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AU2001264317A1 - Preparations for oligonucleotide transfer - Google Patents

Preparations for oligonucleotide transfer

Info

Publication number
AU2001264317A1
AU2001264317A1 AU2001264317A AU6431701A AU2001264317A1 AU 2001264317 A1 AU2001264317 A1 AU 2001264317A1 AU 2001264317 A AU2001264317 A AU 2001264317A AU 6431701 A AU6431701 A AU 6431701A AU 2001264317 A1 AU2001264317 A1 AU 2001264317A1
Authority
AU
Australia
Prior art keywords
preparations
oligonucleotide transfer
oligonucleotide
transfer
collagen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001264317A
Inventor
Masayasu Furuse
Hiroshi Itoh
Shunichiro Kubota
Shunji Nagahara
Takahiro Ochiya
Akihiko Sano
Masaaki Terada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koken Co Ltd
Sumitomo Pharma Co Ltd
Original Assignee
Koken Co Ltd
Sumitomo Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koken Co Ltd, Sumitomo Pharmaceuticals Co Ltd filed Critical Koken Co Ltd
Publication of AU2001264317A1 publication Critical patent/AU2001264317A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/7105Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2063Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Preparations for transferring efficiently oligonucleotides necessary in antisense therapy or the like into animal cells so as to be useful in treatment for various diseases, which comprises a collagen as an essential component are provided.
AU2001264317A 2000-06-20 2001-06-19 Preparations for oligonucleotide transfer Abandoned AU2001264317A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000184502 2000-06-20
JP2000-184502 2000-06-20
PCT/JP2001/005195 WO2001097857A1 (en) 2000-06-20 2001-06-19 Preparations for oligonucleotide transfer

Publications (1)

Publication Number Publication Date
AU2001264317A1 true AU2001264317A1 (en) 2002-01-02

Family

ID=18684937

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001264317A Abandoned AU2001264317A1 (en) 2000-06-20 2001-06-19 Preparations for oligonucleotide transfer

Country Status (10)

Country Link
US (3) US20040052840A1 (en)
EP (1) EP1295611B1 (en)
JP (1) JP5118285B2 (en)
AT (1) ATE478688T1 (en)
AU (1) AU2001264317A1 (en)
DE (1) DE60142899D1 (en)
DK (1) DK1295611T3 (en)
ES (1) ES2349137T3 (en)
PT (1) PT1295611E (en)
WO (1) WO2001097857A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW586934B (en) * 1997-05-19 2004-05-11 Sumitomo Pharma Immunopotentiating composition
EP1295611B1 (en) * 2000-06-20 2010-08-25 Dainippon Sumitomo Pharma Co., Ltd. Oligonucleotide-transferring preparations
EP1407787B1 (en) * 2001-06-20 2009-04-29 Dainippon Sumitomo Pharma Co., Ltd. Method of promoting nucleic acid transfer
US20100104631A1 (en) * 2001-08-13 2010-04-29 Lipella Pharmaceuticals Inc. Method of treatment for bladder dysfunction
EP1550463A4 (en) * 2002-09-20 2006-12-27 Dainippon Sumitomo Pharma Co Preparation for facilitating site-specific gene conversion and preparation for gene therapy
US20080318319A1 (en) * 2003-12-19 2008-12-25 Yoshiko Minakuchi Novel Method of Nucleic Acid Transfer
US20090062184A1 (en) * 2005-03-24 2009-03-05 Dainippon Sumitomo Pharma Co., Ltd. Fine particulate preparation comprising complex of nucleic acid molecule and collagen
US7838502B2 (en) * 2005-05-06 2010-11-23 University Of Massachusetts Medical School Compositions and methods to modulate H. influenzae pathogenesis
ES2405357T3 (en) * 2005-05-25 2013-05-30 Cellmid Limited Pharmaceutical composition for occlusive vasculopathy.
KR100777249B1 (en) * 2006-02-14 2007-11-28 (주)바이오니아 Dry oligonucleotide composition and preparation method thereof
WO2010078403A2 (en) * 2008-12-30 2010-07-08 Lipella Pharmaceuticals Inc. Methods and compositions for diagnosing urological disorders
FR3066115B1 (en) 2017-05-10 2019-06-28 Universite de Bordeaux COMPRESSES OF NUCLEIC ACID VECTORS

