent/DK1305033T3/da active
- 2001-07-11 US US09/902,844 patent/US6352978B1/en not_active Expired - Fee Related
- 2001-07-12 TW TW090117057A patent/TWI282278B/zh not_active IP Right Cessation
- 2001-07-23 AR ARP010103512A patent/AR029965A1/es unknown
- 2001-07-25 CO CO01060485A patent/CO5300418A1/es not_active Application Discontinuation
-
2003
- 2003-01-06 ZA ZA200300110A patent/ZA200300110B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60106619D1 (de) | 2004-11-25 |
| US20020035088A1 (en) | 2002-03-21 |
| DK1305033T3 (da) | 2005-01-31 |
| AR029965A1 (es) | 2003-07-23 |
| TWI282278B (en) | 2007-06-11 |
| EP1305033A1 (en) | 2003-05-02 |
| CA2414737C (en) | 2009-01-06 |
| CA2414737A1 (en) | 2002-02-07 |
| CO5300418A1 (es) | 2003-07-31 |
| MXPA03000813A (es) | 2005-08-16 |
| BR0112787B1 (pt) | 2013-03-05 |
| ATE279927T1 (de) | 2004-11-15 |
| PT1305033E (pt) | 2005-01-31 |
| CN1218689C (zh) | 2005-09-14 |
| US6352978B1 (en) | 2002-03-05 |
| PL365154A1 (en) | 2004-12-27 |
| ZA200300110B (en) | 2004-01-21 |
| DE60106619T2 (de) | 2005-03-17 |
| PL199321B1 (pl) | 2008-09-30 |
| BR0112787A (pt) | 2003-09-09 |
| EP1305033B1 (en) | 2004-10-20 |
| CN1444482A (zh) | 2003-09-24 |
| WO2002009724A1 (en) | 2002-02-07 |
| ES2225573T3 (es) | 2005-03-16 |
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