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AU2001244275A1 - Pneumococcus polysaccharide conjugates for use as vaccine against tetanus and diphtheria - Google Patents

Pneumococcus polysaccharide conjugates for use as vaccine against tetanus and diphtheria

Info

Publication number
AU2001244275A1
AU2001244275A1 AU2001244275A AU4427501A AU2001244275A1 AU 2001244275 A1 AU2001244275 A1 AU 2001244275A1 AU 2001244275 A AU2001244275 A AU 2001244275A AU 4427501 A AU4427501 A AU 4427501A AU 2001244275 A1 AU2001244275 A1 AU 2001244275A1
Authority
AU
Australia
Prior art keywords
diphtheria
vaccine against
polysaccharide conjugates
against tetanus
conjugated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001244275A
Inventor
Dominique Schulz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur SA
Original Assignee
Aventis Pasteur SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8848189&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2001244275(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pasteur SA filed Critical Aventis Pasteur SA
Publication of AU2001244275A1 publication Critical patent/AU2001244275A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/08—Clostridium, e.g. Clostridium tetani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The invention relates to the use of a composition comprising n Streptococcus pneumoniae polysaccharides conjugated to the tetanus toxoid and p Streptococcus pneumoniae polysaccharides conjugated to the diphtheria toxoid, for manufacturing a vaccine which protects against Clostridium tetani and/or Corynebacterium diphtheriae infections in which: (1) n and p are other than 1, with p being, however, <=15, (2) 2<=n+p<=38, (3) the total amount of conjugated toxoid present in one vaccine dose is sufficient to induce protection against Clostridium tetani and/or Corynebacterium diphtheriae infections.
AU2001244275A 2000-03-17 2001-03-19 Pneumococcus polysaccharide conjugates for use as vaccine against tetanus and diphtheria Abandoned AU2001244275A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0003407 2000-03-17
FR0003407A FR2806304B1 (en) 2000-03-17 2000-03-17 POLYSACCHARIDIC CONJUGATES OF PNEUMOCOCCUS FOR VACCINE USE AGAINST TETANUS AND DIPHTHERIA
PCT/FR2001/000820 WO2001068128A1 (en) 2000-03-17 2001-03-19 Pneumococcus polysaccharide conjugates for use as vaccine against tetanus and diphtheria

Publications (1)

Publication Number Publication Date
AU2001244275A1 true AU2001244275A1 (en) 2001-09-24

Family

ID=8848189

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001244275A Abandoned AU2001244275A1 (en) 2000-03-17 2001-03-19 Pneumococcus polysaccharide conjugates for use as vaccine against tetanus and diphtheria

Country Status (11)