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5115094B2 (en) * 1972-11-01 1976-05-14
US5069936A (en) * 1987-06-25 1991-12-03 Yen Richard C K Manufacturing protein microspheres
US5078997A (en) * 1988-07-13 1992-01-07 Cetus Corporation Pharmaceutical composition for interleukin-2 containing physiologically compatible stabilizers
US5098890A (en) * 1988-11-07 1992-03-24 Temple University-Of The Commonwealth System Of Higher Education Antisence oligonucleotides to c-myb proto-oncogene and uses thereof
US5936035A (en) * 1988-11-21 1999-08-10 Cohesion Technologies, Inc. Biocompatible adhesive compositions
US5614587A (en) * 1988-11-21 1997-03-25 Collagen Corporation Collagen-based bioadhesive compositions
JP3187410B2 (en) * 1989-08-10 2001-07-11 住友製薬株式会社 Sustained release formulation for intracerebral administration
US5542935A (en) * 1989-12-22 1996-08-06 Imarx Pharmaceutical Corp. Therapeutic delivery systems related applications
US5264618A (en) * 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
FR2694895B1 (en) * 1992-08-20 1994-11-10 Coletica Process for the production of emulsion microparticles by modification of the chemical composition of the dispersed phase after emulsification.
US5646042A (en) * 1992-08-26 1997-07-08 Ribozyme Pharmaceuticals, Inc. C-myb targeted ribozymes
ATE182336T1 (en) * 1993-05-28 1999-08-15 Chiron Corp PEPTIDE INHIBITORS OF UROKINASE RECEPTOR ACTIVITY
HUT74509A (en) * 1993-09-09 1997-01-28 Schering Ag Active principles and gas containing microparticles, their use for realising active principles in ultrasonically controlled manner, and process for preparing them
CA2140053C (en) * 1994-02-09 2000-04-04 Joel S. Rosenblatt Collagen-based injectable drug delivery system and its use
US5942496A (en) * 1994-02-18 1999-08-24 The Regent Of The University Of Michigan Methods and compositions for multiple gene transfer into bone cells
US5583034A (en) * 1994-02-22 1996-12-10 La Jolla Institute For Allergy And Immunology Enhancement of adoptosis using antisense oligonucleotides
US5844107A (en) * 1994-03-23 1998-12-01 Case Western Reserve University Compacted nucleic acids and their delivery to cells
US5563255A (en) * 1994-05-31 1996-10-08 Isis Pharmaceuticals, Inc. Antisense oligonucleotide modulation of raf gene expression
JPH11505505A (en) * 1994-06-27 1999-05-21 ザ・ジョンズ・ホプキンス・ユニバーシティー Targeted gene delivery system
JP3867160B2 (en) * 1995-07-03 2007-01-10 大日本住友製薬株式会社 Gene preparation
US6998268B2 (en) * 1995-07-03 2006-02-14 Dainippon Sumitomo Pharma Co. Ltd. Gene preparations
CN1230205C (en) * 1995-07-03 2005-12-07 株式会社高研 gene preparation
CN1209068A (en) * 1995-10-23 1999-02-24 海欧制药澳大利亚有限公司 Hyaluronic acid as DNA carrier for gene therapy and VEGF antisense DNA to treat abnormal retinal vascularization
PT876165E (en) * 1995-12-18 2006-10-31 Angiotech Biomaterials Corp COMPOSITIONS OF RETICULATED POLYMERS AND PROCESSES FOR THEIR USE
EP0904373A1 (en) * 1996-03-14 1999-03-31 The Immune Response Corporation Targeted delivery of genes encoding interferon
US6133437A (en) * 1997-02-13 2000-10-17 Apoptogen, Inc. Modulation of IAPs for the treatment of proliferative diseases
US5874006A (en) * 1996-10-31 1999-02-23 Matrix Pharmaceutical, Inc. Aseptic collagen concentration process
US6042820A (en) * 1996-12-20 2000-03-28 Connaught Laboratories Limited Biodegradable copolymer containing α-hydroxy acid and α-amino acid units
US6218112B1 (en) * 1996-12-23 2001-04-17 Cobra Therapeutics Limited Optimization of gene delivery and gene delivery system
EP0968223B1 (en) * 1997-01-08 2016-12-21 Sigma-Aldrich Co. LLC Bioconjugation of macromolecules
