AU1200799A - Isopropyl ester prodrugs of indole spla2 inhibitors - Google Patents
Isopropyl ester prodrugs of indole spla2 inhibitorsInfo
- Publication number
- AU1200799A AU1200799A AU12007/99A AU1200799A AU1200799A AU 1200799 A AU1200799 A AU 1200799A AU 12007/99 A AU12007/99 A AU 12007/99A AU 1200799 A AU1200799 A AU 1200799A AU 1200799 A AU1200799 A AU 1200799A
- Authority
- AU
- Australia
- Prior art keywords
- isopropyl ester
- ester prodrugs
- spla2 inhibitors
- indole spla2
- indole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 2
- -1 Isopropyl ester Chemical class 0.000 title 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 title 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 229940002612 prodrug Drugs 0.000 title 1
- 239000000651 prodrug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6328497P | 1997-10-27 | 1997-10-27 | |
| US60063284 | 1997-10-27 | ||
| PCT/US1998/022678 WO1999021545A1 (en) | 1997-10-27 | 1998-10-26 | ISOPROPYL ESTER PRODRUGS OF INDOLE sPLA2 INHIBITORS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU1200799A true AU1200799A (en) | 1999-05-17 |
Family
ID=22048190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU12007/99A Abandoned AU1200799A (en) | 1997-10-27 | 1998-10-26 | Isopropyl ester prodrugs of indole spla2 inhibitors |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU1200799A (en) |
| WO (1) | WO1999021545A1 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2301586A1 (en) * | 1997-08-28 | 1999-03-04 | William Louis Macias | Method for treatment of non-rheumatoid arthritis |
| CA2308443A1 (en) * | 1997-10-27 | 1999-05-06 | Michael Lyle Denney | Morpholino-n-ethyl ester prodrugs of indole spla2 inhibitors |
| EP1030661A4 (en) * | 1997-10-27 | 2002-07-17 | Lilly Co Eli | N,N-DIETHYLGLYCOLAMIDO ESTER PRODRUGS OF INDOLE sPLA 2? INHIBITORS |
| DE19962300A1 (en) * | 1999-12-23 | 2001-06-28 | Asta Medica Ag | New N-benzylindolyl glyoxylic acid derivatives are useful as antitumor agents |
| WO2002005796A2 (en) * | 2000-07-14 | 2002-01-24 | Eli Lilly And Company | Use of a spla2 inhibitor for the treatment of sepsis |
| AUPS282602A0 (en) | 2002-06-07 | 2002-06-27 | Garvan Institute Of Medical Research | Method of inhibiting cell proliferation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2146097C (en) * | 1994-04-01 | 2000-03-21 | Nicholas James Bach | 1h-indole-3-glyoxylamide spla2 inhibitors |
-
1998
- 1998-10-26 AU AU12007/99A patent/AU1200799A/en not_active Abandoned
- 1998-10-26 WO PCT/US1998/022678 patent/WO1999021545A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999021545A1 (en) | 1999-05-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |