AU2001244088A1 - Condensed imidazoles as histamine h3 receptor ligands - Google Patents

Condensed imidazoles as histamine h3 receptor ligands

Info

Publication number: AU2001244088A1
Authority: AU; Australia
Prior art keywords: histamine; receptor ligands; condensed imidazoles; imidazoles; condensed
Prior art date: 2000-03-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2001244088A

Inventor

Knud Erik Andersen

Florencio Zaragoza Dorwald

Birgitte Eriksen

Rudolf Hurnaus

Bernd Krist

Stephan Georg Muller

Bernd Pesche

Klaus Rudolf

Ulla Grove Sidelmann

Dirk Stenkamp

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Boehringer Ingelheim International GmbH

Novo Nordisk AS

Original Assignee

Boehringer Ingelheim International GmbH

Novo Nordisk AS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-03-17

Filing date

2001-03-16

Publication date

2001-09-24

2001-03-16 Application filed by Boehringer Ingelheim International GmbH, Novo Nordisk AS filed Critical Boehringer Ingelheim International GmbH

2001-09-24 Publication of AU2001244088A1 publication Critical patent/AU2001244088A1/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Hematology (AREA)
Obesity (AREA)
Immunology (AREA)
Emergency Medicine (AREA)
Child & Adolescent Psychology (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Anesthesiology (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AU2001244088A 2000-03-17 2001-03-16 Condensed imidazoles as histamine h3 receptor ligands Abandoned AU2001244088A1 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
DKPA200000441		2000-03-17
DKPA200000441		2000-03-17
DKPA200001016		2000-06-29
DKPA200001016		2000-06-29
PCT/DK2001/000188 WO2001068652A1 (en)	2000-03-17	2001-03-16	Condensed imidazoles as histamine h3 receptor ligands

Publications (1)

Publication Number	Publication Date
AU2001244088A1 true AU2001244088A1 (en)	2001-09-24

Family

ID=26068796

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2001244088A Abandoned AU2001244088A1 (en)	2000-03-17	2001-03-16	Condensed imidazoles as histamine h3 receptor ligands

Country Status (4)

Country	Link
EP (1)	EP1268484A1 (en)
JP (1)	JP2003527395A (en)
AU (1)	AU2001244088A1 (en)
WO (1)	WO2001068652A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2461603A1 (en) *	2001-09-24	2003-04-03	Elan Pharmaceuticals, Inc.	Substituted amines for the treatment of neurological disorders
MXPA04005427A (en)	2001-12-10	2005-04-19	Amgen Inc	Vanilloid receptor ligands and their use in treatments.
EP1780196A3 (en) *	2001-12-10	2007-05-09	Amgen, Inc	Pyridine derivatives for use as vanilloid receptor ligands
JP2003192587A (en) *	2001-12-26	2003-07-09	Bayer Ag	Urea derivative
US7105513B2 (en)	2002-08-07	2006-09-12	Sanofi-Avertis Deutschland Gmbh	Acylated, heteroaryl-condensed cycloalkenylamines and their use as pharmaceuticals
EP1388342A1 (en) *	2002-08-07	2004-02-11	Aventis Pharma Deutschland GmbH	Acylated, heteroaryl-condensed cycloalkenylamines and their use as pharmaceuticals
EP1585731A2 (en) *	2002-09-18	2005-10-19	Eli Lilly And Company	Histamine h3 receptor antagonists, preparaton and therapeutic uses
EP1638950A4 (en) *	2003-06-17	2010-06-30	Merck Sharp & Dohme	CYCLOHEXYLGLYCIN DERIVATIVES AS INHIBITORS OF DIPEPTIDYL PEPTIDASE FOR THE TREATMENT OR PREVENTION OF DIABETES
WO2005009471A1 (en) *	2003-07-28	2005-02-03	Osaka Industrial Promotion Organization	Composition for lowering blood-sugar level
AU2011295725B2 (en)	2010-09-03	2015-03-26	Forma Tm, Llc.	Novel compounds and compositions for the inhibition of NAMPT
CN102452988B (en) *	2010-10-27	2016-01-27	中国科学院化学研究所	A kind of quinazoline derivant and preparation method thereof
US9266840B2 (en)	2011-10-18	2016-02-23	Astellas Pharma Inc.	Bicyclic heterocyclic compound
WO2013151982A1 (en)	2012-04-03	2013-10-10	Arena Pharmaceuticals, Inc.	Methods and compounds useful in treating pruritus, and methods for identifying such compounds
US20140057920A1 (en)	2012-08-23	2014-02-27	Boehringer Ingelheim International Gmbh	Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity
CN108314641B (en) *	2017-12-27	2020-11-13	阜新龙瑞药业有限责任公司	Preparation method of natural product Norpsilocin
JP7184383B2 (en)	2018-02-01	2022-12-06	ザ・ユニバーシティ・オブ・シドニー	anticancer compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2004911A1 (en) *	1988-12-22	1990-06-22	Mitsuaki Ohta	4,5,6,7-tetrahydrobenzimidazole derivatives
ES2095855T3 (en) *	1989-02-02	1997-03-01	Yamanouchi Pharma Co Ltd	DERIVATIVES OF TETRAHIDROBENCIMIDAZOL.
JPH049372A (en) *	1990-04-25	1992-01-14	Yamanouchi Pharmaceut Co Ltd	4,5,6,7-tetrahydrobenzimidazole derivative
WO1995009167A1 (en) *	1993-09-30	1995-04-06	Tokyo Tanabe Company Limited	Indoline derivative and 5-ht3 receptor antagonist containing the same as active ingredient

