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AU2001263059A1 - Method of regulating biological activity of pituitary tumor transforming gene (pttg)1 using pttg2 - Google Patents

Method of regulating biological activity of pituitary tumor transforming gene (pttg)1 using pttg2

Info

Publication number
AU2001263059A1
AU2001263059A1 AU2001263059A AU6305901A AU2001263059A1 AU 2001263059 A1 AU2001263059 A1 AU 2001263059A1 AU 2001263059 A AU2001263059 A AU 2001263059A AU 6305901 A AU6305901 A AU 6305901A AU 2001263059 A1 AU2001263059 A1 AU 2001263059A1
Authority
AU
Australia
Prior art keywords
pttg2
pttg
biological activity
pituitary tumor
transforming gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001263059A
Inventor
Anthony P. Heaney
Shlomo Melmed
Toni Rita Prezant
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cedars Sinai Medical Center
Original Assignee
Cedars Sinai Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/569,956 external-priority patent/US6894031B1/en
Priority claimed from US09/730,469 external-priority patent/US20030018001A1/en
Application filed by Cedars Sinai Medical Center filed Critical Cedars Sinai Medical Center
Priority claimed from PCT/US2001/015255 external-priority patent/WO2001087039A2/en
Publication of AU2001263059A1 publication Critical patent/AU2001263059A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
AU2001263059A 2000-05-12 2001-05-12 Method of regulating biological activity of pituitary tumor transforming gene (pttg)1 using pttg2 Abandoned AU2001263059A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US09/569,956 US6894031B1 (en) 1996-11-21 2000-05-12 Pituitary tumor transforming gene (PTTG) carboxy-terminal peptides and methods of use thereof to inhibit neoplastic cellular proliferation and/or transformation
US09569956 2000-05-12
US68791100A 2000-10-13 2000-10-13
US09687911 2000-10-13
US09/730,469 US20030018001A1 (en) 1996-11-21 2000-12-04 Methods of using pituitary tumor transforming gene (PTTG) carboxy-terminal peptides to inhibit neoplastic cellular proliferation and/or transformation of breast and ovarian cells
US09730469 2000-12-04
US09777422 2001-02-05
US09/777,422 US20020147162A1 (en) 1996-11-21 2001-02-05 Methods of modulating angiogenesis by regulating the expression of pituitary tumor transforming gene (PTTG)
PCT/US2001/015255 WO2001087039A2 (en) 2000-05-12 2001-05-12 Treatment of neoplasia / transformation using pituitary tumor transforming gene 2

Publications (1)

Publication Number Publication Date
AU2001263059A1 true AU2001263059A1 (en) 2001-11-26

Family

ID=27504884

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001263059A Abandoned AU2001263059A1 (en) 2000-05-12 2001-05-12 Method of regulating biological activity of pituitary tumor transforming gene (pttg)1 using pttg2
AU2001261443A Abandoned AU2001261443A1 (en) 2000-05-12 2001-05-12 Pituitary tumor transforming gene (pttg) carboxy-terminal peptides and methods of use thereof to inhibit neoplastic cellular proliferation and/or transformation

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2001261443A Abandoned AU2001261443A1 (en) 2000-05-12 2001-05-12 Pituitary tumor transforming gene (pttg) carboxy-terminal peptides and methods of use thereof to inhibit neoplastic cellular proliferation and/or transformation

Country Status (5)

Country Link
US (1) US20020147162A1 (en)
EP (1) EP1280905A2 (en)
JP (2) JP2003535612A (en)
AU (2) AU2001263059A1 (en)
WO (1) WO2001087934A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10200410A1 (en) * 2002-01-08 2003-07-24 Marc Roller New antisense oligonucleotide, useful for treatment of tumors, inhibits translation of mRNA from the pituitary-tumor transforming gene-1
KR100627377B1 (en) 2005-03-04 2006-09-25 한국생명공학연구원 Gene therapy of cancer using a small interfering RNA and a vector expressing the same, which may block the synthesis of pituitary tumor-transforming gene 1 protein

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002511734A (en) * 1996-11-21 2002-04-16 シーダーズ―サイナイ・メディカル・センター Pituitary-tumor-transforming genes and related products

Also Published As

Publication number Publication date
EP1280905A2 (en) 2003-02-05
WO2001087934A3 (en) 2002-05-30
JP2003535612A (en) 2003-12-02
WO2001087934A2 (en) 2001-11-22
AU2001261443A1 (en) 2001-11-26
JP2004526403A (en) 2004-09-02
US20020147162A1 (en) 2002-10-10

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