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AU2001245382A1 - Simultaneous multimodal measurement of physiological function - Google Patents

Simultaneous multimodal measurement of physiological function

Info

Publication number
AU2001245382A1
AU2001245382A1 AU2001245382A AU4538201A AU2001245382A1 AU 2001245382 A1 AU2001245382 A1 AU 2001245382A1 AU 2001245382 A AU2001245382 A AU 2001245382A AU 4538201 A AU4538201 A AU 4538201A AU 2001245382 A1 AU2001245382 A1 AU 2001245382A1
Authority
AU
Australia
Prior art keywords
physiological function
simultaneous multimodal
multimodal measurement
measurement
simultaneous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001245382A
Inventor
Samuel I. Achilefu
Joseph E. Bugaj
Arthur H. Combs
Richard B. Dorshow
Raghavan Rajagopalan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Publication of AU2001245382A1 publication Critical patent/AU2001245382A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow
    • A61B5/0275—Measuring blood flow using tracers, e.g. dye dilution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/412—Detecting or monitoring sepsis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A61K49/0034—Indocyanine green, i.e. ICG, cardiogreen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
    • A61K49/0043—Fluorescein, used in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056—Peptides, proteins, polyamino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A61B5/0086—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters using infrared radiation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2001245382A 2000-03-06 2001-03-01 Simultaneous multimodal measurement of physiological function Abandoned AU2001245382A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/519,455 US6280703B1 (en) 1997-03-13 2000-03-06 Simultaneous multimodal measurement of physiological function
US09519455 2000-03-06
PCT/US2001/006589 WO2001066152A1 (en) 2000-03-06 2001-03-01 Simultaneous multimodal measurement of physiological function

Publications (1)

Publication Number Publication Date
AU2001245382A1 true AU2001245382A1 (en) 2001-09-17

Family

ID=24068379

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001245382A Abandoned AU2001245382A1 (en) 2000-03-06 2001-03-01 Simultaneous multimodal measurement of physiological function

Country Status (5)

Country Link
US (1) US6280703B1 (en)
EP (2) EP1604689A1 (en)
JP (1) JP2003525914A (en)
AU (1) AU2001245382A1 (en)
WO (1) WO2001066152A1 (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0934986A1 (en) * 1997-12-17 1999-08-11 Roche Diagnostics GmbH Dye-polysaccharide or -cyclosaccharide conjugates and their use as diagnostic agent
US7474906B2 (en) * 2001-05-22 2009-01-06 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Method for dye injection for the transcutaneous measurement of cardiac output
US8337444B2 (en) * 2001-05-22 2012-12-25 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Measurement of cardiac output and blood volume by non-invasive detection of indicator dilution for hemodialysis
US6757554B2 (en) * 2001-05-22 2004-06-29 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Measurement of cardiac output and blood volume by non-invasive detection of indicator dilution
US20080027298A1 (en) * 2001-05-22 2008-01-31 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern Californ System for Repetitive Measurements of Cardiac Output in Freely Moving Individuals
DE10225932B4 (en) * 2002-06-11 2007-01-11 Deutsches Krebsforschungszentrum (Dkfz) Imaging method and apparatus for carrying it out
US7149562B2 (en) * 2002-09-17 2006-12-12 The United States Of America As Represented By The Secretary Of The Army Needle with fiberoptic capability
AU2003299565A1 (en) * 2002-11-27 2004-06-23 Board Of Regents, The University Of Texas System Radiopharmaceuticals and radioactive microspheres for locoregional ablation of abnormal tissues
US7226577B2 (en) 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
US7322971B2 (en) * 2003-02-07 2008-01-29 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Surgical drain with sensors for monitoring internal tissue condition by transmittance
DE502004003658D1 (en) * 2003-05-30 2007-06-14 Siemens Ag Device for detecting at least one substance in a metabolic process of a living being
CA2649391C (en) 2005-04-19 2017-11-28 Indiana University Research And Technology Corporation Method and apparatus for kidney function analysis
EP1981401A4 (en) 2006-01-20 2010-07-21 Alfred E Mann Inst Biomed Eng MEASURING CARDIAC FLOW AND BLOOD VOLUME BY NON-INVASIVE DETERMINATION OF INDICATOR DILUTION
WO2007106142A2 (en) * 2006-02-24 2007-09-20 Mallinckrodt Inc. Process for using optical agents
US8725225B2 (en) * 2006-08-10 2014-05-13 University Of Rochester Intraoperative imaging of renal cortical tumors and cysts
DE102007007738A1 (en) * 2007-02-09 2008-08-14 Südzucker AG Mannheim/Ochsenfurt Color-labeled oligo- or polysaccharides
WO2009061769A1 (en) * 2007-11-06 2009-05-14 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern Califorina Measurement of hematocrit and cardiac output from optical transmission and reflection changes
JP2011521899A (en) * 2008-04-18 2011-07-28 ファーマコフォトニクス，インコーポレイティド Method and apparatus for analyzing renal function
US8591865B2 (en) * 2008-04-18 2013-11-26 Pharmacophotonics, Inc. Renal function analysis method and apparatus
JP5644498B2 (en) * 2008-07-17 2014-12-24 コニカミノルタ株式会社 Nanoparticle labeling agent and system using the nanoparticle labeling agent
US9433700B2 (en) 2009-04-27 2016-09-06 Medibeacon Inc. Tissue sealant compositions, vascular closure devices, and uses thereof
EP2459053A2 (en) * 2009-07-28 2012-06-06 F. Hoffmann-La Roche AG Non-invasive in vivo optical imaging method
US8313477B2 (en) 2010-03-05 2012-11-20 See Jackie R Device and methods for monitoring the administration of a stem cell transplant
EP2598174B1 (en) * 2010-07-30 2019-03-27 SmartDyeLivery GmbH Measurement method for determining an organ function
US10823673B2 (en) 2016-11-23 2020-11-03 Ysi, Inc. Dual function fluorometer-absorbance sensor
US11013436B2 (en) 2017-09-06 2021-05-25 Medtronic, Inc. Marker monitoring via a medical device
RU2760279C2 (en) 2017-10-27 2021-11-23 Медибикон Инк. Compositions and systems for evaluating kidney function

