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AU2001269769A1 - Methods for making bis-heterocyclic alkaloids - Google Patents

Methods for making bis-heterocyclic alkaloids

Info

Publication number
AU2001269769A1
AU2001269769A1 AU2001269769A AU6976901A AU2001269769A1 AU 2001269769 A1 AU2001269769 A1 AU 2001269769A1 AU 2001269769 A AU2001269769 A AU 2001269769A AU 6976901 A AU6976901 A AU 6976901A AU 2001269769 A1 AU2001269769 A1 AU 2001269769A1
Authority
AU
Australia
Prior art keywords
methods
making bis
alkaloids
heterocyclic
heterocyclic alkaloids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001269769A
Inventor
David A Horne
Kenichi Yakushijin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oregon State University
Original Assignee
Oregon State Board of Higher Education
Oregon State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oregon State Board of Higher Education, Oregon State filed Critical Oregon State Board of Higher Education
Publication of AU2001269769A1 publication Critical patent/AU2001269769A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001269769A 2000-06-07 2001-06-07 Methods for making bis-heterocyclic alkaloids Abandoned AU2001269769A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21014500P 2000-06-07 2000-06-07
US60210145 2000-06-07
US22127700P 2000-07-27 2000-07-27
US60221277 2000-07-27
PCT/US2001/018584 WO2001094310A1 (en) 2000-06-07 2001-06-07 Methods for making bis-heterocyclic alkaloids

Publications (1)

Publication Number Publication Date
AU2001269769A1 true AU2001269769A1 (en) 2001-12-17

Family

ID=26904863

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001269769A Abandoned AU2001269769A1 (en) 2000-06-07 2001-06-07 Methods for making bis-heterocyclic alkaloids

Country Status (3)

Country Link
US (1) US6841685B2 (en)
AU (1) AU2001269769A1 (en)
WO (1) WO2001094310A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19828113A1 (en) 1998-06-24 2000-01-05 Probiodrug Ges Fuer Arzneim Prodrugs of Dipeptidyl Peptidase IV Inhibitors
DE19940130A1 (en) 1999-08-24 2001-03-01 Probiodrug Ges Fuer Arzneim New effectors of Dipeptidyl Peptidase IV for topical use
DE10037310A1 (en) 2000-07-28 2002-02-07 Asta Medica Ag New indole derivatives and their use as medicines
US20030130199A1 (en) 2001-06-27 2003-07-10 Von Hoersten Stephan Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
DE10154689A1 (en) * 2001-11-09 2003-05-22 Probiodrug Ag Substituted amino ketone compounds
US7368421B2 (en) 2001-06-27 2008-05-06 Probiodrug Ag Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis
US6844316B2 (en) 2001-09-06 2005-01-18 Probiodrug Ag Inhibitors of dipeptidyl peptidase I
ZA200508439B (en) 2003-05-05 2007-03-28 Probiodrug Ag Medical use of inhibitors of glutaminyl and glutamate cyclases
DE602004026712D1 (en) 2003-05-05 2010-06-02 Probiodrug Ag MEDICAL USE OF INHIBITORS OF GLUTAMINYL AND GLUTAMATE CYCLASES
US7405210B2 (en) 2003-05-21 2008-07-29 Osi Pharmaceuticals, Inc. Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase
CN102302781A (en) 2003-10-15 2012-01-04 前体生物药物股份公司 Medical use of inhibitors of glutaminyl and glutamate cyclases
ES2353309T3 (en) 2004-03-08 2011-03-01 Prosidion Ltd. HYDRAZIDS OF THE PIRROLOPIRIDIN-2-CARBOXYL ACID AS INHIBITORS OF GLUCOGEN PHOSPHORILASE.
EP1819332B1 (en) 2004-12-02 2009-03-11 Prosidion Limited Pyrrolopyridine-2-carboxylic acid amides
CN1331854C (en) * 2005-01-27 2007-08-15 中国科学院上海有机化学研究所 a-methyl-beta,-beta-double indolene compound, synthesis and use thereof
WO2016023106A1 (en) * 2014-08-15 2016-02-18 The University Of British Columbia Bis-indole alkaloids for use in the treatment of infections
BR112022015379A2 (en) 2020-02-04 2022-09-27 Mindset Pharma Inc 3-PYRROLIDINO-INDOLE DERIVATIVES AS SEROTONERGIC PSYCHEDELIC AGENTS FOR THE TREATMENT OF CNS DISORDERS

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU718434B2 (en) 1995-02-17 2000-04-13 Mitsubishi-Tokyo Pharmaceuticals, Inc. Process for producing indoline compounds and intermediates for the production of the same

Also Published As

Publication number Publication date
US20030232988A1 (en) 2003-12-18
US6841685B2 (en) 2005-01-11
WO2001094310A1 (en) 2001-12-13

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