AU2001259506A1 - Optical system and method for optically analyzing light from a sample - Google Patents
Optical system and method for optically analyzing light from a sampleInfo
- Publication number
- AU2001259506A1 AU2001259506A1 AU2001259506A AU5950601A AU2001259506A1 AU 2001259506 A1 AU2001259506 A1 AU 2001259506A1 AU 2001259506 A AU2001259506 A AU 2001259506A AU 5950601 A AU5950601 A AU 5950601A AU 2001259506 A1 AU2001259506 A1 AU 2001259506A1
- Authority
- AU
- Australia
- Prior art keywords
- light
- lens
- detection device
- light detection
- optical element
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 230000003287 optical effect Effects 0.000 title claims description 265
- 238000000034 method Methods 0.000 title claims description 74
- 238000001514 detection method Methods 0.000 claims description 160
- 238000000926 separation method Methods 0.000 claims description 59
- 230000005284 excitation Effects 0.000 claims description 58
- 230000005540 biological transmission Effects 0.000 claims description 50
- 230000003595 spectral effect Effects 0.000 claims description 37
- 230000000903 blocking effect Effects 0.000 claims description 26
- 230000004075 alteration Effects 0.000 claims description 25
- 238000012937 correction Methods 0.000 claims description 19
- 238000001962 electrophoresis Methods 0.000 claims description 11
- 239000006117 anti-reflective coating Substances 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 5
- 239000011248 coating agent Substances 0.000 claims description 4
- 238000000576 coating method Methods 0.000 claims description 4
- 230000003667 anti-reflective effect Effects 0.000 claims 3
- 230000000694 effects Effects 0.000 description 15
- 241000282326 Felis catus Species 0.000 description 14
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- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 2
- 239000013307 optical fiber Substances 0.000 description 2
- 229910052724 xenon Inorganic materials 0.000 description 2
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 2
- YZCKVEUIGOORGS-OUBTZVSYSA-N Deuterium Chemical compound [2H] YZCKVEUIGOORGS-OUBTZVSYSA-N 0.000 description 1
- 238000001069 Raman spectroscopy Methods 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- XKRFYHLGVUSROY-UHFFFAOYSA-N argon Substances [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 1
- 229910052786 argon Inorganic materials 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 238000005251 capillar electrophoresis Methods 0.000 description 1
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- 238000010276 construction Methods 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 230000000593 degrading effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 229910052805 deuterium Inorganic materials 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 230000005670 electromagnetic radiation Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000005308 flint glass Substances 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
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- 229910052753 mercury Inorganic materials 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910052754 neon Inorganic materials 0.000 description 1
- GKAOGPIIYCISHV-UHFFFAOYSA-N neon atom Chemical compound [Ne] GKAOGPIIYCISHV-UHFFFAOYSA-N 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- 238000002966 oligonucleotide array Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
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- 229920000515 polycarbonate Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 229910052594 sapphire Inorganic materials 0.000 description 1
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- 125000006850 spacer group Chemical group 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 1
- 229910052721 tungsten Inorganic materials 0.000 description 1
- 239000010937 tungsten Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/0208—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using focussing or collimating elements, e.g. lenses or mirrors; performing aberration correction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/0229—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using masks, aperture plates, spatial light modulators or spatial filters, e.g. reflective filters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0262—Constructional arrangements for removing stray light
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0294—Multi-channel spectroscopy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/04—Slit arrangements slit adjustment
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/2803—Investigating the spectrum using photoelectric array detector
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/05—Flow-through cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
- G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
Landscapes
- Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Optical Measuring Cells (AREA)
- Spectrometry And Color Measurement (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/564,790 US6690467B1 (en) | 2000-05-05 | 2000-05-05 | Optical system and method for optically analyzing light from a sample |
| US09564790 | 2000-05-05 | ||
| PCT/US2001/014515 WO2001086240A2 (fr) | 2000-05-05 | 2001-05-04 | Systeme et procede optiques permettant d'analyser optiquement la lumiere provenant d'un echantillon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001259506A1 true AU2001259506A1 (en) | 2001-11-20 |
Family
ID=24255897
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001259506A Abandoned AU2001259506A1 (en) | 2000-05-05 | 2001-05-04 | Optical system and method for optically analyzing light from a sample |
Country Status (6)
| Country | Link |
|---|---|
| US (5) | US6690467B1 (fr) |
| EP (1) | EP1281053A2 (fr) |
| JP (1) | JP2003532887A (fr) |
| AU (1) | AU2001259506A1 (fr) |
| CA (1) | CA2408265A1 (fr) |
| WO (1) | WO2001086240A2 (fr) |
Families Citing this family (110)
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| US6970201B1 (en) * | 2000-09-15 | 2005-11-29 | Panavision, Inc. | Method and lens system for modifying the modulation transfer function of light for a camera |
| EP1412724B1 (fr) * | 2001-07-25 | 2016-03-23 | Life Technologies Corporation | Integration de temporisation dans des dispositifs de detection electrophoretique |
| EP1504248A1 (fr) * | 2002-05-10 | 2005-02-09 | Applera Corporation | Systeme d'imagerie permettant de reduire des regions d'image interstitielles et procede associe |
| JP2005532152A (ja) * | 2002-06-12 | 2005-10-27 | トラップテック， エルエルシー | 被包化活性粒子、ならびにその製造法および使用法 |
| US7061611B2 (en) * | 2002-12-31 | 2006-06-13 | Wavefront Research, Inc. | Refractive relay spectrometer |
| JP2004361239A (ja) * | 2003-06-04 | 2004-12-24 | Enplas Corp | マイクロ分析システム用光学系 |
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| CA2589996C (fr) * | 2004-12-13 | 2012-02-21 | Bayer Healthcare Llc | Systeme de spectroscopie de transmission utilise pour la determination d'analytes dans un fluide corporel |
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2000
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2001
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- 2001-05-04 EP EP01933042A patent/EP1281053A2/fr not_active Withdrawn
- 2001-05-04 CA CA002408265A patent/CA2408265A1/fr not_active Abandoned
- 2001-05-04 AU AU2001259506A patent/AU2001259506A1/en not_active Abandoned
- 2001-05-04 WO PCT/US2001/014515 patent/WO2001086240A2/fr not_active Ceased
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| US20050270527A1 (en) | 2005-12-08 |
| US7477381B2 (en) | 2009-01-13 |
| WO2001086240A3 (fr) | 2002-03-21 |
| EP1281053A2 (fr) | 2003-02-05 |
| JP2003532887A (ja) | 2003-11-05 |
| CA2408265A1 (fr) | 2001-11-15 |
| US20070127023A1 (en) | 2007-06-07 |
| US6927852B2 (en) | 2005-08-09 |
| US20040160603A1 (en) | 2004-08-19 |
| US7139074B2 (en) | 2006-11-21 |
| US20090116028A1 (en) | 2009-05-07 |
| WO2001086240A2 (fr) | 2001-11-15 |
| US6690467B1 (en) | 2004-02-10 |
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