AU2001258550A1 - Insulin formulation for inhalation - Google Patents

Insulin formulation for inhalation

Info

Publication number: AU2001258550A1
Authority: AU; Australia
Prior art keywords: inhalation; insulin formulation; insulin; formulation
Prior art date: 2000-05-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2001258550A

Inventor

Jaap Kampinga

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Quadrant Drug Delivery Ltd

Original Assignee

Quadrant Healthcare UK Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-16

Filing date

2001-05-16

Publication date

2001-11-26

2001-05-16 Application filed by Quadrant Healthcare UK Ltd filed Critical Quadrant Healthcare UK Ltd

2001-11-26 Publication of AU2001258550A1 publication Critical patent/AU2001258550A1/en

Status Abandoned legal-status Critical Current

Links

NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 2
102000004877 Insulin Human genes 0.000 title 1
108090001061 Insulin Proteins 0.000 title 1
238000009472 formulation Methods 0.000 title 1
229940125396 insulin Drugs 0.000 title 1
239000000203 mixture Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Pulmonology (AREA)
Otolaryngology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

AU2001258550A 2000-05-16 2001-05-16 Insulin formulation for inhalation Abandoned AU2001258550A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB0011807		2000-05-16
GBGB0011807.5A GB0011807D0 (en)	2000-05-16	2000-05-16	Formulation for inhalation
PCT/GB2001/002181 WO2001087278A1 (en)	2000-05-16	2001-05-16	Insulin formulation for inhalation

Publications (1)

Publication Number	Publication Date
AU2001258550A1 true AU2001258550A1 (en)	2001-11-26

Family

ID=9891708

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2001258550A Abandoned AU2001258550A1 (en)	2000-05-16	2001-05-16	Insulin formulation for inhalation

Country Status (7)

Country	Link
US (1)	US20030148925A1 (en)
EP (1)	EP1282409A1 (en)
JP (1)	JP2003533472A (en)
AU (1)	AU2001258550A1 (en)
CA (1)	CA2407254A1 (en)
GB (1)	GB0011807D0 (en)
WO (1)	WO2001087278A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100291620B1 (en)	1992-09-29	2001-10-24	추후제출	Methods of delivery through the lungs of active fragments of parathyroid hormone
ATE264096T1 (en)	1994-03-07	2004-04-15	Nektar Therapeutics	METHOD AND MEANS FOR ADMINISTERING INSULIN VIA THE LUNGS
US6309623B1 (en)	1997-09-29	2001-10-30	Inhale Therapeutic Systems, Inc.	Stabilized preparations for use in metered dose inhalers
US6565885B1 (en)	1997-09-29	2003-05-20	Inhale Therapeutic Systems, Inc.	Methods of spray drying pharmaceutical compositions
US20060165606A1 (en)	1997-09-29	2006-07-27	Nektar Therapeutics	Pulmonary delivery particles comprising water insoluble or crystalline active agents
US7871598B1 (en)	2000-05-10	2011-01-18	Novartis Ag	Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US7575761B2 (en)	2000-06-30	2009-08-18	Novartis Pharma Ag	Spray drying process control of drying kinetics
GB0208742D0 (en)	2002-04-17	2002-05-29	Bradford Particle Design Ltd	Particulate materials
TW200300696A (en)	2001-11-01	2003-06-16	Inhale Therapeutic Syst	Spray drying methods and related compositions
WO2003053411A1 (en)	2001-12-19	2003-07-03	Nektar Therapeutics	Pulmonary delivery of aminoglycosides
US7582284B2 (en)	2002-04-17	2009-09-01	Nektar Therapeutics	Particulate materials
US9339459B2 (en)	2003-04-24	2016-05-17	Nektar Therapeutics	Particulate materials
GB0304540D0 (en) *	2003-02-27	2003-04-02	Elan Drug Delivery Ltd	Particle formulation and its preparation
ES2909080T3 (en)	2004-04-23	2022-05-05	Cydex Pharmaceuticals Inc	DPI formulation containing sulfoalkyl ether cyclodextrin
EP1593376A1 (en) *	2004-05-04	2005-11-09	Warner-Lambert Company LLC	Improved pullulan capsules
US7629331B2 (en)	2005-10-26	2009-12-08	Cydex Pharmaceuticals, Inc.	Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
ES2691033T3 (en)	2007-02-11	2018-11-23	Map Pharmaceuticals Inc.	Therapeutic administration method of DHE to activate rapid migraine relief while minimizing the profile of side effects
CA3215128A1 (en) *	2021-04-11	2022-10-20	Michal Olshansky	Insulin formulations and methods of using same in preterm infants