US6524613B1 (en) * 1997-04-30 2003-02-25 Regents Of The University Of Minnesota Hepatocellular chimeraplasty
AU2868099A (en) * 1998-02-13 1999-08-30 Selective Genetics, Inc. Concurrent flow mixing methods and apparatuses for the preparation of gene therapy vectors and compositions prepared thereby
NZ508785A (en) * 1998-05-22 2003-10-31 Sumitomo Pharma Stable gene formulations
EP1274410A2 (en) * 2000-03-31 2003-01-15 Trustees Of Boston University Use of locally applied dna fragments
EP1295611B1 (en) * 2000-06-20 2010-08-25 Dainippon Sumitomo Pharma Co., Ltd. Oligonucleotide-transferring preparations
JP2002325572A (en) * 2000-12-25 2002-11-12 Univ Osaka How to introduce foreign substances
EP1407787B1 (en) * 2001-06-20 2009-04-29 Dainippon Sumitomo Pharma Co., Ltd. Method of promoting nucleic acid transfer
US7148342B2 (en) * 2002-07-24 2006-12-12 The Trustees Of The University Of Pennyslvania Compositions and methods for sirna inhibition of angiogenesis
WO2004022075A1 (en) * 2002-09-04 2004-03-18 Novartis Ag Treatment of neurological disorders by dsrna adminitration
EP1550463A4 (en) * 2002-09-20 2006-12-27 Dainippon Sumitomo Pharma Co Preparation for facilitating site-specific gene conversion and preparation for gene therapy
CA2504926C (en) * 2002-11-01 2014-01-14 The Trustees Of The University Of Pennsylvania Compositions and methods for sirna inhibition of hif-1 alpha
CA2513623A1 (en) * 2003-01-16 2004-08-05 The Trustees Of The University Of Pennsylvania Compositions and methods for sirna inhibition of icam-1
US8227434B1 (en) * 2003-11-04 2012-07-24 H. Lee Moffitt Cancer Center & Research Institute, Inc. Materials and methods for treating oncological disorders
ES2523147T3 (en) * 2004-02-26 2014-11-21 Baylor Research Institute Compositions and methods for the systemic treatment of arthritis
PL1799269T3 (en) * 2004-09-28 2017-01-31 Quark Pharmaceuticals, Inc. Oligoribonucleotides and methods of use thereof for treatment of alopecia, acute renal failure and other diseases
US8187823B2 (en) * 2004-10-22 2012-05-29 UNIVERSITé LAVAL Modulation of neuroglia-derived BDNF in the treatment and prevention of pain
US7585848B2 (en) * 2005-01-11 2009-09-08 Rush University Medical Center Methods and compositions for treating, inhibiting and reversing disorders of the intervertebral disc
WO2007082899A1 (en) * 2006-01-17 2007-07-26 Vib Vzw Inhibitors of prolyl-hydroxylase 1 for the treatment of skeletal muscle degeneration
US8106024B2 (en) * 2006-06-16 2012-01-31 Taisho Pharmaceutical Co., Ltd. Method of treating cancer with an RPN2 gene expression inhibitor
CN101490253A (en) * 2006-07-21 2009-07-22 赛伦斯治疗公司 Methods for inhibiting protein kinase 3 expression
WO2008028085A2 (en) * 2006-08-30 2008-03-06 The Board Of Trustees Of The University Of Illinois Modulation of mlck-l expression and uses thereof
CA2665202A1 (en) * 2006-10-02 2008-04-10 Aprea Ab Compounds and methods
US7812002B2 (en) * 2007-03-21 2010-10-12 Quark Pharmaceuticals, Inc. Oligoribonucleotide inhibitors of NRF2 and methods of use thereof for treatment of cancer
CN102812126A (en) * 2009-12-04 2012-12-05 奥普科制药有限责任公司 Compositions And Methods For Inhibition Of VEGF

Also Published As

Publication number Publication date
WO2001097857A1 (en) 2001-12-27
ATE478688T1 (en) 2010-09-15
ES2349137T3 (en) 2010-12-28
EP1295611B1 (en) 2010-08-25
DE60142899D1 (en) 2010-10-07
US20090258933A1 (en) 2009-10-15
JP5118285B2 (en) 2013-01-16
DK1295611T3 (en) 2010-10-04
US20040052840A1 (en) 2004-03-18
EP1295611A4 (en) 2009-07-08
US20110028535A1 (en) 2011-02-03
PT1295611E (en) 2010-09-14
EP1295611A1 (en) 2003-03-26

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