AU2001268007A1 - Novel cytotoxic compounds and their use - Google Patents
Novel cytotoxic compounds and their useInfo
- Publication number
- AU2001268007A1 AU2001268007A1 AU2001268007A AU6800701A AU2001268007A1 AU 2001268007 A1 AU2001268007 A1 AU 2001268007A1 AU 2001268007 A AU2001268007 A AU 2001268007A AU 6800701 A AU6800701 A AU 6800701A AU 2001268007 A1 AU2001268007 A1 AU 2001268007A1
- Authority
- AU
- Australia
- Prior art keywords
- cysteamine
- phospho
- aminoethanol
- phosphate
- linolenoyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 231100000433 cytotoxic Toxicity 0.000 title 1
- 230000001472 cytotoxic effect Effects 0.000 title 1
- 150000001408 amides Chemical class 0.000 abstract 2
- OSXDKPMVQBAQNA-UHFFFAOYSA-N 2-(docosa-2,4,6,8,10,12-hexaenoyloxyamino)ethoxy-oxido-oxophosphanium Chemical compound C(C=CC=CC=CC=CC=CC=CCCCCCCCCC)(=O)ONCCOP(=O)=O OSXDKPMVQBAQNA-UHFFFAOYSA-N 0.000 abstract 1
- JAVWBHAJWQRZDD-UHFFFAOYSA-N 2-(icosa-2,4,6,8,10-pentaenoyloxyamino)ethoxy-oxido-oxophosphanium Chemical compound C(C=CC=CC=CC=CC=CCCCCCCCCC)(=O)ONCCOP(=O)=O JAVWBHAJWQRZDD-UHFFFAOYSA-N 0.000 abstract 1
- DXXJDTSNRNNWHQ-DOFZRALJSA-N 2-[[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl]oxyamino]ethoxy-oxido-oxophosphanium Chemical compound C(CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC)(=O)ONCCOP(=O)=O DXXJDTSNRNNWHQ-DOFZRALJSA-N 0.000 abstract 1
- LZJUKIQAXWBZFI-QNEBEIHSSA-N 2-[[(6Z,9Z,12Z)-octadeca-6,9,12-trienoyl]oxyamino]ethoxy-oxido-oxophosphanium Chemical compound C(CCCC\C=C/C\C=C/C\C=C/CCCCC)(=O)ONCCOP(=O)=O LZJUKIQAXWBZFI-QNEBEIHSSA-N 0.000 abstract 1
- JUMALYVMTSKVLY-PDBXOOCHSA-N 2-[[(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl]oxyamino]ethoxy-oxido-oxophosphanium Chemical compound C(CCCCCCC\C=C/C\C=C/C\C=C/CC)(=O)ONCCOP(=O)=O JUMALYVMTSKVLY-PDBXOOCHSA-N 0.000 abstract 1
- SHGAZHPCJJPHSC-NUEINMDLSA-N Isotretinoin Chemical compound OC(=O)C=C(C)/C=C/C=C(C)C=CC1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-NUEINMDLSA-N 0.000 abstract 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- RZPNFYXFSHGGBE-UHFFFAOYSA-N cysteamine S-phosphate Chemical compound NCCSP(O)(O)=O RZPNFYXFSHGGBE-UHFFFAOYSA-N 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 229960005280 isotretinoin Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- DCWXELXMIBXGTH-QMMMGPOBSA-N phosphonotyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(OP(O)(O)=O)C=C1 DCWXELXMIBXGTH-QMMMGPOBSA-N 0.000 abstract 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 abstract 1
- 229930002330 retinoic acid Natural products 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
- C07F9/165—Esters of thiophosphoric acids
- C07F9/1651—Esters of thiophosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21781000P | 2000-07-12 | 2000-07-12 | |
| SE0002629A SE0002629D0 (sv) | 2000-07-12 | 2000-07-12 | Novel compounds and their use |
| US60217810 | 2000-07-12 | ||
| SE0002629 | 2000-07-12 | ||
| PCT/SE2001/001559 WO2002004467A1 (en) | 2000-07-12 | 2001-07-05 | Novel cytotoxic compounds and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001268007A1 true AU2001268007A1 (en) | 2002-01-21 |
Family
ID=26655180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001268007A Abandoned AU2001268007A1 (en) | 2000-07-12 | 2001-07-05 | Novel cytotoxic compounds and their use |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6699851B2 (es) |
| EP (1) | EP1299400B1 (es) |
| AT (1) | ATE339429T1 (es) |
| AU (1) | AU2001268007A1 (es) |
| DE (1) | DE60123058T2 (es) |
| ES (1) | ES2272490T3 (es) |
| WO (1) | WO2002004467A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110300190A1 (en) * | 2010-06-08 | 2011-12-08 | Krisani Biosciences (P) Ltd | Compound, composition and uses thereof |
| WO2014045293A1 (en) * | 2012-09-24 | 2014-03-27 | Krisani Bioscience (P) Ltd. | Fatty acid amides with a cysteamine or an acetylated cysteamine group and uses thereof |
| AU2020225354B2 (en) * | 2019-02-21 | 2025-03-06 | Centre National De La Recherche Scientifique | Structured molecular vectors for anti-inflammatory compounds and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9802162D0 (sv) * | 1998-06-17 | 1998-06-17 | Nomet Management Services Bv | Immunostimulating composition |
| SE9900941D0 (sv) * | 1998-12-23 | 1999-03-16 | Nomet Management Serv Bv | Novel retinoic acid derivatives and their use |
| JP4643009B2 (ja) * | 1999-03-11 | 2011-03-02 | アーデニア・インベストメンツ・リミテッド | 癌治療のための新規化合物 |
-
2001
- 2001-07-05 ES ES01945899T patent/ES2272490T3/es not_active Expired - Lifetime
- 2001-07-05 AU AU2001268007A patent/AU2001268007A1/en not_active Abandoned
- 2001-07-05 US US10/332,745 patent/US6699851B2/en not_active Expired - Lifetime
- 2001-07-05 DE DE60123058T patent/DE60123058T2/de not_active Expired - Lifetime
- 2001-07-05 WO PCT/SE2001/001559 patent/WO2002004467A1/en not_active Ceased
- 2001-07-05 AT AT01945899T patent/ATE339429T1/de active
- 2001-07-05 EP EP01945899A patent/EP1299400B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2272490T3 (es) | 2007-05-01 |
| US6699851B2 (en) | 2004-03-02 |
| DE60123058D1 (de) | 2006-10-26 |
| WO2002004467A1 (en) | 2002-01-17 |
| ATE339429T1 (de) | 2006-10-15 |
| US20030171338A1 (en) | 2003-09-11 |
| EP1299400B1 (en) | 2006-09-13 |
| EP1299400A1 (en) | 2003-04-09 |
| DE60123058T2 (de) | 2007-04-05 |
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