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AU2001268686A1 - Low oxygen affinity mutant hemoglobins - Google Patents

Low oxygen affinity mutant hemoglobins

Info

Publication number
AU2001268686A1
AU2001268686A1 AU2001268686A AU6868601A AU2001268686A1 AU 2001268686 A1 AU2001268686 A1 AU 2001268686A1 AU 2001268686 A AU2001268686 A AU 2001268686A AU 6868601 A AU6868601 A AU 6868601A AU 2001268686 A1 AU2001268686 A1 AU 2001268686A1
Authority
AU
Australia
Prior art keywords
low oxygen
oxygen affinity
affinity mutant
mutant hemoglobins
hemoglobins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001268686A
Inventor
Tsuei-Yun Fang
Chien Ho
Tong-Jian Shen
Ching-Hsuan Tsai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Carnegie Mellon University
Original Assignee
Carnegie Mellon University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carnegie Mellon University filed Critical Carnegie Mellon University
Publication of AU2001268686A1 publication Critical patent/AU2001268686A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795Porphyrin- or corrin-ring-containing peptides
    • C07K14/805Haemoglobins; Myoglobins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2001268686A 2000-06-21 2001-06-21 Low oxygen affinity mutant hemoglobins Abandoned AU2001268686A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09598218 2000-06-21
US09/598,218 US6486123B1 (en) 2000-06-21 2000-06-21 Low oxygen affinity mutant hemoglobins
PCT/US2001/020006 WO2001098356A1 (en) 2000-06-21 2001-06-21 Low oxygen affinity mutant hemoglobins

Publications (1)

Publication Number Publication Date
AU2001268686A1 true AU2001268686A1 (en) 2002-01-02

Family

ID=24394697

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001268686A Abandoned AU2001268686A1 (en) 2000-06-21 2001-06-21 Low oxygen affinity mutant hemoglobins

Country Status (7)

Country Link
US (4) US6486123B1 (en)
EP (1) EP1294767A1 (en)
JP (1) JP2004500871A (en)
CN (1) CN1262566C (en)
AU (1) AU2001268686A1 (en)
CA (1) CA2414028A1 (en)
WO (1) WO2001098356A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070066548A1 (en) * 2003-03-14 2007-03-22 Albert Einstein College Of Medicine Of Yeshiva University Globin variant gene methods and compositions
US20040193096A1 (en) * 2003-03-25 2004-09-30 Cooper William Isaac Conceptus chamber
US6979999B2 (en) * 2004-02-26 2005-12-27 General Electric Company Method and system of mapping oxygen concentration across a region-of-interest
EP2058398A1 (en) 2007-11-09 2009-05-13 Nipro Corporation Production of recombinant human hemoglobin using pichia yeast
WO2015100235A1 (en) 2013-12-27 2015-07-02 Virginia Commonwealth University Allosteric hemoglobin modifiers with nitric oxide releasing moiety
JP2016027326A (en) * 2014-06-26 2016-02-18 アークレイ株式会社 Measuring method, measuring apparatus and eluent
US9713602B1 (en) * 2016-03-15 2017-07-25 National Sun Yat-Sen University Method for facilitating the oxygen release of hemoglobin-based blood substitutes
GB201704006D0 (en) 2017-03-13 2017-04-26 Univ Essex Modified globin proteins
JP7387597B2 (en) 2017-07-18 2023-11-28 ヴァーテック・バイオ・インコーポレイテッド Blood substitute containing hemoglobin and production method
CN119192345A (en) * 2024-09-09 2024-12-27 江南大学 Hemoglobin mutants with improved stability and their applications

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1502858A (en) * 1920-12-09 1924-07-29 Strong Scott Mfg Company Air-heating means
GB8711614D0 (en) 1987-05-16 1987-06-24 Medical Res Council Proteins
US5753465A (en) 1994-08-30 1998-05-19 Carnegie Mellon University Unmodified recombinant human adult hemoglobin production
US5843888A (en) 1995-05-01 1998-12-01 Carnegie Mellon University Low oxygen affinity mutant hemoglobin

Also Published As

Publication number Publication date
CN1444603A (en) 2003-09-24
US6803212B2 (en) 2004-10-12
US20020151468A1 (en) 2002-10-17
CA2414028A1 (en) 2001-12-27
US6812328B2 (en) 2004-11-02
WO2001098356A1 (en) 2001-12-27
JP2004500871A (en) 2004-01-15
US20020151469A1 (en) 2002-10-17
US6486123B1 (en) 2002-11-26
EP1294767A1 (en) 2003-03-26
US6808898B2 (en) 2004-10-26
CN1262566C (en) 2006-07-05
US20020193293A1 (en) 2002-12-19

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