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AU2001258860A1 - Process for the production of nitrogen compounds - Google Patents

Process for the production of nitrogen compounds

Info

Publication number
AU2001258860A1
AU2001258860A1 AU2001258860A AU5886001A AU2001258860A1 AU 2001258860 A1 AU2001258860 A1 AU 2001258860A1 AU 2001258860 A AU2001258860 A AU 2001258860A AU 5886001 A AU5886001 A AU 5886001A AU 2001258860 A1 AU2001258860 A1 AU 2001258860A1
Authority
AU
Australia
Prior art keywords
production
synthesis
nitrogen compounds
nitrogen
containing compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001258860A
Inventor
Takashi Emura
Tsuyoshi Haneishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of AU2001258860A1 publication Critical patent/AU2001258860A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30Isothioureas
    • C07C335/32Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/14Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/18Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/02Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of guanidine from cyanamide, calcium cyanamide or dicyandiamides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A synthesis method which comprises reacting NH group-containing compounds with thiocyanates, cyanamides, nitriles or esters in the presence of a silylating agent to synthesize the corresponding nitrogen-containing addition or substitution products. This method not only enables the direct and efficient synthesis of nitrogen-containing compounds including isothioureas, guanidines, amidines and amides, but it also has a wide range of applications and is suitable for large-scale synthesis.
AU2001258860A 2000-05-29 2001-05-29 Process for the production of nitrogen compounds Abandoned AU2001258860A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000-158525 2000-05-29
JP2000158525 2000-05-29
PCT/JP2001/004504 WO2001092207A1 (en) 2000-05-29 2001-05-29 Process for the production of nitrogen compounds

Publications (1)

Publication Number Publication Date
AU2001258860A1 true AU2001258860A1 (en) 2001-12-11

Family

ID=18662989

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001258860A Abandoned AU2001258860A1 (en) 2000-05-29 2001-05-29 Process for the production of nitrogen compounds

Country Status (8)

Country Link
US (4) US6803472B2 (en)
EP (1) EP1285909B1 (en)
JP (1) JP3836425B2 (en)
AT (1) ATE405543T1 (en)
AU (1) AU2001258860A1 (en)
DE (1) DE60135457D1 (en)
TW (1) TWI295293B (en)
WO (1) WO2001092207A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2323876T3 (en) 2001-04-18 2009-07-27 Euro-Celtique S.A. DERIVATIVES OF 1- (4-PIPERIDINIL) -1,3-DIHIDRO-2H-BENZOXAZOL-2-ONA AND RELATED COMPOUNDS AS ANALOGS OF NOCICEPTINE AND LIGANDS OF ENT1 FOR THE TREATMENT OF PAIN.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US511975A (en) * 1894-01-02 Mary jane sullivan
DE2020155A1 (en) * 1970-04-24 1971-11-04 Ishihara Sangyo Kaisha Germicidal amidine derivs
FR2246545B1 (en) 1973-10-04 1978-09-15 Ile De France
US4379928A (en) * 1981-03-04 1983-04-12 Union Carbide Corporation Synthesis of amides
US5026730A (en) * 1987-08-21 1991-06-25 Ciba-Geigy Corporation Anilinophenylthioureas, compositions containing them, and the use thereof in pest control
US5111975A (en) * 1991-03-01 1992-05-12 Specialty Equipment Companies, Inc. Decanter having shock absorber

Also Published As

Publication number Publication date
ATE405543T1 (en) 2008-09-15
DE60135457D1 (en) 2008-10-02
US20030158442A1 (en) 2003-08-21
US6960689B2 (en) 2005-11-01
EP1285909B1 (en) 2008-08-20
WO2001092207A1 (en) 2001-12-06
US7087783B2 (en) 2006-08-08
JP3836425B2 (en) 2006-10-25
US20050075513A1 (en) 2005-04-07
US6803472B2 (en) 2004-10-12
US20050049421A1 (en) 2005-03-03
US20050043569A1 (en) 2005-02-24
US6946576B2 (en) 2005-09-20
EP1285909A1 (en) 2003-02-26
TWI295293B (en) 2008-04-01
EP1285909A4 (en) 2005-10-19

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