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AU2001262113A1 - Indoles for treating diseases that can be treated using thyroid hormones - Google Patents

Indoles for treating diseases that can be treated using thyroid hormones

Info

Publication number
AU2001262113A1
AU2001262113A1 AU2001262113A AU6211301A AU2001262113A1 AU 2001262113 A1 AU2001262113 A1 AU 2001262113A1 AU 2001262113 A AU2001262113 A AU 2001262113A AU 6211301 A AU6211301 A AU 6211301A AU 2001262113 A1 AU2001262113 A1 AU 2001262113A1
Authority
AU
Australia
Prior art keywords
indoles
treated
treating diseases
thyroid hormones
thyroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001262113A
Inventor
Heiner Apeler
Hilmar Bischoff
Christiane Faeste
Helmut Haning
Markus Hauswald
Willi Jonghaus
Axel Kretschmer
Ulrich Muller
Josef Pernerstorfer
Peter Reinemer
Carsten Schmeck
Delf Schmidt
Gunter Schmidt
Verena Vohringer
Michael Woltering
Martin Zoche
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10065434A external-priority patent/DE10065434A1/en
Application filed by Bayer AG filed Critical Bayer AG
Publication of AU2001262113A1 publication Critical patent/AU2001262113A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001262113A 2000-03-23 2001-03-19 Indoles for treating diseases that can be treated using thyroid hormones Abandoned AU2001262113A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
DE10014370 2000-03-23
DE10014370 2000-03-23
DE10038975 2000-08-10
DE10038975 2000-08-10
DE10065434A DE10065434A1 (en) 2000-03-23 2000-12-27 indoles
DE10065434 2000-12-27
PCT/EP2001/003144 WO2001070687A1 (en) 2000-03-23 2001-03-19 Indoles for treating diseases that can be treated using thyroid hormones

Publications (1)

Publication Number Publication Date
AU2001262113A1 true AU2001262113A1 (en) 2001-10-03

Family

ID=27213746

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001262113A Abandoned AU2001262113A1 (en) 2000-03-23 2001-03-19 Indoles for treating diseases that can be treated using thyroid hormones

Country Status (5)

Country Link
EP (1) EP1268422A1 (en)
AU (1) AU2001262113A1 (en)
CA (1) CA2403806A1 (en)
HN (1) HN2001000059A (en)
WO (1) WO2001070687A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2433100A1 (en) 2000-12-27 2002-07-04 Helmut Haning Indole derivatives as ligands of thyroid receptors
IL157031A0 (en) 2001-02-08 2004-02-08 Karobio Ab Thyroid receptor ligands
DE60214080T2 (en) * 2001-05-31 2007-01-04 Pfizer Products Inc., Groton Medical use of thyromimetic hair loss compounds and compositions
ES2253495T3 (en) 2001-09-26 2006-06-01 Pfizer Products Inc. INDO CARBOXILIC ACIDS AS LIGHTING OF THYROID RECEPTORS.
US20030187026A1 (en) 2001-12-13 2003-10-02 Qun Li Kinase inhibitors
CA2473162A1 (en) * 2002-01-30 2003-08-07 Kissei Pharmaceutical Co., Ltd. Novel thyroid hormone receptor ligand, medicinal compositions containing the same and use thereof
GB0219022D0 (en) * 2002-08-15 2002-09-25 Karobio Ab Novel thyromimetic compounds
TW200504021A (en) 2003-01-24 2005-02-01 Bristol Myers Squibb Co Substituted anilide ligands for the thyroid receptor
AU2004235923B2 (en) 2003-05-09 2008-01-24 F. Hoffmann-La Roche Ag Methyl indoles and methyl pyrrolopyridines as alpha-1 adrenergic agonists
GB0513692D0 (en) * 2005-07-04 2005-08-10 Karobio Ab Novel pharmaceutical compositions
EP2036887A1 (en) 2006-06-28 2009-03-18 Sanwa Kagaku Kenkyusho Co., Ltd Novel 6-5 bicycic heterocyclic derivative and medical use thereof
ES2395682T3 (en) 2007-08-20 2013-02-14 Symrise Ag Oxalic acid derivatives and their use as physiological refreshing active ingredients
CN104193699B (en) * 2014-08-14 2016-05-25 嘉兴特科罗生物科技有限公司 A kind of micromolecular compound and synthetic method and application
AU2021306314A1 (en) * 2020-07-10 2023-02-09 Aligos Therapeutics, Inc. Modulators of THR-β and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8501372D0 (en) * 1985-01-18 1985-02-20 Smith Kline French Lab Chemical compounds
JPH07145147A (en) * 1993-11-26 1995-06-06 Yamanouchi Pharmaceut Co Ltd Benzoic acid derivative or its salt
GB9401436D0 (en) * 1994-01-26 1994-03-23 Wellcome Found Therapeutic heterocyclic compounds
PT1033364E (en) * 1999-03-01 2005-07-29 Pfizer Prod Inc CYANO WITH OXAMIC ACIDS AND DERIVED AS TIROIDE RECEPTOR LIGANDS
CZ20013117A3 (en) * 1999-03-01 2002-06-12 Pfizer Products Inc. Oxamic acids and derivatives as thyroid receptor ligands

Also Published As

Publication number Publication date
CA2403806A1 (en) 2002-09-20
EP1268422A1 (en) 2003-01-02
HN2001000059A (en) 2001-07-24
WO2001070687A1 (en) 2001-09-27

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