[go: up one dir, main page]

AU2001259511A1 - Novel anti-infectives - Google Patents

Novel anti-infectives

Info

Publication number
AU2001259511A1
AU2001259511A1 AU2001259511A AU5951101A AU2001259511A1 AU 2001259511 A1 AU2001259511 A1 AU 2001259511A1 AU 2001259511 A AU2001259511 A AU 2001259511A AU 5951101 A AU5951101 A AU 5951101A AU 2001259511 A1 AU2001259511 A1 AU 2001259511A1
Authority
AU
Australia
Prior art keywords
infectives
novel anti
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001259511A
Inventor
Thomas Carr
Dashyant Dhanak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of AU2001259511A1 publication Critical patent/AU2001259511A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
AU2001259511A 2000-05-05 2001-05-04 Novel anti-infectives Abandoned AU2001259511A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20194500P 2000-05-05 2000-05-05
US60201945 2000-05-05
PCT/US2001/014525 WO2001085720A1 (en) 2000-05-05 2001-05-04 Novel anti-infectives

Publications (1)

Publication Number Publication Date
AU2001259511A1 true AU2001259511A1 (en) 2001-11-20

Family

ID=22747931

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001259511A Abandoned AU2001259511A1 (en) 2000-05-05 2001-05-04 Novel anti-infectives

Country Status (5)

Country Link
US (1) US6713502B2 (en)
EP (1) EP1278743A4 (en)
JP (1) JP2003532726A (en)
AU (1) AU2001259511A1 (en)
WO (1) WO2001085720A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005511572A (en) * 2001-11-02 2005-04-28 グラクソ グループ リミテッド Acyl dihydropyrrole derivatives as HCV inhibitors
GB0211418D0 (en) * 2002-05-17 2002-06-26 Glaxo Group Ltd Compounds
US6930106B2 (en) * 2002-07-01 2005-08-16 Pharmacia & Upjohn Company Inhibitors of HCV NS5B polymerase
GB0216985D0 (en) * 2002-07-22 2002-08-28 Glaxo Group Ltd Compounds
WO2004037818A1 (en) * 2002-10-24 2004-05-06 Glaxo Group Limited 1-acyl-pyrrolidine derivatives for the treatment of viral infections
AP2005003319A0 (en) 2002-11-19 2005-06-30 Achillion Pharmaceitucals Inc Substituted aryl thioureas and related compounds; inhibitors of viral replication
WO2004060889A1 (en) * 2003-01-07 2004-07-22 Glaxo Group Limited 5-thiazole substituted 2-pyrrolidine-carboxylic acids
GB0304494D0 (en) * 2003-02-27 2003-04-02 Glaxo Group Ltd Compounds
US7034051B2 (en) * 2003-08-28 2006-04-25 Adolor Corporation Fused bicyclic carboxamide derivatives and methods of their use
PL1718608T3 (en) 2004-02-20 2013-11-29 Boehringer Ingelheim Int Viral polymerase inhibitors
US7741347B2 (en) * 2007-05-17 2010-06-22 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
KR20100123717A (en) * 2008-02-12 2010-11-24 브리스톨-마이어스 스큅 컴퍼니 Heterocyclic derivatives as hepatitis c virus inhibitors
MA32975B1 (en) * 2008-12-22 2012-01-02 Chemocentryx Inc ANTAGONISTS OF C5AR
CN102812003B (en) 2009-12-18 2015-01-21 欧洲筛选有限公司 Pyrrolidine Or Thiazolidine Carboxylic Acid Derivatives, Pharmaceutical Composition And Methods For Use In Treating Metabolic Disordersas As Agonists Of G- Protein Coupled Receptor 43 (GPR43)
SI2585064T1 (en) 2010-06-24 2017-08-31 Chemocentryx, Inc. C5ar antagonists
JP6854126B2 (en) 2013-11-27 2021-04-07 エピックス セラピューティクス Compounds, pharmaceutical compositions, and methods for use in the treatment of inflammatory diseases
CN113121415B (en) 2014-09-29 2025-09-02 凯莫森特里克斯股份有限公司 Methods and intermediates for preparing C5aR antagonists
CN108601790A (en) 2016-01-14 2018-09-28 凯莫森特里克斯股份有限公司 The therapy of C3 glomerulopathies

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997005108A1 (en) * 1995-07-26 1997-02-13 Mitsubishi Chemical Corporation Penicillaminamide derivatives
US6323180B1 (en) * 1998-08-10 2001-11-27 Boehringer Ingelheim (Canada) Ltd Hepatitis C inhibitor tri-peptides

Also Published As

Publication number Publication date
EP1278743A1 (en) 2003-01-29
US6713502B2 (en) 2004-03-30
EP1278743A4 (en) 2003-05-14
US20040010030A1 (en) 2004-01-15
WO2001085720A1 (en) 2001-11-15
JP2003532726A (en) 2003-11-05

Similar Documents

Publication Publication Date Title
AU2001261377A1 (en) Novel anti-infectives
AU2002365198A1 (en) Novel anti-infectives
AU2001262847A1 (en) Language-understanding
AU2001292739A1 (en) 1-oxorapamycins
AU2002211620A1 (en) Autoanastomosis
AU2001254546A1 (en) Aminopiperidines
AU2000267458A1 (en) Hypercomputer
AU2001239310A1 (en) Decahydro-isoquinolines
AU2001296577A1 (en) Chlorophyllases
AU2001258349A1 (en) Bisacylguanidine
AU2001279754A1 (en) Indoloquinazolinones
AU2001259511A1 (en) Novel anti-infectives
AU2002211128A1 (en) Step-bike
AU2001290931A1 (en) Ski-snowboard
AU2001281965A1 (en) Novel 6-phenylphenanthridines
AU2001285886A1 (en) 2-guanidino-4-aryl-quinazoline
AU2001293852A1 (en) Sulfonylguanidine
AU2001258924A1 (en) Microsatellite-aflp
AU2002226346A1 (en) 2-aryl-5-trifluoromethylpyridines
AU2001246864A1 (en) Hypotensors
AU2001291876A1 (en) Triazolo-epothilones
AU2002214354A1 (en) Neck-phone
AU2001226668A1 (en) Crankshaft-starter-generator
AU2001295713A1 (en) Blast-processing
AU2001262711A1 (en) Cytoprotectors