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AU2001253867A1 - Derivatives of breast cancer antigen HER-2 for therapeutical use - Google Patents

Derivatives of breast cancer antigen HER-2 for therapeutical use

Info

Publication number
AU2001253867A1
AU2001253867A1 AU2001253867A AU5386701A AU2001253867A1 AU 2001253867 A1 AU2001253867 A1 AU 2001253867A1 AU 2001253867 A AU2001253867 A AU 2001253867A AU 5386701 A AU5386701 A AU 5386701A AU 2001253867 A1 AU2001253867 A1 AU 2001253867A1
Authority
AU
Australia
Prior art keywords
cells
cell
antigen
peptide
mhc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001253867A
Other languages
English (en)
Inventor
Charles A. Nicolette
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genzyme Corp
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of AU2001253867A1 publication Critical patent/AU2001253867A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2001253867A 2000-03-16 2001-03-16 Derivatives of breast cancer antigen HER-2 for therapeutical use Abandoned AU2001253867A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/527,487 US6528060B1 (en) 2000-03-16 2000-03-16 Therapeutic compounds
US09527487 2000-03-16
PCT/US2001/040328 WO2001068677A2 (fr) 2000-03-16 2001-03-16 Composes therapeutiques

Publications (1)

Publication Number Publication Date
AU2001253867A1 true AU2001253867A1 (en) 2001-09-24

Family

ID=24101653

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001253867A Abandoned AU2001253867A1 (en) 2000-03-16 2001-03-16 Derivatives of breast cancer antigen HER-2 for therapeutical use

Country Status (6)

Country Link
US (2) US6528060B1 (fr)
EP (2) EP1679320A1 (fr)
JP (1) JP2004505607A (fr)
AU (1) AU2001253867A1 (fr)
CA (1) CA2402721A1 (fr)
WO (1) WO2001068677A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6528060B1 (en) * 2000-03-16 2003-03-04 Genzyme Corporation Therapeutic compounds
US9068234B2 (en) 2003-01-21 2015-06-30 Ptc Therapeutics, Inc. Methods and agents for screening for compounds capable of modulating gene expression
EP1604011A4 (fr) 2003-01-21 2009-12-09 Ptc Therapeutics Inc Procedes pour identifier des composes qui modulent l'expression de genes dependants d'une region non traduite, et procedes d'utilisation correspondants
US8426194B2 (en) * 2003-01-21 2013-04-23 Ptc Therapeutics, Inc. Methods and agents for screening for compounds capable of modulating VEGF expression
US20070072186A1 (en) * 2003-11-17 2007-03-29 Anuradha Mehta Methods and agents for screening for compounds capable of modulating her2 expression
WO2005108432A2 (fr) * 2004-03-30 2005-11-17 Indiana University Research & Technology Corporation Peptides de liaison de cd80 (b7-1) et utilisations
US7737253B2 (en) * 2006-06-16 2010-06-15 Bresagen, Inc. Human cancer stem cell culture compositions comprising Erbb2 variants and methods of use thereof
US8283115B1 (en) 2007-06-20 2012-10-09 Ptc Therapeutics, Inc. Methods of screening for compounds for treating muscular dystrophy using UTRN mRNA translation regulation
US8283116B1 (en) 2007-06-22 2012-10-09 Ptc Therapeutics, Inc. Methods of screening for compounds for treating spinal muscular atrophy using SMN mRNA translation regulation
EP2545071A2 (fr) * 2010-03-09 2013-01-16 Maksyutov, Amir Constructions polyépitopiques et leurs procédés de préparation et d'utilisation

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4754065A (en) 1984-12-18 1988-06-28 Cetus Corporation Precursor to nucleic acid probe
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5837249A (en) 1985-04-19 1998-11-17 The Wistar Institute Method for generating an immunogenic T cell response protective against a virus
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
EP0573608A1 (fr) 1991-02-07 1993-12-15 Molecumetics, Ltd. Produits mimetiques de conformation restreinte de tours beta et bombements beta, et peptides les contenant
US5801005A (en) * 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
US5869445A (en) * 1993-03-17 1999-02-09 University Of Washington Methods for eliciting or enhancing reactivity to HER-2/neu protein
US5910486A (en) * 1994-09-06 1999-06-08 Uab Research Foundation Methods for modulating protein function in cells using, intracellular antibody homologues
US5643786A (en) 1995-01-27 1997-07-01 The United States Of America As Represented By The Department Of Health And Human Services Method for isolating dendritic cells
AU735459B2 (en) * 1997-01-30 2001-07-12 University Of Virginia Patent Foundation Cysteine-depleted peptides recognized by A3-restricted cytotoxic lymphocytes, and uses therefor
US6028058A (en) * 1997-07-21 2000-02-22 Ciblex Corporation Methods and compositions for regulating nuclear trafficking of proteins
US6528060B1 (en) * 2000-03-16 2003-03-04 Genzyme Corporation Therapeutic compounds

Also Published As

Publication number Publication date
CA2402721A1 (fr) 2001-09-20
US20030147905A1 (en) 2003-08-07
WO2001068677A3 (fr) 2002-05-10
US6528060B1 (en) 2003-03-04
JP2004505607A (ja) 2004-02-26
EP1287034A2 (fr) 2003-03-05
WO2001068677A2 (fr) 2001-09-20
EP1679320A1 (fr) 2006-07-12

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