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL84356A (en) 1986-11-05 1991-08-16 Sumitomo Electric Industries Liver function testing apparatus
US4848349A (en) 1987-04-29 1989-07-18 Sherman Igor A Substance and method for measuring hepatic blood flow
KR910002651B1 (en) 1987-11-13 1991-04-27 스미또모 덴끼 고교 가부시끼가이샤 Liver function search instrument
JPH01129838A (en) 1987-11-13 1989-05-23 Sumitomo Electric Ind Ltd Liver function examination apparatus
JPH02309929A (en) 1989-05-24 1990-12-25 Sumitomo Electric Ind Ltd Liver function testing device
US5699798A (en) * 1990-08-10 1997-12-23 University Of Washington Method for optically imaging solid tumor tissue
US5845639A (en) * 1990-08-10 1998-12-08 Board Of Regents Of The University Of Washington Optical imaging methods
US5301673A (en) 1991-11-18 1994-04-12 Massachusetts General Hospital Ambulatory clearance function monitor
US5458128A (en) 1994-06-17 1995-10-17 Polanyi; Michael Method and apparatus for noninvasively measuring concentration of a dye in arterial blood
DE4445065A1 (en) 1994-12-07 1996-06-13 Diagnostikforschung Inst Methods for in-vivo diagnostics using NIR radiation
GB9517043D0 (en) 1995-08-19 1995-10-25 Univ Birmingham The use of bile acid derivatives
US5900228A (en) * 1996-07-31 1999-05-04 California Institute Of Technology Bifunctional detection agents having a polymer covalently linked to an MRI agent and an optical dye
JP2002512594A (en) * 1996-12-11 2002-04-23 ファーマサイクリックス，インコーポレイテッド Use of texaphyrin in ophthalmic diagnosis and treatment
US5928625A (en) 1997-03-13 1999-07-27 Mallinckrodt Inc. Method of measuring physiological function

Also Published As

Publication number Publication date
EP1263477A1 (en) 2002-12-11
WO2001066152A1 (en) 2001-09-13
US6280703B1 (en) 2001-08-28
EP1263477A4 (en) 2003-06-18
EP1604689A1 (en) 2005-12-14
JP2003525914A (en) 2003-09-02

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