2001
- 2001-03-16 WO PCT/DK2001/000188 patent/WO2001068652A1/en not_active Ceased
- 2001-03-16 EP EP01916934A patent/EP1268484A1/en not_active Withdrawn
- 2001-03-16 AU AU2001244088A patent/AU2001244088A1/en not_active Abandoned
- 2001-03-16 JP JP2001567743A patent/JP2003527395A/en active Pending

Also Published As

Publication number	Publication date
WO2001068652A1 (en)	2001-09-20
EP1268484A1 (en)	2003-01-02
JP2003527395A (en)	2003-09-16

Publication	Publication Date	Title
AU2002244271A1 (en)	2002-09-24	Non-imidazole compounds as histamine h3 antagonists
AU2002254114A1 (en)	2002-10-08	Non-imidazole aryl alkylamines compounds as histamine h3 receptor antagonists, preparation and therapeutic uses
MXPA03006773A (en)	2003-10-24	Imidazole derivatives.
MXPA03000939A (en)	2003-06-24	Imidazole derivatives.
AU2001234128A1 (en)	2001-11-15	Novel imidazoline compounds
IL165611A0 (en)	2006-01-15	1H-1,2,4-triazole-3-carboxamide derivatives as cannabinoid-cb1 receptor ligands
GB0225807D0 (en)	2002-12-11	Composite packer cup
AU2001244088A1 (en)	2001-09-24	Condensed imidazoles as histamine h3 receptor ligands
AU2002259043A1 (en)	2002-11-11	Improved composite tubing
AU2002348503A1 (en)	2002-12-23	Quinuclidine-substituted heteroaromatic compounds as ligands at nicotinic acetylcholine receptors
AU2001264657A1 (en)	2001-11-26	Crf receptor antagonists
ZA200102833B (en)	2001-10-08	Organosilicon compounds.
MXPA03008205A (en)	2004-01-29	Process for the preparation of imidazole compounds.
AU1073501A (en)	2001-05-10	Histamine receptor
MXPA03002446A (en)	2003-06-19	Substituted imidazoles as dual histamine h1.
AU2001263288A1 (en)	2001-11-26	Crf receptor antagonists
AU2001244087A1 (en)	2001-09-24	Condensed imidazoles as histamine h3 receptor ligands
SI1261588T1 (en)	2005-02-28	IMIDAZOLE COMPOUNDS AS Alpha2-ADRENOCEPTORS ANTAGONISTS
MXPA03006408A (en)	2003-10-15	Histamine receptor antagonists.
MXPA03002445A (en)	2003-06-19	Substituted imidazoles as dual histamine h1.
AU3324700A (en)	2000-10-09	Imidazole compounds
AUPQ515700A0 (en)	2000-02-10	Imidazole compounds
AU2002354016A1 (en)	2003-05-26	Histamine receptor h3 polynucleotides
AU2002306841A1 (en)	2002-10-15	Imidazolyl derivatives useful as histamine h3 receptor ligands
MXPA03009930A (en)	2004-01-29	Crf receptor antagonists.