Country Link
US (1) US20030099672A1 (en)
EP (1) EP1267922B1 (en)
AT (1) ATE297758T1 (en)
AU (1) AU2001244275A1 (en)
CA (1) CA2402807A1 (en)
DE (1) DE60111507T2 (en)
DK (1) DK1267922T3 (en)
ES (1) ES2240432T3 (en)
FR (1) FR2806304B1 (en)
PT (1) PT1267922E (en)
WO (1) WO2001068128A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002000249A2 (en) * 2000-06-29 2002-01-03 Glaxosmithkline Biologicals S.A. Multivalent vaccine composition
DK2283857T3 (en) 2005-06-27 2019-10-28 Glaxosmithkline Biologicals Sa Vaccine composition comprising conjugated native N. Meningitidis capsule polysaccharides
GB0607088D0 (en) * 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
ES2707499T3 (en) 2005-12-22 2019-04-03 Glaxosmithkline Biologicals Sa Pneumococcal polysaccharide conjugate vaccine
EA201391788A1 (en) 2007-06-26 2014-08-29 Глаксосмитклайн Байолоджикалс С.А. VACCINE CONTAINING CONJUGATES OF CAPSULAR POLYSACCHARIDES STREPTOCOCCUS PNEUMONIAE
GB2495341B (en) * 2011-11-11 2013-09-18 Novartis Ag Fermentation methods and their products
KR102057217B1 (en) * 2012-06-20 2020-01-22 에스케이바이오사이언스 주식회사 Multivalent pneumococcal polysaccharide-protein conjugate composition
ITMI20121597A1 (en) * 2012-09-25 2014-03-26 Beta Pharma S A CONJUGATE BETWEEN FRAGRANCE OF BACTERIAL CELL WALL AND A MUCOPOLYSACCHARID VEHICLE AND ITS USES IN MEDICAL AREA
KR20140075196A (en) 2012-12-11 2014-06-19 에스케이케미칼주식회사 Multivalent pneumococcal polysaccharide-protein conjugate composition
CA2894260A1 (en) * 2012-12-18 2014-06-26 Glaxosmithkline Biologicals S.A. Conjugates for protecting against diphtheria and/or tetanus
US9107906B1 (en) 2014-10-28 2015-08-18 Adma Biologics, Inc. Compositions and methods for the treatment of immunodeficiency
TWI789357B (en) * 2016-08-05 2023-01-11 南韓商Ｓｋ生物科技股份有限公司 Multivalent pneumococcal polysaccharide-protein conjugate composition
CA3031797A1 (en) 2016-08-05 2018-02-08 Sanofi Pasteur, Inc. Multivalent pneumococcal polysaccharide-protein conjugate composition
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
MX2019014829A (en) 2017-06-10 2020-08-17 Inventprise Llc MULTIVALENT CONJUGATE VACCINES WITH BIVALENT OR MULTIVALENT CONJUGATE POLYSACCHARIDES THAT PROVIDE ENHANCED IMMUNOGENICITY AND AVIDITY.
EP3749358A4 (en) 2018-02-05 2022-04-20 Sanofi Pasteur, Inc. MULTIVALENT POLYSACCHARIDE-PNEUMOCOCCAL PROTEIN CONJUGATE COMPOSITION
KR102486891B1 (en) 2018-02-05 2023-01-10 사노피 파스퇴르 인코포레이티드 Polyvalent pneumococcal polysaccharide-protein conjugate composition
US11951162B2 (en) 2018-04-18 2024-04-09 Sk Bioscience Co., Ltd. Streptococcus pneumoniae capsular polysaccharides and immunogenic conjugate thereof
KR20220042378A (en) * 2019-07-31 2022-04-05 사노피 파스퇴르 인코포레이티드 Polyvalent pneumococcal polysaccharide-protein conjugate composition and method of use thereof
WO2022035816A1 (en) 2020-08-10 2022-02-17 Inventprise, Llc Multivalent pneumococcal glycoconjugate vaccines containing emerging serotype 24f
CN113607939B (en) * 2021-08-05 2024-10-22 艾美探索者生命科学研发有限公司 Method for determining the adsorption rate of various types of pneumococcal polysaccharide conjugate vaccines

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4619828A (en) * 1982-07-06 1986-10-28 Connaught Laboratories, Inc. Polysaccharide exotoxoid conjugate vaccines
US5204098A (en) * 1988-02-16 1993-04-20 The United States Of America As Represented By The Department Of Health And Human Services Polysaccharide-protein conjugates
US5153312A (en) * 1990-09-28 1992-10-06 American Cyanamid Company Oligosaccharide conjugate vaccines
FR2682388B1 (en) * 1991-10-10 1995-06-09 Pasteur Merieux Serums Vacc PROCESS FOR THE PREPARATION OF AN OLIGOSIDE BY DEPOLYMERIZATION OF A POLYOSIDE DERIVED FROM A PATHOGENIC AGENT, OLIGOSIDE THUS OBTAINED AND ITS USE IN PARTICULAR AS A VACCINE AGENT.
JP4233113B2 (en) * 1995-06-07 2009-03-04 グラクソスミスクライン・バイオロジカルス・ソシエテ・アノニム Vaccine comprising polysaccharide antigen-carrier protein conjugate and free carrier protein
FR2763244B1 (en) * 1997-05-14 2003-08-01 Pasteur Merieux Serums Vacc MULTIVALENT VACCINE COMPOSITION WITH MIXED CARRIER
AU763349B2 (en) * 1998-02-05 2003-07-17 Henry M. Jackson Foundation For The Advancement Of Military Medicine Simplified method for removing free protein during preparation of protein-polysaccharide conjugates and vaccines using restricted-access media

Also Published As

Publication number Publication date
ES2240432T3 (en) 2005-10-16
CA2402807A1 (en) 2001-09-20
WO2001068128A1 (en) 2001-09-20
EP1267922B1 (en) 2005-06-15
ATE297758T1 (en) 2005-07-15
DE60111507T2 (en) 2006-05-11
PT1267922E (en) 2005-09-30
FR2806304A1 (en) 2001-09-21
EP1267922A1 (en) 2003-01-02
FR2806304B1 (en) 2002-05-10
DK1267922T3 (en) 2005-10-17
DE60111507D1 (en) 2005-07-21
US20030099672A1 (en) 2003-05-29

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