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AU2001248504A1 - Immunosuppressant n-acyles homoserine lactones - Google Patents

Immunosuppressant n-acyles homoserine lactones

Info

Publication number
AU2001248504A1
AU2001248504A1 AU2001248504A AU4850401A AU2001248504A1 AU 2001248504 A1 AU2001248504 A1 AU 2001248504A1 AU 2001248504 A AU2001248504 A AU 2001248504A AU 4850401 A AU4850401 A AU 4850401A AU 2001248504 A1 AU2001248504 A1 AU 2001248504A1
Authority
AU
Australia
Prior art keywords
acyles
immunosuppressant
homoserine lactones
homoserine
lactones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001248504A
Inventor
Barrie Walsham Bycroft
Siri Ram Chhabra
Doreen Hooi
David Idris Pritchard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Nottingham
Original Assignee
University of Nottingham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Nottingham filed Critical University of Nottingham
Publication of AU2001248504A1 publication Critical patent/AU2001248504A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001248504A 2000-03-30 2001-03-29 Immunosuppressant n-acyles homoserine lactones Abandoned AU2001248504A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0007588.7A GB0007588D0 (en) 2000-03-30 2000-03-30 N-Acyl homoserine lactones
GB0007588 2000-03-30
PCT/GB2001/001435 WO2001074801A1 (en) 2000-03-30 2001-03-29 Immunosuppressant n-acyles homoserine lactones

Publications (1)

Publication Number Publication Date
AU2001248504A1 true AU2001248504A1 (en) 2001-10-15

Family

ID=9888642

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001248504A Abandoned AU2001248504A1 (en) 2000-03-30 2001-03-29 Immunosuppressant n-acyles homoserine lactones

Country Status (5)

Country Link
US (1) US20030171371A1 (en)
EP (1) EP1268459A1 (en)
AU (1) AU2001248504A1 (en)
GB (1) GB0007588D0 (en)
WO (1) WO2001074801A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6703513B1 (en) * 2000-06-02 2004-03-09 K-Quay Enterprises Llc Production and use of derivatized homoserine lactones
ATE363839T1 (en) * 2001-01-08 2007-06-15 Pathway Intermediates Ltd AUTOINDUCER COMPOUNDS AND THEIR USE
GB0116312D0 (en) 2001-07-04 2001-08-29 Univ Nottingham "Compositions containing N-acyl homoserine lactones"
GB0122026D0 (en) * 2001-09-12 2001-10-31 Univ Nottingham Insulitis
ES2382075T3 (en) 2002-08-13 2012-06-05 Haptogen Ltd Procedures for the treatment of an infectious bacterial disease with an antibody against signal molecules derived from an antilactone or a lactone
US7537906B2 (en) * 2003-01-29 2009-05-26 Nobuhiko Nomura Apoptosis inducer and method of screening for a substance inhibiting acylated homoserine lactone
GB0407008D0 (en) 2004-03-27 2004-04-28 Haptogen Ltd Methods for inducing rapid cell death (autolysis) in infectious bacteria
GB0410958D0 (en) 2004-05-15 2004-06-16 Haptogen Ltd Methods for reducing biofilm formation in infectious bacteria
GB0610042D0 (en) * 2006-05-22 2006-06-28 Univ Nottingham Substituted n-acyl homoserine lactones
KR100841294B1 (en) 2006-12-04 2008-06-25 재단법인서울대학교산학협력재단 Homoserine lactone-based quorum recognition antagonist and method for preventing biofilm formation using the same
CN102482244B (en) * 2009-07-03 2015-09-09 内盖夫国家生物技术有限公司 Covalent inhibition of bacterial quorum sensing
WO2014201507A1 (en) * 2013-06-21 2014-12-24 Technological Resources Pty. Limited Homoserine lactone derivatives for improving elemental recovery during biomining
TWI594991B (en) * 2015-06-30 2017-08-11 中央研究院 Novel glucagon-like peptide 1 modulator and uses thereof
WO2017058757A1 (en) * 2015-10-01 2017-04-06 The University Of Toledo Use of acyl-homoserine lactone derivatives as anti-thrombotic agents
FR3102357B1 (en) * 2019-10-23 2022-06-24 Univ Sorbonne N-ACYL-HOMOSERINE LACTONE ANALOGS AND PHARMACEUTICAL COMPOSITION COMPRISING THEM

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415493A (en) * 1982-05-11 1983-11-15 Scripps Clinic And Research Foundation Immune modulator peptides
GB9108307D0 (en) * 1991-04-18 1991-06-05 Univ Nottingham Autoinducer
WO1995001175A1 (en) * 1993-07-02 1995-01-12 The University Of Nottingham Immunosuppressant and antiallergic compounds, e.g. n-(3-oxohexanoyl) homoserine lactone
US5591872A (en) * 1993-08-09 1997-01-07 The University Of Iowa Research Foundation Autoinducer molecule
EP0994961B1 (en) * 1997-06-18 2006-10-18 Montana State University - Bozeman Homoserine lactones biofilm regulating compounds and their methods of use
GB9725599D0 (en) * 1997-12-04 1998-02-04 Univ Nottingham Control of biofilm formation
US6395282B1 (en) * 1998-04-16 2002-05-28 University Of Rochester Immunogenic conjugates of Gram-negative bacterial autoinducer molecules
US6337347B1 (en) * 1998-06-18 2002-01-08 The Research & Development Institute, Inc. Autoinducer compounds

Also Published As

Publication number Publication date
GB0007588D0 (en) 2000-05-17
EP1268459A1 (en) 2003-01-02
US20030171371A1 (en) 2003-09-11
WO2001074801A1 (en) 2001-10-11

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