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS59163313A (en) *	1983-03-09	1984-09-14	Teijin Ltd	Peptide hormone composition for nasal administration
TW402506B (en) *	1993-06-24	2000-08-21	Astra Ab	Therapeutic preparation for inhalation
IS1796B (en) *	1993-06-24	2001-12-31	Ab Astra	Inhaled polypeptide formulation composition which also contains an enhancer compound
ATE264096T1 (en) *	1994-03-07	2004-04-15	Nektar Therapeutics	METHOD AND MEANS FOR ADMINISTERING INSULIN VIA THE LUNGS
SE9404468D0 (en) *	1994-12-22	1994-12-22	Astra Ab	Powder formulations
US6258341B1 (en) *	1995-04-14	2001-07-10	Inhale Therapeutic Systems, Inc.	Stable glassy state powder formulations
US6517860B1 (en) *	1996-12-31	2003-02-11	Quadrant Holdings Cambridge, Ltd.	Methods and compositions for improved bioavailability of bioactive agents for mucosal delivery
RU2198181C2 (en) *	1997-03-20	2003-02-10	Ново Нордиск А/С	Zinc-free insulin crystal for application in pulmonary compositions
GB9814172D0 (en) *	1998-06-30	1998-08-26	Andaris Ltd	Formulation for inhalation
US6451349B1 (en) *	1998-08-19	2002-09-17	Quadrant Healthcare (Uk) Limited	Spray-drying process for the preparation of microparticles
GB0004827D0 (en) *	2000-02-29	2000-04-19	Quadrant Holdings Cambridge	Compositions

2000
- 2000-05-16 GB GBGB0011807.5A patent/GB0011807D0/en not_active Ceased
2001
- 2001-05-16 WO PCT/GB2001/002181 patent/WO2001087278A1/en not_active Ceased
- 2001-05-16 JP JP2001583746A patent/JP2003533472A/en active Pending
- 2001-05-16 EP EP01931858A patent/EP1282409A1/en not_active Ceased
- 2001-05-16 CA CA002407254A patent/CA2407254A1/en not_active Abandoned
- 2001-05-16 US US10/258,915 patent/US20030148925A1/en not_active Abandoned
- 2001-05-16 AU AU2001258550A patent/AU2001258550A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CA2407254A1 (en)	2001-11-22
EP1282409A1 (en)	2003-02-12
JP2003533472A (en)	2003-11-11
US20030148925A1 (en)	2003-08-07
WO2001087278A1 (en)	2001-11-22
GB0011807D0 (en)	2000-07-05

Publication	Publication Date	Title
AU2002330273A1 (en)	2003-04-22	Liposome-encapsulated insulin formulations
AU2002248464A1 (en)	2002-09-12	Stabilized insulin formulations
AU2002222118A1 (en)	2002-06-11	Pharmaceutical compositions for inhalation
AU2002223028A1 (en)	2002-05-06	Inhaler
AU2002361453A1 (en)	2003-07-15	Metered dose inhaler
IL158862A0 (en)	2004-05-12	An insulin composition for pulmonary administration
WO2002089880A8 (en)	2003-04-03	Inhalers
AU2001248673A1 (en)	2001-10-30	Nasal inhaler
AU2002234476A1 (en)	2003-04-03	Medical aerosol formulations
AU2001295657A1 (en)	2002-04-22	Formulation containing wax-esters
AU2001274548A1 (en)	2002-01-02	Syringe
AU2001258550A1 (en)	2001-11-26	Insulin formulation for inhalation
AU2002253039A1 (en)	2003-02-27	Tramadol-based medicament
AU2001268750A1 (en)	2002-01-02	Flushed-seal respirator
AU2002258221A1 (en)	2003-05-08	Medicinal composition
AU2001290239A1 (en)	2002-04-02	Medicinal composition
AU2001256168A1 (en)	2001-09-12	Metered dose inhaler
AU4417101A (en)	2001-09-12	Metered dose inhaler
AU4831801A (en)	2001-09-12	Metered dose inhaler
AU2002215114A1 (en)	2002-06-11	Pharmaceutical compositions for inhalation
AU2001232244A1 (en)	2001-08-20	Drug comprising combination
AU2001260236A1 (en)	2001-11-07	Restricted use syringe
AU2001261552A1 (en)	2001-12-03	Disposable respirator
AU4417001A (en)	2001-09-12	Metered dose inhaler
AU2001267135A1 (en)	2002-01-02	Medicaments